Effects of σ1 receptor agonist SA4503 and neuroactive steroids on performance in a radial arm maze task in rats

Neuroactive steroids

1992 • 1,260 citations

Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

1996 • 880 citations

Sigma receptors: biology and function.

1990 • 799 citations

A proposal for the classification of sigma binding sites

1992 • 743 citations

Steroid Binding at σ Receptors Suggests a Link Between Endocrine, Nervous, and Immune Systems

1988 • 531 citations

Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor.

1991 • 521 citations

The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor

1990 • 433 citations

Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus.

1995 • 426 citations

Neurosteroids: Deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus

1997 • 299 citations

Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors

1996 • 296 citations

Sigma1 (σ1) receptor agonists and neurosteroids attenuate β25–35-amyloid peptide-induced amnesia in mice through a common mechanism

1998 • 280 citations

Dehydroepiandrosterone and its sulfate enhance memory retention in mice

1988 • 232 citations

N-methyl-D-aspartate-induced neuronal activation is selectively modulated by σ receptors

1990 • 225 citations

Behavioral evidence for a modulating role of σ ligands in memory processes. I. Attenuation of dizocilpine (MK-801)-induced amnesia

1994 • 211 citations

Neuroprotective and anti-amnesic potentials of sigma (σ) receptor ligands

1997 • 209 citations

Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice

1987 • 199 citations

Binding properties of SA4503, a novel and selective σ1 receptor agonist

1996 • 186 citations

In vivo electrophysiological evidence for a selective modulation of N-methyl-D-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by sigma ligands.

1992 • 173 citations

Cloning and Characterization of a Mouse σ₁ Receptor

1998 • 149 citations

Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells

1991 • 133 citations

Dehydroepiandrosterone sulfate attenuates dizocilpine-induced learning impairment in mice via σ1-receptors

1997 • 125 citations

σ1 Receptor subtype is involved in the relief of behavioral despair in the mouse forced swimming test

1996 • 119 citations

Nitric oxide synthase inhibitors impair reference memory formation in a radial arm maze task in rats

1998 • 115 citations

The role of nitric oxide in dizocilpine-induced impairment of spontaneous alternation behavior in mice.

1996 • 114 citations

Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in mice

1996 • 110 citations

Increase in extracellular acetylcholine level by sigma ligands in rat frontal cortex.

1993 • 99 citations

Modulation by sigma ligands of N-methyl-D-aspartate-induced [3H]noradrenaline release in the rat hippocampus: G-protein dependency

1992 • 70 citations

Beneficial effects of sigma agonists on the age-related learning impairment in the senescence-accelerated mouse (SAM)

1996 • 68 citations

Ameliorating effects of σ receptor ligands on the impairment of passive avoidance tasks in mice: involvement in the central acetylcholinergic system

1994 • 65 citations

JO1784, a novel σ ligand, potentiates [3H]acetylcholine release from rat hippocampal slices

1991 • 64 citations

Involvement of σ1 receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats

1995 • 62 citations

Pregnenolone sulfate potentiation of NMDA-mediated increases in intracellular calcium in cultured chick cortical neurons

1995 • 56 citations

Behavioral evidence for a modulating role of σ ligands in memory processes. II. Reversion of carbon monoxide-induced amnesia

1994 • 50 citations

Low dose of 1,3-di(2-tolyl)guanidine (DTG) attenuates MK-801-induced spatial working memory impairment in mice

1994 • 40 citations

Relationship between Sigma-like site and progesterone-binding site of adult male rat liver microsomes

1994 • 40 citations

The effects of pregnenolone sulfate and ethylestrenol on retention of a passive avoidance task

1995 • 40 citations

σ Receptor ligands (+)-SKF10,047 and SA4503 improve dizocilpine-induced spatial memory deficits in rats

1998 • 39 citations

Protein Phosphorylation and Calcium Uptake into Rat Forebrain Synaptosomes: Modulation by the σ Ligand, 1,3‐Ditolylguanidine

1997 • 37 citations