A phase II study of paclitaxel in heavily pretreated patients with small-cell lung cancer

Promotion of microtubule assembly in vitro by taxol

1979 • 3,521 citations

Paclitaxel (Taxol)

1995 • 1,747 citations

p53 Status and the Efficacy of Cancer Therapy in Vivo

1994 • 1,483 citations

Clinical toxicities encountered with paclitaxel (Taxol).

1993 • 682 citations

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

1996 • 654 citations

Chemotherapy of Lung Cancer

1992 • 434 citations

Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents.

1996 • 298 citations

Paclitaxel for platinum-refractory ovarian cancer: results from the first 1,000 patients registered to National Cancer Institute Treatment Referral Center 9103.

1993 • 275 citations

MDR1 Gene Expression in Lung Cancer

1989 • 182 citations

Phase II study of paclitaxel in patients with extensive-disease small-cell lung cancer: an Eastern Cooperative Oncology Group study.

1995 • 178 citations

Retreatment with the induction regimen in small cell lung cancer relapsing after an initial response to short term chemotherapy

1987 • 155 citations

Synergistic interaction between cisplatin and taxol in human ovarian carcinoma cells in vitro

1994 • 129 citations

Paclitaxel activity in heavily pretreated breast cancer: a National Cancer Institute Treatment Referral Center trial.

1995 • 125 citations

Resistance mechanisms in human sarcoma mutants derived by single-step exposure to paclitaxel (Taxol).

1996 • 113 citations

p53 mutations do not predict response to paclitaxel/radiation for nonsmall cell lung carcinoma

1996 • 70 citations

Single-agent chemotherapy trials in small-cell lung cancer, 1970 to 1990: the case for studies in previously treated patients.

1992 • 67 citations

Testing the possible non-cross resistance of two equipotent combination chemotherapy regimens against small-cell lung cancer: A phase II study of the EORTC lung cancer cooperative group

1993 • 29 citations

Paclitaxel, carboplatin, and extended schedule etoposide in the treatment of small cell lung carcinoma

1996 • 27 citations

Second-line chemotherapy in small cell lung cancer

1990 • 21 citations

A phase II study of carboplatin and vincristine in previously treated patients with small-cell lung cancer

1989 • 15 citations