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Adaptive immune response of Vγ2Vδ2 T cells: a new paradigm

Data up to Jan 2025

Published2003
Citations68
References61

Total Citations Per Year

Abstract

References (61)

Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells

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Lymphocytes bearing antigen-specific γδ T-cell receptors accumulate in human infectious disease lesions

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Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

2002 • 584 citations

Intraepithelial lymphocytes: exploring the Third Way in immunology

2001 • 481 citations

MICA Engagement by Human Vγ2Vδ2 T Cells Enhances Their Antigen-Dependent Effector Function

2001 • 394 citations

Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea

1999 • 368 citations

Adaptive Immune Response of Vγ2Vδ2 + T Cells During Mycobacterial Infections

2002 • 368 citations

Self-Recognition of Cd1 by γ/δ T Cells

2000 • 367 citations

Biological Insights into TCRγδ+ and TCRαβ+ Intraepithelial Lymphocytes Provided by Serial Analysis of Gene Expression (SAGE)

2001 • 267 citations

T Cell Antigen Receptor Engagement and Specificity in the Recognition of Stress-Inducible MHC Class I-Related Chains by Human Epithelial γδ T Cells

2002 • 244 citations

Immunoregulatory Functions of γδ T Cells

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Bacille Calmette-Guérin vaccination enhances human gamma delta T cell responsiveness to mycobacteria suggestive of a memory-like phenotype.

1998 • 185 citations

A Population of Murine γδ T Cells That Recognize an Inducible MHC Class Ib Molecule

2000 • 183 citations

Attributes of γδ intraepithelial lymphocytes as suggested by their transcriptional profile

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Antigen recognition by human γδ T cells: pattern recognition by the adaptive immune system

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Increased γδ T cells in acute Plasmodium falciparum malaria

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Predominant activation and expansion of V gamma 9-bearing gamma delta T cells in vivo as well as in vitro in Salmonella infection.

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Patterns of Chemokine Receptor Expression on Peripheral Blood γδ T Lymphocytes: Strong Expression of CCR5 Is a Selective Feature of Vδ2/Vγ9 γδ T Cells

2002 • 152 citations

Antibacterial effect of human Vγ2Vδ2 T cells in vivo

2001 • 150 citations

Single-cell cytokine analysis of gamma delta T cell responses to nonpeptide mycobacterial antigens.

1997 • 141 citations

Vγ9 / Vδ2 T lymphocytes reduce the viability of intracellularMycobacterium tuberculosis

2000 • 134 citations

Lymphocytes bearing the γδ T cell receptor in acute Brucella melitensis infection

1993 • 125 citations

Distinct Structure and Signaling Potential of the γδTCR Complex

2002 • 125 citations

Activation of C-C beta-chemokines in human peripheral blood gammadelta T cells by isopentenyl pyrophosphate and regulation by cytokines.

2000 • 115 citations

Lack of CD27−CD45RA−Vγ9Vδ2+ T Cell Effectors in Immunocompromised Hosts and During Active Pulmonary Tuberculosis

2002 • 115 citations

Transient increase in circulating gamma/delta T cells during Plasmodium vivax malarial paroxysms.

1994 • 114 citations

Control of natural killer cell-mediated innate resistance against the intracellular pathogen Listeria monocytogenes by gamma/delta T lymphocytes

1996 • 111 citations

Expansion of Vγ9Vδ2 T Cells Is Triggered byFrancisella tularensis-Derived Phosphoantigens in Tularemia but Not after Tularemia Vaccination

1998 • 111 citations

T-Lymphocytes with γδ + Vδ2+ Antigen Receptors Are Present in Increased Proportions in a Fraction of Patients with Tuberculosis or with Sarcoidosis

1993 • 105 citations

Lymphocytes bearing the gamma delta T-cell receptor in acute toxoplasmosis.

