Stereochemical requirements for activation and blockade of α1- and α2- adrenoceptors

Studies on the relationship between chemical constitution and physiological action

1933 • 437 citations

Evidence for more than one type of post-junctional α-Adrenoceptor

1982 • 399 citations

Pre- and postsynaptic effects of yohimbine stereoisomers on noradrenergic transmission in the pulmonary artery of the rabbit

1979 • 273 citations

Molecular geometry and adrenergic drug activity.

1974 • 146 citations

Adrenoceptors and catecholamine action

1981 • 111 citations

Quantum mechanical study of the conformational properties of phenethylamines of biochemical and medicinal interest

1972 • 105 citations

THE α‐ AND β‐ADRENOCEPTOR BLOCKING POTENCIES OF LABETALOL AND ITS INDIVIDUAL STEREOISOMERS IN ANAESTHETIZED DOGS AND IN ISOLATED TISSUES

1982 • 105 citations

Vascular effects of the stereoisomers of dobutamine.

1983 • 92 citations

Stereochemistry and biological activity of drugs

1984 • 69 citations

Differences in the applicability of the Easson-Stedman hypothesis to the α1- and α2-adrenergic effects of phenethylamines and imidazolines

1983 • 64 citations

The preferred conformations of ephedrine isomers and the nature of the alpha adrenergic receptor.

1968 • 44 citations

Absolute configuration of glycerol derivatives. 7. Enantiomers of 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]ethyl]-1,4-benzodioxane (WB-4101), a potent competitive .alpha.-adrenergic antagonist

1979 • 31 citations

Stereochemical requirements of alpha-2 adrenergic receptors.

1982 • 29 citations

Blockade of postjunctional vascular alpha 1- and alpha 2-adrenoceptors in pithed rat by the enantiomers of WB-4101

1983 • 25 citations

Stereochemical requirements of α2-adrenergic receptors for α-methyl substituted phenethylamines

1982 • 20 citations

Stereochemical studies on medicinal agents. 10. Role of chirality in .alpha.-adrenergic receptor blockage by (+)- and (-)-phenoxy benzamine hydrochloride

1971 • 17 citations

Alpha adrenoreceptors of rabbit aorta and stomach fundus.

1981 • 16 citations

Conformational requirements of alpha 2-adrenergic receptors.

1982 • 13 citations

α2-Adrenoceptor agonist properties of exo- and endo-isomers of 2-amino-6,7,dihydroxybenzo-norbornene designed as rigid catecholamines

1983 • 12 citations

Effects of pyroxamidine and guanethidine on contractile responses to field stimulation and to noradrenaline in the anococcygeus muscle and vas deferens of the rat

1979 • 7 citations

Differential blockade of pre- and postsynaptic α-adrenoceptors by the 2-R and 2-S enantiomers of WB4101

1981 • 6 citations