Quantitative light microscopic autoradiographic localization of α2-adrenoceptors in the human brain

A STUDY OF THE ADRENOTROPIC RECEPTORS

1948 • 2,856 citations

Presynaptic regulation of the release of catecholamines.

1980 • 1,483 citations

Regulation of noradrenaline release by presynaptic receptor systems

1977 • 1,482 citations

Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents

1984 • 719 citations

Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia

1982 • 677 citations

Quantitative receptor autoradiography using [3H]Ultrofilm: application to multiple benzodiazepine receptors

1982 • 529 citations

A radioautographic study of the efferent pathways of the nucleus locus coeruleus

1974 • 500 citations

UK-14,304, a potent and selective α2-agonist for the characterisation of α-adrenoceptor subtypes

1981 • 287 citations

beta-Adrenergic Receptor Subtypes: Properties, Distribution, and Regulation

1981 • 277 citations

Loss of pigmented dopamine-β-hydroxylase positive cells from locus coeruleus in senile dementia of alzheimer's type

1983 • 267 citations

Modulation of rat brain α- and β-adrenergic receptor populations by lesions of the dorsal noradrenergic bundle

1980 • 246 citations

Catecholamine innervation of the basal forebrain III. Olfactory bulb, anterior olfactory nuclei, olfactory tubercle and piriform cortex

1978 • 223 citations

Progressive Supranuclear Palsy

2005 • 218 citations

Human brainstem catecholamine neuronal anatomy as indicated by immunocytochemistry with antibodies to tyrosine hydroxylase

1983 • 213 citations

Quantitative receptor mapping by autoradiography: some current technical problems

1985 • 204 citations

Clonidine-induced inhibition of sympathetic nerve activity: No indication for a central presynaptic or an indirect sympathomimetic mode of action

1974 • 200 citations

The distribution of neocortical projection neurons in the locus coeruleus

1983 • 179 citations

The pathology of the human locus ceruleus.

1983 • 163 citations

Quantitative receptor autoradiography with tritium-labeled ligands: comparison of biochemical and densitometric measurements

1984 • 155 citations

Molecular characterization of α1- and α2-adrenoceptors

1991 • 153 citations

Studies on neurotransmitter receptor systems in neocortex and hippocampus in senile dementia of the Alzheimer-type

1984 • 129 citations

α1-adrenoceptors in the mammalian brain: similar pharmacology but different distribution in rodents and primates

1987 • 126 citations

Pathology of Parkinson's disease

1981 • 121 citations

Inhibition of neuronal uptake reduces the presynaptic effects of clonidine but not of α-methylnoradrenaline on the stimulation-evoked release of 3H-noradrenaline from rat occipital cortex slices

1980 • 111 citations

Adrenergic receptors in Parkinson's disease

1984 • 96 citations

Increased? 2;-adrenoceptor density in the frontal cortex of depressed suicide victims

1987 • 95 citations

α1- and α2-adrenoceptors in rat cerebral cortex: Effects of neonatal treatment with 6-hydroxydopamine

1982 • 86 citations

Biochemical Characterization of α‐Adrenergic Receptors in Human Brain and Changes in Alzheimer‐Type Dementia

1986 • 73 citations

Monoamine fluorescence histochemistry of human post mortem brain

1973 • 72 citations

The central modulatory effect of clonidine on the cardiodepressor reflex after suppression of synthesis and storage of noradrenaline

1975 • 71 citations

Distribution of α2-adrenergic receptors in the human brainstem: An autoradiographic study using [3H]p-aminoclonidine

1984 • 69 citations

Tyrosine hydroxylase immunohistochemistry in human brain

1979 • 66 citations

Presynaptic noradrenergic α-receptros and modulation of 3H-noradrenaline release from rat brain synaptosomes

1979 • 63 citations

?1- and ?2-Adrenoceptors in rat cerebral cortex: Effect of frontal lobotomy

1981 • 56 citations

Evidence for retrograde degeneration of epinephrine neurons in Alzheimer's disease

1988 • 52 citations

Quantitative analysis of rat brain α2-receptors discriminated by [3H]clonidine and [3H]rauwolscine

1984 • 43 citations

Characterization and Regional Distribution of α₂‐Adrenoceptors in Postmortem Human Brain Using the Full Agonist [³H]UK 14304

1989 • 42 citations

Distribution of adrenaline-synthesizing enzyme activity in the human brain

1979 • 40 citations

Binding of adrenergic ligands ([3H]clonidine and [3H]WB-4101) to multiple sites in human brain

1981 • 37 citations

α2-Adrenoceptors in human forebrain: autoradiographic visualization and biochemical parameters using the agonist [3H]UK-14304

1988 • 35 citations

Adrenergic receptors in frontal cortex in human brain

1985 • 33 citations

Phenylethanolamine N‐methyltransferase activity is decreased in Alzheimer's disease brains

1987 • 29 citations

Does clonidine alter anxiety in humans?

1982 • 28 citations

Regionally specific age-dependent decline in α2-adrenoceptors: An autoradiographic study in human brain

1991 • 27 citations

Pharmacological characterization of presynaptic alpha-adrenoceptors in the nucleus tractus solitarii and the cerebral cortex of the rat

1982 • 27 citations

Stereochemical requirements for activation and blockade of α1- and α2- adrenoceptors

1984 • 18 citations

A Highly Sensitive Assay for Phenylethanolamine N-Methyltransferase in Human Brain

1986 • 15 citations

[3H]clonidine binds at multiple high affinity states in human prefrontal cortex

1986 • 12 citations

Brain imaging — Techniques and applications

1990 • 11 citations

HTLV-I-associated meningitis

1988 • 10 citations

Progressive Supranuclear Palsy

2024 • 5 citations