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The Adrenal Functional Unit: A Hypothesis

Data up to Jan 2025

Published1980
Citations29
References70

Total Citations Per Year

Abstract

References (70)

Handbook of Physiology.

1960 • 10,428 citations

Tyrosine Hydroxylase

1964 • 2,038 citations

Advances in Enzymology

1963 • 606 citations

Control of Enzymatic Synthesis of Adrenaline in the Adrenal Medulla by Adrenal Cortical Steroids

1966 • 558 citations

THE THYROID. A FUNDAMENTAL AND CLINICAL TEXT

1956 • 474 citations

Frontiers in Catecholamine Research

1976 • 451 citations

The Enzymatic Conversion of 3,4-Dihydroxyphenylethylamine to Norepinephrine

1960 • 435 citations

Growth and Growth Hormone

1968 • 435 citations

Solubilization and Partial Purification of Tyrosine Hydroxylase from Bovine Adrenal Medulla

1971 • 412 citations

Steroids in Nonmammalian Vertebrates

1972 • 390 citations

Preparation and properties of a homogeneous aromatic l-amino acid decarboxylase from hog kidney

1970 • 346 citations

Serum Dopamine-Beta-Hydroxylase Activity

1971 • 327 citations

Adrenaline Synthesis: Control by the Pituitary Gland and Adrenal Glucocorticoids

1965 • 317 citations

Comparative Ability of Seminiferous Tubules and Interstitial Tissue of Rat Testes To Synthesize Androgens from Progesterone-4-14Cin Vitro

1965 • 309 citations

The natural history of the chromaffin cell

1965 • 285 citations

Functions of the adrenal cortex

1968 • 240 citations

A Requirement for Reduced Triphosphopyridine Nucleotide for Cholesterol Side-chain Cleavage by Mitochondrial Fractions of Bovine Adrenal Cortex

1961 • 194 citations

A TEXTBOOK OF COMPARATIVE ENDOCRINOLOGY

1962 • 194 citations

Dopamine- -hydroxylase: regulation of its synthesis and release from nerve terminals.

1972 • 167 citations

A Kinetic Study of Bovine Adrenal Tyrosine Hydroxylase

1966 • 167 citations

Effects of Amino-glutethimide on Adrenal Function in Man1

1967 • 154 citations

Control of Epinephrine Synthesis in the Adrenal Medulla by the Adrenal Cortex: Hormonal Specificity and Dose-Response Characteristics

1966 • 137 citations

Adrenocortical control of the biosynthesis of epinephrine and proteins in the adrenal medulla.

1972 • 137 citations

An assay for dopamine-β-hydroxylase activity in tissues and serum

1971 • 126 citations

Tissue fractionation and catecholamines—II

1968 • 117 citations

On the Identification of Octopamine in Mammals

1962 • 114 citations

Mechanism of Inhibition of Adrenal Steroid 11β-Hydroxylase by Methopyrapone (Metopirone)

1963 • 101 citations

Effect of Pituitary and ACTH on the Maintenance of Basal Tyrosine Hydroxylase Activity in the Rat Adrenal Gland

1970 • 86 citations

Mechanism of ACTH action

1972 • 79 citations

Stimulation of Adrenal Cholesterol Uptake from Plasma by Adrenocorticotrophin

1970 • 78 citations

The human adrenal gland

1961 • 78 citations

On the mechanism of action of thyroxin, an amino acid analog of tyrosine

1974 • 78 citations

The Human Testis

1970 • 77 citations

ADRENALINE FORMATION IN NORADRENALINE-STORING CHROMAFFIN CELLS IN VITRO INDUCED BY CORTICOSTERONE

1966 • 76 citations

Enzymatic Formation of Adrenaline and Other Catechols from Monophenols

1963 • 72 citations

Increased tyrosine hydroxylase activity of sympathetic ganglia cultured in the presence of dibutyryl cyclic AMP

1972 • 70 citations

Dopamine-β-hydroxylase Activity in the Rat After Hypophysectomy

1970 • 65 citations

Dual Sites of Inhibition by Metyrapone of Human Adrenal Steroidogenesis: Correlation ofin Vivoand andin VitroStudies

1976 • 63 citations

Species Differences in Inducibility of Phenylethanolamine-N-Methyl Transferase

1968 • 61 citations

Studies on the Biosynthetic Conversion of Cholesterol into Pregnenolone

1972 • 59 citations

Effect of Hypophysectomy on Immobilization-Induced Elevation of Tyrosine Hydroxylase and Phenylethanolamine-N-methyl Transferase in the Rat Adrenal

1970 • 56 citations

Konjugation micronucleusloser Paramaecien

1939 • 55 citations

Biosynthesis of adrenaline and noradrenaline.

