Major Surgery Suppresses Maximal Production of Helper T-Cell Type 1 Cytokines Without Potentiating the Release of Helper T-Cell Type 2 Cytokines

Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells

1998 • 1,134 citations

Detection of intracellular cytokines by flow cytometry

1993 • 992 citations

Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo

1995 • 672 citations

Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases

1996 • 650 citations

Modulation of Epithelial Cell Growth by Intraepithelial γδ T Cells

1994 • 644 citations

Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations.

1995 • 554 citations

The influence of surgical operations on components of the human immune system

1985 • 407 citations

Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma

1996 • 390 citations

Distinct mechanisms of immunosuppression as a consequence of major surgery

1997 • 336 citations

Effects of anaesthesia and surgery on the immune response

1992 • 328 citations

IMMUNOSUPPRESSIVE EFFECT OF SURGERY

1971 • 314 citations

Chemokine expression by intraepithelial gamma delta T cells. Implications for the recruitment of inflammatory cells to damaged epithelia.

1996 • 250 citations

Altered helper and suppressor lymphocyte populations in surgical patients

1984 • 153 citations

The Delayed Hypersensitivity Response and Host Resistance in Surgical Patients

1995 • 141 citations

Expression of pro‐inflammatory cytokines by TCRαβ⁺ T and TCRγδ⁺ T cells in an experimental model of colitis

1997 • 121 citations

Lymphocyte Transformation and Changes in Leukocyte Count

1975 • 115 citations

Anaesthesia, surgery and immunology

1978 • 87 citations

Neuroendocrine and immunological mechanisms in stress-induced immunomodulation

1991 • 86 citations

Impaired production of interleukin-2 after surgery.

1985 • 74 citations

Depression of lymphocyte responses after surgical trauma.

1973 • 73 citations

Surgery, Trauma and Immune Suppression Evolving the Mechanism

1983 • 71 citations

Immune impairment and metastatic tumor growth.The need for an immunorestorative drug as an adjunct to surgery

1979 • 65 citations

Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases.

1996 • 50 citations

Detection of altered T helper 1 and T helper 2 cytokine production by peripheral blood mononuclear cells in patients with multiple sclerosis utilizing intracellular cytokine detection by flow cytometry and surface marker analysis

1996 • 41 citations

Post-operative depression of antibody-dependent lymphocyte cytotoxicity following minor surgery and anaesthesia.

1976 • 40 citations

Biology of murine gamma delta T cells.

1991 • 26 citations

Changes of White Blood Cells, Immunosuppressive Acidic Protein, and Interleukin-2 Receptor after Open Heart Surgery

1995 • 17 citations

Modulation of the cytokine and acute-phase response to major surgery by recombinant interleukin-2

1995 • 16 citations

Differential production of intracellular gamma interferon in alpha beta and gamma delta T-cell subpopulations in response to peritonitis

1995 • 15 citations

γδ T cells in bacterial infections

1996 • 14 citations

Changes in the productivity of cytokines and active-oxygen in peripheral blood cells following surgery

1992 • 11 citations

Kinetics of Splenocyte Interleukin-4 Production after Injury and Lethal Endotoxin Challenge

1997 • 6 citations

Modulation of the cytokine and acute-phase response to major surgery by recombinant interleukin 2

1995 • 3 citations