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Mechanism of ACTH action

Data up to Jan 2025

Published1972
Citations79
References97

Total Citations Per Year

Abstract

References (97)

An Adenosine 3′,5′-Monophosphate-dependant Protein Kinase from Rabbit Skeletal Muscle

1968 • 1,423 citations

Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)

1968 • 976 citations

Hypophysectomy and a replacement therapy in the rat

1930 • 552 citations

Morphological Transformation of Chinese Hamster Cells by Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate and Testosterone

1971 • 529 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 469 citations

Studies on ACTH action in perfused bovine adrenals: The site of action of ACTH in corticosteroidogenesis

1954 • 446 citations

Restoration of Several Morphological Characteristics of Normal Fibroblasts in Sarcoma Cells Treated with Adenosine-3′:5′-Cyclic Monophosphate and Its Derivatives

1971 • 440 citations

Inactivation of Glycogen Synthetase and Activation of Phosphorylase Kinase by Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases

1970 • 410 citations

Histone Phosphorylation: Stimulation by Adenosine 3′,5′-Monophosphate

1968 • 402 citations

Adenosine 3‘,5‘-Monophosphate as the Intracellular Mediator of the Action of Adrenocorticotropic Hormone on the Adrenal Cortex

1967 • 395 citations

Studies on the role of protein synthesis in the regulation of corticosterone production by adrenocorticotropic hormone in vivo.

1965 • 389 citations

A cyclic-3′,5′-adenosine monophosphate dependent protein kinase from the adrenal cortex: Comparison with a cyclic AMP binding protein

1970 • 382 citations

Protein Synthesis and Adrenocorticotropin Responsiveness

1963 • 345 citations

Influence of Adenosine 3′, 5 ′ -monophosphate on Corticoid Production by Rat Adrenal Glands

1959 • 323 citations

Restoration of Contact-Inhibited Growth to Transformed Cells by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

1971 • 321 citations

The Activation of Adrenal Phosphorylase by the Adrenocorticotropic Hormone

1958 • 316 citations

STUDIES ON THE MECHANISM OF ACTION OF THE ADRENOCORTICOTROPIC HORMONE

1957 • 311 citations

ACTH Receptors in the Adrenal: Specific Binding of ACTH- 125 I and Its Relation to Adenyl Cyclase

1970 • 303 citations

HORMONE-PRODUCING CULTURES OF ADRENAL AND PITUITARY TUMOR ORIGIN

1962 • 285 citations

Mechanism of Activation by Adenosine 3′:5′-Cyclic Monophosphate of a Protein Phosphokinase from Rabbit Reticulocytes

1970 • 283 citations

Separation of regulatory and catalytic subunits of the cyclic 3′, 5′-adenosine monophosphate-dependent protein kinase(s) of rabbit skeletal muscle

1971 • 253 citations

On the Mechanism of Action of ACTH

1971 • 250 citations

Identity of the Site of Action of 3',5'-Adenosine Monophosphate and Adrenocortocotropic Hormone in Corticosteroidogenesis in Rat Adrenal and Beef Adrenal Cortex Slices*

1965 • 248 citations

Lac DNA, RNA Polymerase and Cyclic AMP Receptor Protein, Cyclic AMP, Lac Repressor and Inducer are the Essential Elements for Controlled Lac Transcription

1971 • 238 citations

Mode of action of adenosine 3′,5′-cyclic phosphate on protein kinase from rat liver

1970 • 224 citations

Purification of and Properties of the Cyclic Adenosine 3',5'-Monophosphate Receptor Protein which Mediates Cyclic Adenosine 3',5'-Monophosphate-dependent Gene Transcription in Escherichia coli

1971 • 210 citations

Cyclic Adenosine 3′:5′-Monophosphate-Stimulated Phosphorylation of Isolated Neurotubule Subunits

1970 • 206 citations

Adrenal Cholesterol: Localization by Electron-Microscope Autoradiography

1969 • 206 citations

Action of Adenosine 3',5'-Monophosphate-dependent Histone Kinase in Vivo

1969 • 203 citations

Phosphorylation of ribosomal proteins in rabbit reticulocytes. Characterization and regulatory aspects

1970 • 196 citations

A Requirement for Reduced Triphosphopyridine Nucleotide for Cholesterol Side-chain Cleavage by Mitochondrial Fractions of Bovine Adrenal Cortex

1961 • 194 citations

Effects of Calcium on ACTH Stimulation of the Adrenal: Separation of Hormone Binding from Adenyl Cyclase Activation

