α7 Nicotinic acetylcholine receptor knockout selectively enhances ethanol-, but not β-amyloid-induced neurotoxicity

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

College Binge Drinking in the 1990s: A Continuing Problem Results of the Harvard School of Public Health 1999 College Alcohol Study

2000 • 1,043 citations

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease.

2001 • 516 citations

Mice Deficient in the α7 Neuronal Nicotinic Acetylcholine Receptor Lack α-Bungarotoxin Binding Sites and Hippocampal Fast Nicotinic Currents

1997 • 493 citations

Tobacco, alcohol, and caffeine use: A review of their interrelationships.

1984 • 479 citations

β-Amyloid Activates the Mitogen-Activated Protein Kinase Cascade via Hippocampal α7 Nicotinic Acetylcholine Receptors:In VitroandIn VivoMechanisms Related to Alzheimer's Disease

2001 • 446 citations

Amyloid Peptide Aβ_1‐42 Binds Selectively and with Picomolar Affinity to α7 Nicotinic Acetylcholine Receptors

2000 • 421 citations

β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons

2001 • 326 citations

Nicotinic receptor stimulation protects neurons against β‐amyloid toxicity

1997 • 320 citations

Characterization of nicotine binding in mouse brain and comparison with the binding of alpha-bungarotoxin and quinuclidinyl benzilate.

1982 • 305 citations

α7 Nicotinic Receptor Subunits Are Not Necessary for Hippocampal-Dependent Learning or Sensorimotor Gating: A Behavioral Characterization of Acra7-Deficient Mice

1998 • 295 citations

β-Amyloid Peptide Activates α7 Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes

2002 • 228 citations

Methyllycaconitine: a selective probe for neuronal α‐bungarotoxin binding sites

1990 • 220 citations

The α7 nicotinic acetylcholine receptor in neuronal plasticity

1999 • 207 citations

Characterization of a series of anabaseine-derived compounds reveals that the 3-(4)-dimethylaminocinnamylidine derivative is a selective agonist at neuronal nicotinic alpha 7/125I-alpha-bungarotoxin receptor subtypes.

1995 • 192 citations

Effects of ethanol on recombinant human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.

1999 • 187 citations

The α7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca2+ dependent mechanism

2000 • 183 citations

A new microcellular cytotoxicity test based on calcein AM release

1993 • 170 citations

Neuronal Degeneration in Rat Cerebrocortical and Olfactory Regions During Subchronic “Binge” Intoxication with Ethanol: Possible Explanation for Olfactory Deficits in Alcoholics

1996 • 168 citations

3-[2,4-Dimethoxybenzylidene]anabaseine (DMXB) selectively activates rat α7 receptors and improves memory-related behaviors in a mecamylamine-sensitive manner

1997 • 159 citations

Methyllycaconitine Is a Potent Antagonist of α-Conotoxin-MII-Sensitive Presynaptic Nicotinic Acetylcholine Receptors in Rat Striatum

2002 • 146 citations

Nicotinic α7 receptors protect against glutamate neurotoxicity and neuronal ischemic damage

1998 • 142 citations

Relationship between the increased cell surface α7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists

2001 • 120 citations

Ethanol inhibition of nicotinic acetylcholine type alpha 7 receptors involves the amino-terminal domain of the receptor.

1996 • 110 citations

Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries

2002 • 102 citations

The co-occurrence of smoking and binge drinking in adolescence

2000 • 88 citations

The correction of alpha7 nicotinic acetylcholine receptor concentration-response relationships in Xenopus oocytes

1998 • 85 citations

Absence of α7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures

2002 • 75 citations

Nicotinic Receptors Differentially RegulateN-Methyl-d-aspartate Damage in Acute Hippocampal Slices

2003 • 57 citations

Alpha7 nicotinic receptor activation inhibits ethanol‐induced mitochondrial dysfunction, cytochrome c release and neurotoxicity in primary rat hippocampal neuronal cultures

2002 • 46 citations

The α7 nicotinic acetylcholine receptor-selective antagonist, methyllycaconitine, partially protects against β-amyloid1–42 toxicity in primary neuron-enriched cultures

2004 • 38 citations

The Selectively Bred High Alcohol Sensitivity (HAS) and Low Alcohol Sensitivity (LAS) Rats Differ in Sensitivity to Nicotine

2002 • 33 citations

α7 Nicotinic acetylcholine receptor–mediated protection against ethanol-induced neurotoxicity

2003 • 15 citations