1959 • 54 citations

Hydroxylation of steroids by microorganisms in the presence of 18O2

1956 • 53 citations

Biosynthesis of Pregnenolone

1971 • 46 citations

Vitamin C in the suprarenal medulla

1933 • 45 citations

THE ROLE OF CYTOCHROME P‐450 AND P‐448 IN DRUG AND STEROID HYDROXYLATIONS

1973 • 41 citations

An Effect of Adrenocorticotrophic Hormone on Adrenal Cholesterol Accumulation

1967 • 40 citations

Inhibition of Enzymatic Synthesis of Epinephrine by Low Doses of Glucocorticoids

1967 • 33 citations

Substrate-induced Difference Spectral, Electron Paramagnetic Resonance, and Enzymatic Properties of Cholesterol-depleted Mitochondrial Cytochrome P-450 of Bovine Adrenal Cortex

1973 • 33 citations

NADH(NADPH):(Acceptor) oxidoreductase activities of the bovine adrenal chromaffin granules

1973 • 32 citations

Effects of Metyrapone on Pregnenolone Biosynthesis and on Cholesterol-Cytochrome P-450 Interaction in the Adrenal1

1974 • 31 citations

A Study of the Mechanisms by Which Adrenocorticotropic Hormone Maintains Adrenal Steroidogenic Responsiveness*

1967 • 28 citations

Subcellular distribution of adrenal tyrosine hydroxylase

1968 • 28 citations

The adrenal cortex

1967 • 25 citations

Steroid Induction of Phenylethanolamine-N-methyl Transferase in Adrenomedullary Explants: Independence of Adrenal Innervation

1970 • 22 citations

The free and esterified sterol present in bovine adrenal cortex and medulla

1964 • 20 citations

Induction of Epinephrine-forming Enzyme by Glucocorticoids: Steroid Hydroxylation and Inductive Effect

1968 • 17 citations

SITES OF METYRAPONE INHIBITION OF STEROID BIOSYNTHESIS BY RAT ADRENAL MITOCHONDRIA

1974 • 17 citations

Effects of aminoglutethimide, metyrapone, and ascorbic acid on testicular metabolism of cholesterol

1974 • 15 citations

FAILURE TO ISOLATE CORTISOL FROM A PHEOCHROMOCYTOMA*

1960 • 13 citations

Steroid biosynthesis by painted turtle (Chrysemys picta picta) adrenals

1972 • 12 citations

Steroid 11β-Oxygenation, Ascorbic Acid, Epinephrine and Adrenochrome Interrelations in the Adrenal Gland

1965 • 12 citations

METABOLISM OF [4-14C]CHOLESTEROL BY HUMAN ADRENAL GLANDS IN VITRO AND ITS INHIBITION BY METYRAPONE

1974 • 11 citations

Effect of Hydrocortisone on Histochemically Demonstrable Catecholamines of the Para‐aortic Body of the Rat

1966 • 10 citations

Effects of Corynebacterium parvum on Immunological Unresponsiveness to Bovine Serum Albumin in the Rabbit

1967 • 10 citations

Effect of ACTH and Dibutyryl Cyclic AMP on Catecholamine Synthesizing Enzymes in the Adrenals of Hypophysectomized Rats

1971 • 8 citations

Studies on cytochrome b561 in amine storage granules

1975 • 7 citations

Effect of Cortisone on Extra-adrenal Chromaffin Tissue of the Rat

1963 • 7 citations

Control of adrenal medullary protein synthesis by corticosteroids

1973 • 2 citations

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