1970 • 166 citations

On the Mechanism of Action of the Adrenocorticotrophic Hormone

1970 • 158 citations

Role of the Receptor in the Mechanism of Action of Adenosine 3′:5′-Cyclic Monophosphate

1971 • 149 citations

Adrenal cells in tissue culture

1968 • 144 citations

The Synthesis of Acidic Nuclear Proteins in the Prereplicative Phase of the Isoproterenol-stimulated Salivary Gland

1970 • 135 citations

Phosphorylation of some rat liver ribosomal proteins and its activation by cyclic AMP

1970 • 135 citations

Inhibition of Replication in Functional Mouse Adrenal Tumor Cells by Adrenocorticotropic Hormone Mediated by Adenosine 3′:5′-Cyclic Monophosphate

1971 • 134 citations

Interaction of the Subunits of Adenosine 3′:5′-Cyclic Monophosphate-Dependent Protein Kinase of Muscle

1971 • 130 citations

Cleavage of Cholesterol Side Chain by Adrenal Cortex

1961 • 130 citations

On the Mechanism of Action of Adrenocorticotropic Hormone

1968 • 129 citations

Restoration of glucagon responsiveness of solubilized myocardial adenyl cyclase by phosphatidylserine

1971 • 123 citations

The cholesterol side-chain cleavage system of the adrenal cortex: A mixed-function oxidase

1966 • 123 citations

Protamine Kinase from Rainbow Trout Testis

1970 • 121 citations

ATP-Dependent and Cyclic AMP-Dependent Activation of Rat Adipose Tissue Lipase by Protein Kinase from Rabbit Skeletal Muscle

1970 • 121 citations

ROLE OF CHROMATIN IN ESTROGEN ACTION IN THE UTERUS, II. HORMONE-INDUCED SYNTHESIS OF NONHISTONE ACIDIC PROTEINS WHICH RESTORE HISTONE-INHIBITED DNA-DEPENDENT RNA SYNTHESIS

1969 • 117 citations

Evidence for a Noncatalytic Carrier Protein in Cholesterol Biosynthesis

1971 • 116 citations

Abnormal hormone responses of an adrenocortical cancer adenyl cyclase

1971 • 116 citations

Interconversion of Cyclic Nucleotide-Activated and Cyclic Nucleotide-Independent Forms of a Protein Kinase from Beef Heart

1971 • 115 citations

Phosphorylation of rat liver ribosomal subunits: Partial purification of two cyclic AMP activated protein kinases

1971 • 111 citations

Purification and DNA-Binding Properties of the Catabolite Gene Activator Protein

1971 • 109 citations

Phosphorylation of Ribosome-Associated Protein by an Adenosine 3′:5′-Cyclic Monophosphate-Dependent Protein Kinase: Location of the Microsomal Receptor and Protein Kinase

1971 • 98 citations

End-Product Inhibition of the Conversion of Cholesterol to Pregnenolone in an Adrenal Extract*

1964 • 94 citations

Site of action of adrenocorticotropic hormone (ACTH) in adrenal cell cultures

1968 • 93 citations

Effect of protein kinase on ribonucleic acid polymerase

1970 • 90 citations

Effect of acth on cholesterol side-chain cleavage in rat adrenal mitochondria

1972 • 87 citations

On the Mechanism of Action of Adrenocorticotropic Hormone

1970 • 87 citations

Correlation of Adrenocorticotropic Activity of ACTH Analogs with Degree of Binding to an Adrenal Cortical Particulate Preparation

1970 • 86 citations

Multiple Specific Hormone Receptors in the Adenylate Cyclase of an Adrenocortical Carcinoma

1971 • 86 citations

GLUCOSE-6-PHOSPHATE DEHYDROGENASE OF ADRENAL TISSUE

1955 • 79 citations

Site of Action of Trophic Hormones Upon the Biosynthetic Pathways to Steroid Hormones

1968 • 79 citations

Stimulation of Adrenal Cholesterol Uptake from Plasma by Adrenocorticotrophin

1970 • 78 citations

The Regulatory Role of Adenosine-3',5'-Phosphate

1961 • 76 citations

Actinomycin-insensitive Stimulation of Protein Synthesis in Rat Anterior Pituitary in Vitro by Dibutyryl Adenosine 3', 5'-Monophosphate

1971 • 72 citations

ON THE MECHANISM OF ACTION OF ADRENOCORTICOTROPIC HORMONE: THE BINDING OF CYCLIC-3′,5′-ADENOSINE MONOPHOSPHATE TO AN ADRENAL CORTICAL PROTEIN

