Telomerase in Yeast

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1989 • 1,607 citations

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1989 • 1,509 citations

The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1987 • 1,127 citations

An alternative pathway for yeast telomere maintenance rescues est1− senescence

1993 • 916 citations

A mutant with a defect in telomere elongation leads to senescence in yeast

1989 • 905 citations

TLC1 : Template RNA Component of Saccharomyces cerevisiae Telomerase

1994 • 727 citations

THE MOLECULAR STRUCTURE OF CENTROMERES AND TELOMERES

1984 • 693 citations

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1990 • 632 citations

DNA sequences of telomeres maintained in yeast

1984 • 552 citations

TELOMERASES

1992 • 531 citations

Functional Evidence for an RNA Template in Telomerase

1990 • 392 citations

Runaway telomere elongation caused by telomerase RNA gene mutations

1995 • 338 citations

Telomeres: No end in sight

1994 • 322 citations

Unusual DNA sequences associated with the ends of yeast chromosomes

1984 • 236 citations

Developmentally programmed healing of chromosomes by telomerase in tetrahymena

1991 • 204 citations

Telomerase RNAs of different ciliates have a common secondary structure and a permuted template.

1994 • 192 citations

Telomerase primer specificity and chromosome healing

1991 • 174 citations

Telomere terminal transferase activity in the hypotrichous ciliateOxytricha novaand a model for replication of the ends of linear DNA molecules

1988 • 171 citations

Identification of a nonprocessive telomerase activity from mouse cells.

1993 • 164 citations

Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation.

1993 • 157 citations

Telomere telomere recombination provides an express pathway for telomere acquisition

1990 • 146 citations

Telomerase activity in germline and embryonic cells of Xenopus.

1994 • 130 citations

Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers.

1989 • 118 citations

An in vitro assay for saccharomyces telomerase requires EST1

1995 • 111 citations

Sequence-specific DNA primer effects on telomerase polymerization activity.

1993 • 102 citations

Altering specific telomerase RNA template residues affects active site function.

1995 • 95 citations

Sequencing of Saccharomyces telomeres cloned using T4 DNA polymerase reveals two domains.

1990 • 94 citations