Two latent metalloproteases of human articular cartilage that digest proteoglycan.

A modified uronic acid carbazole reaction

1962 • 6,191 citations

A Direct Spectrophotometric Microassay for Sulfated Glycosaminoglycans in Cartilage Cultures

1982 • 1,345 citations

COLLAGENOLYTIC ACTIVITY IN AMPHIBIAN TISSUES: A TISSUE CULTURE ASSAY

1962 • 1,275 citations

Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components

1983 • 222 citations

The molecular weight and properties of a neutral metallo-endopeptidase from rabbit kidney brush border

1974 • 185 citations

Collagenase and collagenolytic activity in human osteoarthritic cartilage

1983 • 168 citations

Neutral proteases capable of proteoglycan digesting activity in osteoarthritic and normal human articular cartilage

1984 • 166 citations

Metalloproteases of human articular cartilage that digest cartilage proteoglycan at neutral and acid pH.

1976 • 160 citations

Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin

1981 • 138 citations

Synthesis of collagenase and neutral proteases by articular chondrocytes: Stimulation by a macrophage-derived factor

1978 • 132 citations

Radiolabeling of proteins and viruses in vitro by acetylation with radioactive acetic anhydride.

1975 • 111 citations

Extraction of collagenase from the involuting rat uterus

1976 • 96 citations

Induction of the synthesis of latent collagenase and latent neutral protease in chondrocytes by a factor synthesized by activated macrophages

1980 • 90 citations

A precursor form of latent collagenase produced in a cell-free system with mRNA from rabbit synovial cells.

1981 • 88 citations

An improved assay for proteases and polysaccharidases employing a cartilage proteoglycan substrate entrapped in polyacrylamide particles

1980 • 83 citations

Neutral proteinases from articular chondrocytes in culture. 2. Metal-dependent latent neutral proteoglycanase, and inhibitory activity

1981 • 53 citations

Corneal collagenases: evidence for zinc metalloenzymes.

1973 • 47 citations

Further characterization of a neutral metalloprotease isolated from human articular cartilage

1982 • 46 citations

Metalloproteases from Penicillium caseicolum and P. roqueforti: Comparison of specificity and cemical characterization

1980 • 38 citations

The properties of the neutral proteinase released by primary chondrocyte cultures and its action on proteoglycan aggregate

1982 • 36 citations

Isolation and secretion of proteolytic enzymes from articular cartilage in organ culture

1981 • 4 citations