1969 • 72 citations

Evidence for the stimulation by adrenocorticotropic hormone of the conversion of cholesterol esters to cholesterol in the adrenal, in, vivo

1966 • 71 citations

Production of Steroids byin VitroSuperfusion of Endocrine Tissue. III. Corticosterone Output from Rat Adrenals Stimulated by Adrenocorticotropin or Cyclic 3′,5′-Adenosine Monophosphate and the Inhibitory Effect of Cycloheximide

1970 • 69 citations

Interaction with Phosphodiesterase of Free and Kinasecomplexed Cyclic Adenosine 3',5'-Monophosphate

1971 • 68 citations

The Mechanism of Action of Adrenocorticotropic Hormone

1969 • 67 citations

On the Mechanism of Action of Adrenocorticotropic Hormone

1971 • 66 citations

Observations on the interrelations between adrenal protein, RNA and DNA during prolonged ACTH administration

1963 • 66 citations

Inhibition of Adrenal Protein Synthesis by Steroidsin Vitro1

1967 • 65 citations

Adrenocorticotrophin-Induced Changes in the Steroidogenic Activity of Adrenal Cell-Free Preparations*

1967 • 63 citations

THE ACTION OF CORTICOTROPIN (ACTH) ON NUCLEIC ACIDS AND SUBCELLULAR ELEMENTS OF THE ADRENAL CORTEX

1956 • 53 citations

Calcium as a Mediator of Adrenocorticotrophic Hormone Action on Adrenal Protein Synthesis

1971 • 49 citations

Biosynthesis of Pregnenolone

1971 • 46 citations

Acth stimulation of adenyl cyclase in adrenal homogenates

1967 • 43 citations

Heterogeneity of Template RNA in Adrenal Glands

1966 • 37 citations

A possible mechanism for the transfer of cytosol-generated NADPH to the mitochondrial mixed-function oxidases in bovine adrenal cortex: A malate shuttle

1968 • 35 citations

Effect of Adrenocorticotrophin on Adrenal Protein Synthesis1

1963 • 35 citations

Synthesis of ribonucleic acids in the adrenal cortex: Eatly effects of adrenocorticotropic hormone

1964 • 34 citations

Spin state changes in cytochrome P‐450 associated with cholesterol side chain cleavage in bovine adrenal cortex mitochondria

1971 • 33 citations

Translation-Level Control of Amylase and Protein Synthesis by Epinephrine

1970 • 33 citations

On the mechanism of action of adrenocorticotropic hormone. The stimulation of thymidine kinase activity with altered properties and changed subcellular distribution.

1971 • 32 citations

Effects of Dibutyryl Cyclic AMP on Adrenal Growth and Steroidogenic Capacity

1969 • 32 citations

Adenosine 3′,5′-Monophosphate, Adrenocorticotropic Hormone, and Adrenocortical Cytosol Protein Synthesis

1970 • 32 citations

Formation of Isocaproaldehyde in the Enzymatic Cleavage of Cholesterol Side Chain by Adrenal Extract*

1966 • 30 citations

Stimulation of Pregnenolone Synthesis by ACTH in Rat Adrenal Sections

1971 • 28 citations

A Study of the Mechanisms by Which Adrenocorticotropic Hormone Maintains Adrenal Steroidogenic Responsiveness*

1967 • 28 citations

Effect of Hypophysectomy on NADP and NADPH Concentration and Corticosteroid Secretion in the Rat Adrenal

1964 • 23 citations

Phenotypic Alterations in Adrenal Tumor Cultures

1965 • 22 citations

Effects of ACTH on Adrenal RNA Synthesis1

1967 • 22 citations

Stimulation of steroid transformations in adrenal mitochondria by cyclic 3′,5′-adenosine phosphate

1965 • 20 citations

Adrenocorticotrophin and Adrenal Protein Synthesis1

1965 • 20 citations

Adrenal Cells in Tissue Culture. VII. Effect of Inhibitors of Protein Synthesis on Steroidogenesis and Glycolysis1

1970 • 13 citations

Changes in Adrenal Polysomes Following ACTH Administration1

1965 • 12 citations

Quantitative Comparison of the Effects of ACTH Administration on the Activities of Soluble Cell Fraction and Microsomes for Incorporation of Amino Acid Into Protein

1965 • 10 citations

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Mechanism of ACTH action (1972) – Metabolism | Metascience Observatory Explorer