Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1992 • 2,905 citations

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1983 • 1,639 citations

ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism.

1996 • 1,004 citations

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

1994 • 994 citations

VIP21/caveolin is a cholesterol-binding protein.

1995 • 892 citations

Sterol Resistance in CHO Cells Traced to Point Mutation in SREBP Cleavage–Activating Protein

1996 • 473 citations

Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation.

1994 • 425 citations

Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts

1988 • 323 citations

Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid.

1996 • 257 citations

Selective inhibition of acyl coenzyme A:cholesterol acyltransferase by compound 58-035.

1984 • 230 citations

Regulated Cleavage of Sterol Regulatory Element Binding Proteins Requires Sequences on Both Sides of the Endoplasmic Reticulum Membrane

1996 • 198 citations

Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells.

1980 • 172 citations

Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells

1989 • 161 citations

Hairpin Orientation of Sterol Regulatory Element-binding Protein-2 in Cell Membranes as Determined by Protease Protection

1995 • 153 citations

Quantitation of the Pool of Cholesterol Associated with Acyl-CoA:Cholesterol Acyltransferase in Human Fibroblasts

1997 • 116 citations

Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase from the hamster. I. Isolation and sequencing of a full-length cDNA.

1986 • 109 citations

Three Different Rearrangements in a Single Intron Truncate Sterol Regulatory Element Binding Protein-2 and Produce Sterol-resistant Phenotype in Three Cell Lines

1995 • 96 citations

Plasma membrane sphingomyelin and the regulation of HMG-CoA reductase activity and cholesterol biosynthesis in cell cultures.

1991 • 92 citations

Sphingomyelin suppresses the binding and utilization of low density lipoproteins by skin fibroblasts.

1980 • 80 citations

Rapid turn-over of plasma membrane sphingomyelin and cholesterol in baby hamster kidney cells after exposure to sphingomyelinase

1990 • 63 citations

Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines

1996 • 61 citations

A 25-hydroxycholesterol-resistant cell line deficient in acyl-CoA: cholesterol acyltransferase

1991 • 36 citations

Modulation of sphingomyelinase-induced cholesterol esterification in fibroblasts, CaCo2 cells, macrophages and smooth muscle cells

1992 • 31 citations