Specific decrease in the level of Hic-5, a focal adhesion protein, during immortalization of mouse embryonic fibroblasts, and its association with focal adhesion kinase

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1995 • 1,810 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Inhibition of Cell Migration, Spreading, and Focal Adhesions by Tumor Suppressor PTEN

1998 • 1,215 citations

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

1997 • 802 citations

Paxillin: a new vinculin-binding protein present in focal adhesions.

1990 • 687 citations

p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts.

1991 • 455 citations

The LIM domain is a modular protein-binding interface

1994 • 450 citations

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

1995 • 385 citations

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding.

1996 • 347 citations

Integrins, Oncogenes, and Anchorage Independence

1997 • 345 citations

Assembly of focal adhesions: progress, paradigms, and portents

1996 • 265 citations

Characterization of the TGF beta 1-inducible hic-5 gene that encodes a putative novel zinc finger protein and its possible involvement in cellular senescence.

1994 • 207 citations

Cell Adhesion Kinase β Forms a Complex with a New Member, Hic-5, of Proteins Localized at Focal Adhesions

1998 • 127 citations

Fibronectin expression increases during in vitro cellular senescence: Correlation with increased cell area

1991 • 113 citations

Combination of Gene Targeting and Substrate Trapping to Identify Substrates of Protein Tyrosine Phosphatases Using PTP-PEST as a Model

1998 • 105 citations

Differential Subcellular Distribution of Mortalin in Mortal and Immortal Mouse and Human Fibroblasts

1993 • 105 citations

Cell-adhesion-dependent influences on genomic instability and carcinogenesis

1998 • 101 citations

Induction of Senescence-Like Phenotypes by Forced Expression of hic-5, Which Encodes a Novel LIM Motif Protein, in Immortalized Human Fibroblasts

1997 • 97 citations

Leupaxin Is a Novel LIM Domain Protein That Forms a Complex with PYK2

1998 • 92 citations

Hic-5, a Paxillin Homologue, Binds to the Protein-tyrosine Phosphatase PEST (PTP-PEST) through Its LIM 3 Domain

1999 • 89 citations

Interaction of Hic-5, A Senescence-related Protein, with Focal Adhesion Kinase

1998 • 84 citations

Regulation of collagenase and collagenase mRNA production in early‐ and late‐passage human diploid fibroblasts

1989 • 66 citations

Partial reversion of the transformed phenotype in HRAS-transfected tumorigenic cells by transfer of a human gene.

1988 • 61 citations

Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts

1998 • 60 citations

Recruitment of the LIM protein hic-5 to focal contacts of human platelets

1998 • 54 citations

Why Are Human Cells Resistant to Malignant Cell Transformation in vitro?¹

1993 • 52 citations

SV40 T-antigen is required for maintenance of immortal growth in SV40-transformed human fibroblasts.

1991 • 29 citations

Immortalization-susceptible elements and their binding factors mediate rejuvenation of regulation of the type I collagenase gene in simian virus 40 large T antigen-transformed immortal human fibroblasts.

1994 • 21 citations

Cloning of cDNAs with possible association with senescence and immortalization of human cells

1994 • 18 citations

Alterations of Expression of the Cytoskeleton after Immortalization of Human Fibroblasts.

1995 • 18 citations

Forced expression of hic-5, a senescence-related gene, potentiates a differentiation process of RCT-1 cells induced by retinoic acid

1998 • 18 citations

Differential gene expression in SV40-mediated immortalization of human fibroblasts

1997 • 11 citations