Commensal bacteria as targets in Crohn's disease

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

Cloning the Differences Between Two Complex Genomes

1993 • 1,301 citations

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

1996 • 1,227 citations

Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats.

1996 • 795 citations

Handbook of Mucosal Immunology

1994 • 711 citations

Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease.

1997 • 487 citations

Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance.

1996 • 444 citations

CD4+ T Cells Reactive to Enteric Bacterial Antigens in Spontaneously Colitic C3H/HeJBir Mice: Increased T Helper Cell Type 1 Response and Ability to Transfer Disease

1998 • 393 citations

Mucins and inflammatory bowel disease

2000 • 316 citations

CD4+ T-cell subsets in autoimmunity

1997 • 249 citations

Identification of a novel bacterial sequence associated with Crohn's disease

2000 • 216 citations

Spontaneously colitic C3H/HeJBir mice demonstrate selective antibody reactivity to antigens of the enteric bacterial flora.

1997 • 158 citations

CD4+ T cell down-regulation in human intestinal mucosa: evidence for intestinal tolerance to luminal bacterial antigens.

1997 • 146 citations

Patients with active Crohn's disease have elevated serum antibodies to antigens of seven enteric bacterial pathogens.

1984 • 109 citations

An immunocytochemical search for infectious agents in Crohn's disease.

1993 • 103 citations

Patients with active Crohn's disease have elevated serum antibodies to antigens of seven enteric bacterial pathogens

1984 • 95 citations

Immunology of inflammatory bowel disease

1996 • 65 citations

Immunology of inflammatory bowel disease

2000 • 25 citations