Metalloproteinases in endochondral bone formation: Appearance of tissue inhibitor-resistant metalloproteinases

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1980 • 1,991 citations

The spread of tumors in the human body

1935 • 487 citations

A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

1979 • 350 citations

Isolations of a Cartilage Factor That Inhibits Tumor Neovascularization

1976 • 308 citations

Cartilage ultrastructure after high pressure freezing, freeze substitution, and low temperature embedding. I. Chondrocyte ultrastructure--implications for the theories of mineralization and vascular invasion.

1984 • 225 citations

Electron microscopic demonstration of proteoglycans in guinea pig epiphyseal cartilage

1973 • 189 citations

Human Skin Fibroblast Collagenase: Interaction with Substrate and Inhibitor

1985 • 167 citations

Effect of proteoglycans on in vitro hydroxyapatite formation

1979 • 165 citations

Role of proteoglycans in endochondral ossification: immunofluorescent localization of link protein and proteoglycan monomer in bovine fetal epiphyseal growth plate.

1982 • 159 citations

Heterogeneity of Proteochondroitin Sulfates Produced by Chondrocytes at Different Stages of Cytodifferentiation

1974 • 144 citations

Tumor Cell Collagenase and Its Inhibition by a Cartilage-Derived Protease Inhibitor

1977 • 143 citations

Protein- Polysaccharide Loss during Endochondral Ossification: Immunochemical Evidence

1966 • 140 citations

EVIDENCE FOR CHANGES IN PROTEIN POLYSACCHARIDE ASSOCIATED WITH THE ONSET OF CALCIFICATION IN CARTILAGE

1968 • 116 citations

Inhibition of calcium phosphate mineral growth by proteoglycan aggregate fractions in a synthetic lymph

1973 • 114 citations

A rapid in situ deoxyribonucleic acid assay for determining cell number in culture and tissue

1982 • 109 citations

THE SURFACE CHEMISTRY OF BONE

1951 • 107 citations

Cellular Interactions

1982 • 97 citations

Induction of the synthesis of latent collagenase and latent neutral protease in chondrocytes by a factor synthesized by activated macrophages

1980 • 90 citations

Proteinase inhibitors of bovine nasal cartilage

1978 • 90 citations

Development of the tibiotarsus in the chick embryo: biosynthetic activities of histologically distinct regions

1979 • 86 citations

An improved assay for proteases and polysaccharidases employing a cartilage proteoglycan substrate entrapped in polyacrylamide particles

1980 • 83 citations

Isolation of a Protease Inhibitor from Tissues Resistant to Tumor Invasion

1977 • 66 citations

Two latent metalloproteases of human articular cartilage that digest proteoglycan.

1984 • 66 citations

A Correlation between Synthetic Activities for Matrix Macromolecules and Specific Stages of Cytodifferentiation in Developing Cartilage

1974 • 57 citations

Neutral proteinases from articular chondrocytes in culture. 2. Metal-dependent latent neutral proteoglycanase, and inhibitory activity

1981 • 53 citations

Type I procollagen N-proteinase from whole chick embryos. Cleavage of a homotrimer of pro-alpha 1(I) chains and the requirement for procollagen with a triple-helical conformation.

1985 • 49 citations

Formation of osteoclasts from blood monocytes during 1 alpha-OH Vit D-stimulated bone resorption in mice.

1981 • 48 citations

Proteolytic degradation of ossifying cartilage matrix and the removal of acid mucopolysaccharides prior to bone formation

1967 • 45 citations

A light and electron microscopic study of the region of cartilage resorption in the embryonic chick femur

1980 • 41 citations

Vascular invasion of cartilage: Correlation of morphology with lysozyme, glycosaminoglycans, protease, and protease-inhibitory activity during endochondral bone development

1981 • 41 citations

The properties of the neutral proteinase released by primary chondrocyte cultures and its action on proteoglycan aggregate

1982 • 36 citations

Production of collagenase inhibitor by the growth cartilage of embryonic chick bone: isolation and partial characterization

1980 • 26 citations

Characterization of latent and active forms of cartilage proteinases produced by normal immature rabbit articular cartilage in tissue culture

1983 • 16 citations

Cartilage-degrading neutral proteinase secreted by Yoshida sarcoma cells. Purification and properties.

1984 • 9 citations