Endothelial and macrophage upregulation of urokinase receptor expression in human renal cell carcinoma

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

The use of avidin-biotin interaction in immunoenzymatic techniques.

1979 • 1,734 citations

Biology and biochemistry of proteinases in tumor invasion

1993 • 1,264 citations

Angiostatin induces and sustains dormancy of human primary tumors in mice

1996 • 1,193 citations

The origin and function of tumor-associated macrophages

1992 • 1,081 citations

Antibodies to plasminogen activator inhibit human tumor metastasis

1983 • 651 citations

Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells

1991 • 626 citations

Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.

1990 • 624 citations

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

1991 • 578 citations

Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas.

1993 • 564 citations

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

1990 • 452 citations

Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas.

1991 • 440 citations

Urokinase and urokinase receptor: A paracrine/autocrine system regulating cell migration and invasiveness

1993 • 402 citations

Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages.

1984 • 366 citations

Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis

1994 • 354 citations

Plasminogen Activation Initiated by Single-chain Urokinase-type Plasminogen Activator

1989 • 341 citations

Upregulation of urokinase receptor expression on migrating endothelial cells

1993 • 277 citations

The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator.

1991 • 256 citations

Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine kidney epithelial cells.

1992 • 219 citations

Cell‐induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH₂‐terminal domain of the urokinase receptor

1991 • 194 citations

Receptor for urokinase is present in tumor-associated macrophages in ductal breast carcinoma.

1993 • 192 citations

Urokinase‐type plasminogen activator mediates basic fibroblast growth factor‐induced bovine endothelial cell migration independent of its proteolytic activity

1992 • 183 citations

Plasminogen activator dependent pathways inthe dissemination of human tumor cells in the chick embryo

1988 • 181 citations

Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans.

1991 • 179 citations

Sites of synthesis of urokinase and tissue-type plasminogen activators in the murine kidney.

1991 • 161 citations

The urokinase receptor is expressed in invasive breast cancer but not in normal breast tissue.

1994 • 153 citations

Plasminogen activators, their inhibitors, and urokinase receptor emerge in late stages of melanocytic tumor progression.

1994 • 150 citations

Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancer

1994 • 107 citations

Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography: comparison with urokinase levels.

1993 • 102 citations

IFN-gamma, tumor necrosis factor-alpha, and urokinase regulate the expression of urokinase receptors on human monocytes.

1988 • 101 citations

Expression of c-ets-1, collagenase 1, and urokinase-type plasminogen activator genes in lung carcinomas.

1995 • 101 citations

cDNA for Mo3, a monocyte activation antigen, encodes the human receptor for urokinase plasminogen activator.

1992 • 89 citations

Calcitonin stimulates plasminogen activator in porcine renal tubular cells: LLC-PK1.

1981 • 86 citations

Constitutive expression and modulation of the functional thrombin receptor in the human kidney.

1995 • 46 citations

Renal pathology in biopsy : light, electron, and immunofluorescent microscopy and clinical aspects

1978 • 43 citations

Modulation of urokinase and urokinase receptor gene expression in human renal cell carcinoma.

1995 • 34 citations

Increased urokinase receptor levels in human gastrointestinal neoplasia and related liver metastases.

1993 • 26 citations