Reduced intracellular oxidative metabolism promotes firm adhesion of human polymorphonuclear leukocytes to vascular endothelium under flow conditions

Leukocyte-endothelial adhesion molecules

1994 • 2,567 citations

Antioxidant and redox regulation of gene transcription

1996 • 1,999 citations

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

1983 • 1,808 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 • 1,330 citations

Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors

1989 • 1,135 citations

Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro.

1989 • 1,115 citations

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.

1993 • 1,079 citations

Adhesion molecules and inflammatory injury

1994 • 1,023 citations

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

1986 • 733 citations

Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance.

1995 • 660 citations

Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine

1979 • 637 citations

A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen.

1993 • 523 citations

Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro.

1991 • 439 citations

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion.

1991 • 406 citations

Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins.

1994 • 391 citations

Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha.

1992 • 383 citations

Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1.

1991 • 359 citations

Effect of phorbol myristate acetate on the oxidative metabolism of human polymorphonuclear leukocytes

1976 • 357 citations

Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells

1992 • 355 citations

Induction of Interleukin 6 (IL-6) by Hypoxia in Vascular Cells

1995 • 348 citations

Hypoxic induction of interleukin-8 gene expression in human endothelial cells.

1994 • 346 citations

Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface.

1992 • 341 citations

Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium.

1988 • 333 citations

Endothelial-leukocyte adhesion molecule-1-dependent and leukocyte (CD11/CD18)-dependent mechanisms contribute to polymorphonuclear leukocyte adhesion to cytokine-activated human vascular endothelium.

1989 • 288 citations

Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils.

1993 • 287 citations

Neutrophil rolling altered by inhibition of L-selectin shedding in vitro

1996 • 285 citations

Transient adhesion of neutrophils to endothelium.

1989 • 279 citations

Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation.

1996 • 276 citations

Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway.

1995 • 265 citations

Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens.

1990 • 263 citations

Sequential observation of micrometastasis formation by bacterial lacZ gene-tagged Lewis lung carcinoma cells

1997 • 258 citations

Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands.

1989 • 204 citations

Increased PMN adherence on endothelial cells after hypoxia: involvement of PAF, CD18/CD11b, and ICAM-1

1993 • 189 citations

Granulocyte-macrophage colony-stimulating factor induces the expression of the CD11b surface adhesion molecule on human granulocytes in vivo

1988 • 141 citations

Inhibition of HIV progression by dithiocarb

1990 • 126 citations

Transcriptional up-regulation of intracellular adhesion molecule-1 in human endothelial cells by the antioxidant pyrrolidine dithiocarbamate involves the activation of activating protein-1.

1996 • 85 citations

Human neutrophils release the Leu-8 lymph node homing receptor during cell activation

1990 • 80 citations

Dynamics of neutrophil rolling over stimulated endothelium in vitro

1994 • 70 citations

Hypoxia enhances stimulus-dependent induction of E-selectin on aortic endothelial cells.

1996 • 68 citations

Antioxidant effect of diethyldithiocarbamate on microsomal lipid peroxidation assessed by low‐level chemiluminescence and alkane production

1983 • 60 citations

Antioxidant capacity of diethyldithiocarbamate in a metal independent lipid peroxidative process

1989 • 57 citations

Regulation of integrin-mediated myeloid cell adhesion to fibronectin: influence of disulfide reducing agents, divalent cations and phorbol ester.

1993 • 54 citations

Characterization of a hypoxia-responsive adhesion molecule for leukocytes on human endothelial cells.

1995 • 42 citations

Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways

1995 • 34 citations

Matrix protein regulation of PMN oxidative metabolism during ischemia

1994 • 33 citations

Sulfhydryl reducing agents promote neutrophil adherence without increasing surface expression of CD11bCD18 (Mac-1, Mol)

1989 • 31 citations

THE EFFECTS OF THE PROTRACTED ADMINISTRATION OF THE CHELATING AGENT, SODIUM DIETHYLDITHIOCARBAMATE (DITHIOCARB)

1967 • 31 citations

Regulation of polymorphonuclear leukocyte cytokine receptor expression: the role of altered oxygen tensions and matrix proteins.

1996 • 22 citations

Regulation of polymorphonuclear neutrophil CD16 and CD11b/CD18 expression by matrix proteins during hypoxia is VLA-5, VLA-6 dependent.

1995 • 22 citations

Cell adhesion and human disease

1996 • 20 citations

Leukocyte and Endothelial Adhesion Molecules in Ischaemia/Reperfusion Injuries

2007 • 11 citations