Evidence that Intestinal Glucagon-Like Peptide-1 Plays a Physiological Role in Satiety

Biology of Incretins: GLP-1 and GIP

2007 • 3,315 citations

A role for glucagon-like peptide-1 in the central regulation of feeding

1996 • 1,880 citations

Cholecystokinin decreases food intake in rats.

1973 • 1,454 citations

Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system

1999 • 733 citations

Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem

1997 • 608 citations

The inhibitory effects of peripheral administration of peptide YY3–36 and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal–brainstem–hypothalamic pathway

2005 • 578 citations

A Recombinant Human Glucagon-Like Peptide (GLP)-1–Albumin Protein (Albugon) Mimics Peptidergic Activation of GLP-1 Receptor–Dependent Pathways Coupled With Satiety, Gastrointestinal Motility, and Glucose Homeostasis

2004 • 371 citations

Peripheral Oxyntomodulin Reduces Food Intake and Body Weight Gain in Rats

2004 • 338 citations

Gastrointestinal satiety signals II. Cholecystokinin

2004 • 326 citations

Gastrointestinal Satiety Signals

2007 • 323 citations

Glucagon-Like Peptide-1 (GLP-1) Receptors Expressed on Nerve Terminals in the Portal Vein Mediate the Effects of Endogenous GLP-1 on Glucose Tolerance in Rats

2007 • 308 citations

Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage

2005 • 306 citations

Peripheral Exendin-4 and Peptide YY3–36 Synergistically Reduce Food Intake through Different Mechanisms in Mice

2005 • 302 citations

Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells

2004 • 268 citations

Vagal afferent and efferent contributions to the inhibition of food intake by cholecystokinin

1997 • 221 citations

Leptin Regulation of the Anorexic Response to Glucagon-Like Peptide-1 Receptor Stimulation

2006 • 177 citations

Tissue distribution of rat glucagon receptor and GLP-1 receptor gene expression1This work was supported by a grant from the Crohn's and Colitis Foundation of America.1

1998 • 159 citations

Peripheral versus central effects of glucagon-like peptide-1 receptor agonists on satiety and body weight loss in Zucker obese rats

2000 • 158 citations

Antiobesity action of peripheral exenatide (exendin-4) in rodents: effects on food intake, body weight, metabolic status and side-effect measures

2006 • 135 citations

Signals that influence food intake and body weight

2005 • 135 citations

Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats

2005 • 127 citations

Oxyntomodulin Differentially Affects Glucagon-Like Peptide-1 Receptor β-Arrestin Recruitment and Signaling through Gα

2007 • 125 citations

The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size

2007 • 109 citations

CCK-receptor antagonists attenuate suppression of sham feeding by intestinal nutrients

1992 • 92 citations

Stable expression of the rat GLP-I receptor in CHO cells: Activation and binding characteristics utilizing GLP-I(7–36)-amide, oxyntomodulin, exendin-4, and exendin(9–39)

1994 • 85 citations

Oxyntomodulin increases intrinsic heart rate in mice independent of the glucagon-like peptide-1 receptor

2006 • 54 citations

Cholecystokinin conditions flavor preferences in rats

1991 • 40 citations

Type A CCK receptors mediate satiety effects of intestinal nutrients

1996 • 37 citations

Effects of peripheral CCK receptor blockade on food intake in rats

2003 • 34 citations

Introduction to the reviews on peptides and the control of food intake and body weight

1999 • 33 citations

The caudal brainstem is sufficient to mediate inhibition of gastric emptying by peripheral glucagon-like-peptide-1 receptor activation.

2007 • 1 citations