1992 • 98 citations

In vivo and in vitro activation and expansion of gammadelta T cells during Listeria monocytogenes infection in humans

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Antigen Recognition and Immunomodulation by γδ T Cells in Bovine Tuberculosis

2001 • 81 citations

Human Vγ2Vδ2 T Cells Produce IFN-γ and TNF-α with an On/Off/On Cycling Pattern in Response to Live Bacterial Products

2001 • 80 citations

Predominant expansion of V gamma 9/V delta 2 T cells in a tularemia patient

1992 • 74 citations

IL-12-mediated NKRP1A up-regulation and consequent enhancement of endothelial transmigration of V delta 2+ TCR gamma delta+ T lymphocytes from healthy donors and multiple sclerosis patients.

1999 • 73 citations

Increase of gamma/delta T cells in hospital workers who are in close contact with tuberculosis patients

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Increased Proportions of Peripheral Blood γδ T Cells in Patients with Pulmonary Tuberculosis

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Transendothelial chemotaxis of human αβ and γδ T lymphocytes to chemokines

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γδ T cells and the immune response in visceral leishmaniasis

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Lymphocytosis ofγ/δT Cells in Human Ehrlichiosis

1995 • 63 citations

In vitro stimulation with a non‐peptidic alkylphosphate expands cells expressing Vγ2‐Jγ1.2/Vδ2 T‐cell receptors

2001 • 62 citations

Vγ9Vδ2 T Cells Impair Intracellular Multiplication ofBrucella suisin Autologous Monocytes Through Soluble Factor Release and Contact-Dependent Cytotoxic Effect

2000 • 61 citations

Antigen-reactive gamma delta T cells in human leishmaniasis.

1993 • 59 citations

An αβ T‐cell‐independent immunoprotective response towards gut coccidia is supported by γδ cells

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Conserved T-cell receptor repertoire in simian immunodeficiency virus-infected rhesus monkeys.

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γδ T Cell-Deficient Mice Have a Down-Regulated CD8+ T Cell Immune Response AgainstEncephalitozoon cuniculiInfection

2001 • 51 citations

The proportion of circulatingγδT cells increases after the first week of onset of tularaemia and remains elevated for more than a year

2000 • 50 citations

Vdelta1 and Vdelta2 gammadelta T cells express distinct surface markers and might be developmentally distinct lineages.

2001 • 49 citations

Acute Human Immunodeficiency Virus Replication Causes a Rapid and Persistent Impairment of Vγ9Vδ2 T Cells in Chronically Infected Patients Undergoing Structured Treatment Interruption

2002 • 44 citations

Transendothelial Migratory Pathways of Vδ1+TCRγδ+ and Vδ2+TCRγδ+ T Lymphocytes from Healthy Donors and Multiple Sclerosis Patients: Involvement of Phosphatidylinositol 3 Kinase and Calcium Calmodulin-Dependent Kinase II

2002 • 41 citations

Functional and Structural Similarity of Vγ9Vδ2 T Cells in Humans and Aotus Monkeys, a Primate Infection Model for Plasmodium falciparum Malaria

2001 • 38 citations

Canarypox Vaccines Induce Antigen‐Specific Human γδ T Cells Capable of Interferon‐γ Production

2001 • 34 citations

Predominance of Vγ9/Vδ2 T Lymphocytes in the Cerebrospinal Fluid of Children with Tuberculous Meningitis: Reversal after Chemotherapy

1999 • 33 citations

γδ T cell receptor repertoire in blood and colonic mucosa of rhesus macaques

2000 • 31 citations

γδ T lymphocytes and proinflammatory cytokines in bacterial meningitis

1994 • 28 citations

Delayed expansion of Vδ2+ and Vδ1+ γδ T cells after acute Plasmodium falciparum and Plasmodium vivax malaria

1996 • 27 citations

The Number and Proportion of V 9V 2 T Cells Rise Significantly in the Peripheral Blood of Patients After the Onset of Acute Coxiella burnetii Infection

1997 • 25 citations

Vγ2 TCR Repertoire Overlap in Different Anatomical Compartments of Healthy, Unrelated Rhesus Macaques

2001 • 15 citations

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Adaptive immune response of Vγ2Vδ2 T cells: a new paradigm (2003) – Trends in Immunology | Metascience Observatory Explorer