The neuroprotection conferred by activating the mitochondrial ATP-sensitive K+ channel is mediated by inhibiting the mitochondrial permeability transition pore

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1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The Ca2+-induced membrane transition in mitochondria

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The Metabolism of Rat Brain Mitochondria

1970 • 560 citations

Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition

1998 • 381 citations

Mitochondrial ATP-Sensitive Potassium Channels Attenuate Matrix Ca ²⁺ Overload During Simulated Ischemia and Reperfusion

2001 • 362 citations

Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti‐apoptotic effects of melatonin

2004 • 302 citations

A Critical Reevaluation of the Intraluminal Thread Model of Focal Cerebral Ischemia

1998 • 287 citations

Mitochondrial intermembrane junctional complexes and their involvement in cell death

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Cyclosporin A protects against ischemia-reperfusion injury in the brain

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Preconditioning limits mitochondrial Ca²⁺during ischemia in rat hearts: role of K_ATPchannels

2001 • 168 citations

[Ca2+] Signaling between Mitochondria and Endoplasmic Reticulum in Neurons Is Regulated by Microtubules

2004 • 149 citations

Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition

2004 • 126 citations

Mitochondrial ATP-Sensitive Potassium Channel Activation Protects Cerebellar Granule Neurons From Apoptosis Induced by Oxidative Stress

2003 • 124 citations

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2002 • 120 citations

Roles of mitochondrial ATP-sensitive K channels and PKC in anti-infarct tolerance afforded by adenosine A1receptor activation

2000 • 117 citations

Cyclosporin A and its nonimmunosuppressive analogue N‐Me‐Val‐4‐cyclosporin A mitigate glucose/oxygen deprivation‐induced damage to rat cultured hippocampal neurons

1999 • 113 citations

Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins

1998 • 112 citations

Mitochondrial Potassium Channel Opener Diazoxide Preserves Neuronal-Vascular Function After Cerebral Ischemia in Newborn Pigs

1999 • 105 citations

Cyclosporin A Enhances Survival, Ameliorates Brain Damage, and Prevents Secondary Mitochondrial Dysfunction after a 30-Minute Period of Transient Cerebral Ischemia

2000 • 77 citations

Neuroprotection by cyclosporin A following transient brain ischemia correlates with the inhibition of the early efflux of cytochrome C to cytoplasm

2004 • 74 citations

Preservation of mitochondrial function by diazoxide during sustained ischaemia in the rat heart

2000 • 69 citations

Activation of mitochondrial ATP-sensitive potassium channels prevents neuronal cell death after ischemia in neonatal rats

2002 • 57 citations

Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels

2004 • 48 citations

Role of mitochondrial permeability transition in fetal brain damage in rats

2004 • 20 citations