Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: mapping of mutations conferring resistance

Manual of Clinical Microbiology

1970 • 2,775 citations

Antibiotics in Laboratory Medicine.

1980 • 2,763 citations

Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis

1993 • 1,307 citations

Interaction of antibiotics with functional sites in 16S ribosomal RNA

1987 • 1,143 citations

An Outbreak of Multidrug-Resistant Tuberculosis among Hospitalized Patients with the Acquired Immunodeficiency Syndrome

1992 • 909 citations

Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support

1989 • 747 citations

Comparative Anatomy of 16-S-like Ribosomal RNA

1985 • 689 citations

Collection of small subunit (16S- and 16S-like) ribosomal RNA structures: 1994

1994 • 533 citations

Inhibitors of protein synthesis

1974 • 411 citations

Molecular basis of streptomycin resistance in Mycobacterium tuberculosis: alterations of the ribosomal protein S12 gene and point mutations within a functional 16S ribosomal RNA pseudoknot

1993 • 354 citations

Mechanisms of antibiotic resistance in bacteria.

1987 • 340 citations

Differentiation of Mycobacterium species by direct sequencing of amplified DNA

1990 • 305 citations

The Molecular Basis of Antibiotic Action

1973 • 298 citations

A functional pseudoknot in 16S ribosomal RNA.

1991 • 287 citations

Conservation of primary structure in 16S ribosomal RNA

1975 • 231 citations

Whither short-course chemotherapy?

1981 • 214 citations

Ribosomal proteins

1972 • 211 citations

Antibiotic resistance mutations in the chloroplast 16S and 23S rRNA genes of Chlamydomonas reinhardtii: correlation of genetic and physical maps of the chloroplast genome.

1989 • 177 citations

STREPTOMYCIN RESISTANCE: A GENETICALLY RECESSIVE MUTATION

1951 • 176 citations

Collection of small subunit (16S- and 16S-like) ribosomal RNA structures

1993 • 171 citations

Altered ribosomal RNA genes in mitochondria from mammalian cells with chloramphenicol resistance

1981 • 154 citations

Insertional mutagenesis and illegitimate recombination in mycobacteria.

1991 • 153 citations

MOLECULAR BIOLOGY OF THE MYCOBACTERIA

1989 • 145 citations

DRUG RESISTANCE IN MYCOBACTERIA

1984 • 134 citations

GENETIC ANALYSIS OF STREPTOMYCIN RESISTANCE IN ESCHERICHIA COLI

1970 • 122 citations

Identification of two erythromycin resistance mutations in the mitochondrial gene coding for the large ribosomal RNA in yeast

1982 • 118 citations

Streptomycin and Misreading of the Genetic Code

1974 • 117 citations

E. coli ribosomes with a C912 to U base change in the 16S rRNA are streptomycin resistant.

1986 • 104 citations

Streptomycin preferentially perturbs ribosomal proofreading

1984 • 103 citations

A mutation in the 530 loop ofEscherichia coli16S ribosomal RNA causes resistance to streptomycin

1988 • 94 citations

The nucleotide sequence of the promoter, 16S rRNA and spacer region of the ribosomal RNA operon of Mycobacterium tuberculosis and comparison with Mycobacterium leprae prefnsor rRNA

1992 • 93 citations

Streptomycin-resistance ofEuglena gracilischloroplasts: identification of a point mutation in the 16S rRNA gene in an invariant position

1985 • 86 citations

Erythromycin and spiramycin resistance mutations of yeast mitochondria: nature of therib2locus in the large ribosomal RNA gene

1984 • 80 citations

Different nucleotide changes in the large rRNA gene of the mitochondrial DNA confer chloramphenicol resistance on two human cell lines

1981 • 79 citations

Organization of rRNA genes in Mycobacterium bovis BCG

1987 • 76 citations

Inhibitors of Protein Synthesis

1977 • 70 citations

Mapping of chloroplast mutations conferring resistance to antibiotics in Chlamydomonas: Evidence for a novel site of streptomycin resistance in the small subunit rRNA

1988 • 62 citations

A point mutation in the chloroplast 16 S rRNA gene of a streptomycin resistant Nicotiana tabacum

1987 • 58 citations

Diagnostic Molecular Microbiology

2018 • 57 citations

A novel site for streptomycin resistance in the ?530 loop? of chloroplast 16S ribosomal RNA

1989 • 55 citations

The new tuberculosis.

1994 • 49 citations

Point mutations in the 23 S rRNA genes of four lincomycin resistant Nicotiana plumbaginifolia mutants could provide new selectable markers for chloroplast transformation

1988 • 49 citations

Sequence analysis of mitochondrial DNA in a mouse cell line resistant to chloramphenicol and oligomycin.

1983 • 44 citations

Resistance to macrolides, lincosamides and streptogramin type B antibiotics due to a mutation in an rRNA operon of Streptomyces ambofaciens.

1988 • 38 citations

The 5' proximal helix of 16S rRNA is involved in the binding of streptomycin to the ribosome.

1993 • 34 citations

Protein Synthesis in Mycobacterium tuberculosis H37Rv and the Effect of Streptomycin in Streptomycin-Susceptible and -Resistant Strains

1973 • 30 citations

THE DOMINANCE OF STREPTOMYCIN SENSITIVITY RE-EXAMINED

1969 • 16 citations

Analysis of streptomycin-resistance of Escherichia coli mutants

1991 • 16 citations