Functional Implications of a Newly Characterized Pathway of 11,12-Epoxyeicosatrienoic Acid Metabolism in Arterial Smooth Muscle

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

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Endothelium-Dependent Hyperpolarization

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Renal cytochrome P450-related arachidonate metabolite inhibits (Na+ + K+)ATPase

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Role of Cytochrome P-450 Enzymes and Metabolites of Arachidonic Acid in the Control of Vascular Tone

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Cytochrome P450 and the arachidonate cascade ¹

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Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle

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1992 • 210 citations

Activation of K+ channel in vascular smooth muscles by cytochrome P450 metabolites of arachidonic acid

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Display of the characteristics of endothelium‐derived hyperpolarizing factor by a cytochrome P450‐derived arachidonic acid metabolite in the coronary microcirculation

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Dilation of cerebral arterioles by cytochrome P-450 metabolites of arachidonic acid

1990 • 147 citations

Oxygenation of polyunsaturated fatty acids by cytochrome P450 monooxygenates

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Role of PGI2 and epoxyeicosatrienoic acids in relaxation of bovine coronary arteries to arachidonic acid

1993 • 134 citations

Metabolism of Epoxyeicosatrienoic Acids by Cytosolic Epoxide Hydrolase: Substrate Structural Determinants of Asymmetric Catalysis

1995 • 126 citations

Cytochrome P450‐dependent effects of bradykinin in the rat heart

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1990 • 110 citations

Two mechanisms mediate relaxation by bradykinin of pig coronary artery: NO-dependent and -independent responses

1991 • 97 citations

14,15-Epoxyeicosatrienoic acid metabolism in endothelial cells.

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Identification of Arachidonate P-450 Metabolites in Human Platelet Phospholipids

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Metabolism of Phospholipids in Peripheral Nerve from Rats with Chronic Streptozotocin‐induced Diabetes Increased Turnover of Phosphatidylinositol‐4,5‐Bisphosphate

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Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta

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Presence of cytochrome P-450-dependent monooxygenase in intimal cells of the hog aorta.

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Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct.

1989 • 66 citations

Selective inhibition by barbiturates of the synthesis of endothelium‐derived hyperpolarizing factor in the rabbit carotid artery

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Conversion of 15-hydroxyeicosatetraenoic acid to 11-hydroxyhexadecatrienoic acid by endothelial cells

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Epoxygenase metabolites of docosahexaenoic and eicosapentaenoic acids inhibit platelet aggregation at concentrations below those affecting thromboxane synthesis.

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Arachidonic acid availability and prostacyclin production by cultured human endothelial cells.

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Effect of Protein Kinase C Modulators on 14,15‐Epoxyeicosatrienoic Acid Incorporation into Astroglial Phospholipids

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Oxidation of 5,8,11,14,17-eicosapentaenoic acid by hepatic and renal microsomes

1988 • 41 citations

Epoxyeicosatrienoic acid stimulates ADP-ribosylation of a 52 kDa protein in rat liver cytosol

1992 • 36 citations

Formation and release of a peroxisome-dependent arachidonic acid metabolite by human skin fibroblasts.

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Relaxation of porcine coronary artery to bradykinin. Role of arachidonic acid.

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Identification of arachidonate epoxides/diols by capillary chromatography-mass spectrometry.

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15-HETE: Selective incorporation into inositol phospholipids of MDCK cells

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Optimization of epoxyeicosatrienoic acid syntheses to test their effects on cerebral blood flow in vivo

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Lipoxins A4 and B4 dilate cerebral arterioles of newborn pigs

1989 • 18 citations