Amperozide, a 5-HT2 antagonist, attenuates craving for cocaine by rats

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

1989 • 1,313 citations

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

1980 • 736 citations

New concepts in cocaine addiction: The dopamine depletion hypothesis

1985 • 608 citations

Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats

1989 • 562 citations

Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.

1977 • 490 citations

Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats

1982 • 451 citations

Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.

1985 • 444 citations

Comparative studies of various amphetamine analogues demonstrating different interactions with the metabolism of the catecholamines in the brain

1971 • 405 citations

Inhibition of the uptake of tritiated 5-hydroxytryptamine in brain tissue

1969 • 321 citations

Basal extracellular dopamine is decreased in the rat nucleus accumbens during abstinence from chronic cocaine

1991 • 265 citations

CNS stimulants: two distinct mechanisms of action for amphetamine-like drugs

1983 • 203 citations

Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat

1991 • 172 citations

Psychopharmacology of Alcohol

1978 • 152 citations

Comparison of inhibition of monoamine uptake by cocaine, methylphenidate and amphetamine.

1978 • 131 citations

Binding of [³H]SCH23390 in Rat Brain: Regional Distribution and Effects of Assay Conditions and GTP Suggest Interactions at a D₁‐Like Dopamine Receptor

1985 • 116 citations

Buprenorphine and naltrexone effects on cocaine self-administration by rhesus monkeys.

1990 • 103 citations

Receptor binding properties of amperozide

1990 • 68 citations

Ritanserin, a new therapeutic approach for drug abuse. Part 1: Effects on alcohol

1991 • 67 citations

Effects of amperozide in schizophrenia

1991 • 59 citations

Bromocriptine produces decreases in cocaine self-administration in the rat.

1990 • 59 citations

Amperozide, a Novel Antipsychotic Drug, Inhibits the Ability of d‐Amphetamine to Increase Dopamine Release In Vivo in Rat Striatum and Nucleus Accumbens

1992 • 56 citations

Selective reduction by the 5-HT antagonist amperozide of alcohol preference induced in rats by systemic cyanamide

1992 • 55 citations

Amperozide – a new putatively antipsychotic drug with a limbic mode of action on dopamine mediated behaviour

1990 • 51 citations

Novel Antipsychotic Drugs

1993 • 48 citations

5-HT2 receptor blockade by amperozide suppresses ethanol drinking in genetically preferring rats

1993 • 46 citations

In vivo voltammetric studies on release mechanisms for cocaine with γ-butyrolactone

1991 • 44 citations

Irreversible suppression of alcohol drinking in cyanamide-treated rats after sustained delivery of the 5-HT2 antagonist amperozide

1993 • 39 citations

Failure of the 5-HT2 receptor antagonist, ritanserin, to alter preference for alcohol in drinking rats

1993 • 35 citations

Effect of amperozide on rat cortical 5-HT2 and striatal and limbic dopamine D2 receptor occupancy: Implications for antipsychotic action

1992 • 34 citations

Ritanserin, a new therapeutic approach for drug abuse. Part 2: Effects on cocaine

1992 • 29 citations

Effect of amperozide on the synthesis and turnover of monoamines in rat brain

1990 • 26 citations

Amperozide and conditioned behaviour in rats: potentiation by classical neuroleptics and α‐methylparatyrosine

1990 • 20 citations

Amperozide, a putative anti-psychotic drug: Uptake inhibition and release of dopamine in the rat brain

1990 • 16 citations

Species-Dependent Responsiveness to Nonamphetamine Central Stimulants

1979 • 14 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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