Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography: comparison with urokinase levels.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase.

1985 • 731 citations

Antibodies to plasminogen activator inhibit human tumor metastasis

1983 • 651 citations

Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors

1987 • 625 citations

Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.

1992 • 571 citations

The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases.

1987 • 479 citations

The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type.

1986 • 466 citations

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.

1985 • 450 citations

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells.

1987 • 378 citations

Autocrine saturation of pro-urokinase receptors on human A431 cells

1986 • 361 citations

Plasminogen Activation Initiated by Single-chain Urokinase-type Plasminogen Activator

1989 • 341 citations

Prognostic value of urokinase-type plasminogen activator in 671 primary breast cancer patients.

1992 • 239 citations

Modulation of metastatic potential by cell surface urokinase of murine melanoma cells.

1988 • 223 citations

Surface receptors for urokinase plasminogen activator

1988 • 222 citations

Nuclear structure in cancer tissues.

1957 • 222 citations

In vivo paracrine interaction between urokinase and its receptor: effect on tumor cell invasion.

1991 • 216 citations

Content and characterization of plasminogen activators in human lung tumors and normal lung tissue.

1980 • 179 citations

The Receptor-Binding Sequence of Urokinase

1987 • 167 citations

QUANTITATION AND IMMUNOCYTOCHEMICAL LOCALIZATION OF HUMAN SKIN COLLAGENASE IN BASAL CELL CARCINOMA

1977 • 166 citations

Regulation of urokinase receptors in monocytelike U937 cells by phorbol ester phorbol myristate acetate.

1989 • 142 citations

Application of Quantitative Autoradiographic Measurements in Experimental Brain Tumor Models

1981 • 138 citations

Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas.

1987 • 136 citations

Role of the urokinase receptor in facilitating extracellular matrix invasion by cultured colon cancer.

1991 • 123 citations

Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta

1988 • 118 citations

Plasminogen activator secretion of human tumors in short-term organ culture, including a comparison of primary and metastatic colon tumors.

1983 • 116 citations

Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion.

1989 • 99 citations

Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line.

1989 • 91 citations

Examination of the role of the urokinase receptor in human colon cancer mediated laminin degradation.

1989 • 90 citations

Modulation of urokinase plasminogen activator gene expression during the transition from quiescent to proliferative state in normal mouse cells.

1986 • 83 citations

Improved Medium for Extraction of Plasminogen Activator from Tissue

1982 • 65 citations

A soluble, ligand binding mutant of the human urokinase plasminogen activator receptor

1991 • 65 citations

Modulation of plasminogen activator in rodent mammary tumors by hormones and other effectors.

1983 • 57 citations

Binding of urokinase to specific receptor sites on human breast cancer membranes

1987 • 52 citations

Regulation by epidermal growth factor of human squamous cell carcinoma plasminogen activator-mediated proteolysis of extracellular matrix.

1989 • 40 citations

Heterogeneity of fibroblast response in host‐tumor cell‐cell interactions in metastatic tumors

1987 • 23 citations

Induction of Proteases and Protease Inhibitors by Growth Factors

1990 • 9 citations