Colonic Secretion Mediated by Prostaglandin E2 and 5-Hydroxytryptamine May Contribute to Diarrhea due to Morphine Withdrawal in the Rat

Physiology of the Gastrointestinal Tract.

1982 • 1,635 citations

CLONIDINE BLOCKS ACUTE OPIATE-WITHDRAWAL SYMPTOMS

1978 • 705 citations

Stimulation of intestinal mucosal adenyl cyclase by cholera enterotoxin and prostaglandins

1971 • 614 citations

Vascular effects of ketanserin (R 41 468), a novel antagonist of 5-HT2 serotonergic receptors.

1981 • 511 citations

Intestinal absorption and secretion

1991 • 365 citations

Characteristics and function of opioids

1979 • 283 citations

Modification of Morphine Withdrawal by Drugs interacting with Humoral Mechanisms: Some Contradictions and their Interpretation

1972 • 233 citations

Formulation of a Morphine Implantation Pellet Suitable for Tolerance-Physical Dependence Studies in Mice

1970 • 223 citations

Relationship between hormonal activation of phosphatidylinositol hydrolysis, fluid secretion and calcium flux in the blowfly salivary gland

1979 • 193 citations

Mechanism of prostaglandin biosynthesis. I. Characterization and assay of bovine prostaglandin synthetase

1971 • 190 citations

Inhibition of phosphatidylinositol synthesis and the inactivation of calcium entry after prolonged exposure of the blowfly salivary gland to 5-hydroxytryptamine

1979 • 181 citations

Effects of clonidine on morphine withdrawal signs in the rat

1975 • 177 citations

Simultaneous Determination of Serotonin, 5‐Hydroxyindoleacetic Acid, 3,4‐Dihydroxyphenylacetic Acid and Homovanillic Acid by High Performance Liquid Chromatography with Electrochemical Detection

1982 • 141 citations

Saturation kinetics applied to in vitro effects of low prostaglandin E2 and F2α concentrations on ion transport across human jejunal mucosa

1980 • 133 citations

Psychic Disturbances in Adult Coeliac Disease

1982 • 132 citations

Morphine abstinence is associated with increased brain cyclic AMP

1975 • 130 citations

5-Hydroxytryptamine and cholera secretion: a histochemical and physiological study in cats.

1983 • 122 citations

Mediation by 5-hydroxytryptamine of morphine stimulant actions in dog intestine.

1973 • 111 citations

alpha 2-Adrenergic receptor regulation of ion transport in rabbit ileum

1982 • 108 citations

Serotonin receptor-mediated stimulation of bovine smooth muscle cell prostacyclin synthesis and its modulation by platelet-derived growth factor.

1981 • 106 citations

Regional localization of prostacyclin and thromboxane synthesis in dog stomach and intestinal tract.

1979 • 105 citations

Inhibition of stimulated fluid secretion in the rat small and large intestine by opiate agonists

1979 • 101 citations

Effect of serotonin treatment on intestinal transport in the rabbit.

1977 • 95 citations

Action of 5‐hydroxytryptamine on intestinal ion transport in the rat.

1981 • 93 citations

Bradykinin-stimulated electrolyte secretion in rabbit and guinea pig intestine. Involvement of arachidonic acid metabolites.

1983 • 93 citations

Effect of prostaglandin on ion transport across isolated colonic mucosa

1980 • 83 citations

Alpha-2 adrenergic inhibition of intestinal secretion induced by prostaglandin E1, vasoactive intestinal peptide and dibutyryl cyclic AMP in rat jejunum.

1982 • 81 citations

Enterocyte alpha 2-adrenergic receptors: yohimbine and p-aminoclonidine binding relative to ion transport

1983 • 79 citations

Opiate receptors as regulators of adenylate cyclase

1975 • 73 citations

Regulation of serotonin release from rabbit intestinal enterochromaffin cells.

1983 • 69 citations

Prostaglandin E₂ in jejunal fluids and its potential diagnostic value for selecting patients with indomethacin‐sensitive diarrhoea

1981 • 64 citations

Stimulation of adenylate cyclase in homogenates of isolated intestinal epithelial cells from hamsters

1978 • 62 citations

INHIBITION BY MORPHINE OF PROSTAGLANDIN E₁‐STIMULATED SECRETION AND CYCLIC ADENOSINE 3′,5′‐MONOPHOSPHATE FORMATION IN THE RAT JEJUNUM in vivo

1980 • 60 citations

PGE-release, blood flow and transmucosal water movement after mechanical stimulation of the rat jejunal mucosa

1978 • 55 citations

Stimulation of prostaglandin production in rabbit ileal mucosa by bradykinin.

1983 • 41 citations

Comparison of radioimmunological determinations with gas chromatography mass spectrometry dosage. A study of PGE2 and PGF2α in gastrointestinal fluids

1983 • 39 citations

Role of prostaglandins in the regulation of intestinal electrolyte transport

1981 • 36 citations

Vasodilator mechanisms in the small intestine. An experimental study in the cat.

1973 • 33 citations

THE RELEASE OF ACETYLCHOLINE FROM THE ISOLATED ILEUM OF THE GUINEA‐PIG INDUCED BY 5‐HYDROXYTRYPTAMINE AND DIMETHYLPHENYLPIPERAZINIUM

1965 • 32 citations

Serotonin participation in gut withdrawal from opiates.

1979 • 32 citations

Stimulation of adenylate cyclase in homogenates of isolated intestinal epithelial cells from hamsters

1978 • 27 citations

α2-Adrenoceptors modulating diarrhoea in morphine-dependent rats

1981 • 27 citations

VIP and PGE1 activate adenylate cyclase in rat intestinal epithelial cell membranes via different mechanisms

1981 • 17 citations

Prostaglandins and chronic diarrhoea: methodological problems.

1979 • 17 citations

Morphine Withdrawal in the Rat: Assessment by Quantitation of Diarrhea and Modification by Ethanol

1979 • 16 citations

Cyclic AMP and cyclic GMP in the rat gastric mucosa

1977 • 14 citations

Suppression of morphine withdrawal diarrhea by clonidine.

1981 • 12 citations

A long-acting silicone delivery system for morphine and naloxone administration

1978 • 10 citations

Naloxone reversal of drug-induced diarrhea in mice.

1979 • 4 citations

Rat strain differences in the opiate abstinence syndrome

1978 • 4 citations

The effect of narcotic agonists and antagonists on the rat colon.

1976 • 3 citations