Defining the regulatory networks for muscle development

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

1995 • 1,278 citations

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

1995 • 1,154 citations

p53-Independent Expression of p21 ^Cip1 in Muscle and Other Terminally Differentiating Cells

1995 • 1,058 citations

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

1995 • 817 citations

Wnt-3a regulates somite and tailbud formation in the mouse embryo.

1994 • 784 citations

Early stages of chick somite development

1995 • 781 citations

Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis.

1996 • 601 citations

Patterning of mammalian somites by surface ectoderm and notochord: Evidence for sclerotome induction by a hedgehog homolog

1994 • 594 citations

Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite.

1995 • 504 citations

Requirement of MADS Domain Transcription Factor D-MEF2 for Muscle Formation in Drosophila

1995 • 502 citations

Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites

1994 • 451 citations

Drosophila MEF2, a transcription factor that is essential for myogenesis.

1995 • 426 citations

MyoD-Induced Expression of p21 Inhibits Cyclin-Dependent Kinase Activity upon Myocyte Terminal Differentiation

1995 • 416 citations

Lateral and Axial Signals Involved in Avian Somite Patterning: A Role for BMP4

1996 • 416 citations

Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase

1995 • 404 citations

Regulation of Muscle Differentiation by the MEF2 Family of MADS Box Transcription Factors

1995 • 348 citations

Inactivation of the myogenic bHLH gene MRF4 results in up-regulation of myogenin and rib anomalies.

1995 • 308 citations

Myogenin is required for late but not early aspects of myogenesis during mouse development.

1995 • 292 citations

Transcription factor families: muscling in on the myogenic program.

1995 • 261 citations

D-MEF2: a MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis.

1994 • 225 citations

Activation of the Myogenic Lineage by MEF2A, a Factor that Induces and Cooperates with MyoD

1994 • 223 citations

Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome

1995 • 220 citations

Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse

1996 • 215 citations

Wingless Signaling InducesnautilusExpression in the Ventral Mesoderm of theDrosophilaEmbryo

1996 • 214 citations

Activation of different myogenic pathways: myf-5 is induced by the neural tube and MyoD by the dorsal ectoderm in mouse paraxial mesoderm

1996 • 212 citations

A Series of Mutations in the D-MEF2 Transcription Factor Reveal Multiple Functions in Larval and Adult Myogenesis in Drosophila

1995 • 209 citations

Mutational Analysis of the DNA Binding, Dimerization, and Transcriptional Activation Domains of MEF2C

1996 • 203 citations

Combinatorial signals from the neural tube, floor plate and notochord induce myogenic bHLH gene expression in the somite

1995 • 194 citations

Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators.

1994 • 186 citations

Embryonic activation of the myoD gene is regulated by a highly conserved distal control element

1995 • 173 citations

Inactivation of Myf-6 and Myf-5 genes in mice leads to alterations in skeletal muscle development.

1995 • 172 citations

D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis.

1994 • 171 citations

Myogenesis in paraxial mesoderm: preferential induction by dorsal neural tube and by cells expressing Wnt-1

1995 • 171 citations

Functional redundancy of the muscle-specific transcription factors Myf5 and myogenin

1996 • 157 citations

Myogenin and MEF2 Function Synergistically To Activate the MRF4 Promoter during Myogenesis

1995 • 151 citations

Control of somite patterning by signals from the lateral plate.

1995 • 141 citations

Expression of the positive regulator of cell cycle progression, cyclin D3, is induced during differentiation of myoblasts into quiescent myotubes.

1995 • 141 citations

Positive and Negative Regulation of D-type Cyclin Expression in Skeletal Myoblasts by Basic Fibroblast Growth Factor and Transforming Growth Factor β

1995 • 133 citations

A Single MEF2 Site Governs Desmin Transcription in Both Heart and Skeletal Muscle during Mouse Embryogenesis

1996 • 130 citations

Myogenic specification in somites: induction by axial structures

1994 • 118 citations

Drosophila MEF2 is regulated by twist and is expressed in both the primordia and differentiated cells of the embryonic somatic, visceral and heart musculature

1995 • 113 citations

The Regulation of MyoD Gene Expression: Conserved Elements Mediate Expression in Embryonic Axial Muscle

1995 • 110 citations

Myf-5 and myoD genes are activated in distinct mesenchymal stem cells and determine different skeletal muscle cell lineages.

1996 • 102 citations

Isolated sequences from the linked Myf-5 and MRF4 genes drive distinct patterns of muscle-specific expression in transgenic mice

1993 • 102 citations

Neural Tube and Notochord Promote in Vitro Myogenesis in Single Somite Explants

1995 • 101 citations

Physical Interaction between the Mitogen-responsive Serum Response Factor and Myogenic Basic-Helix-Loop-Helix Proteins

1996 • 100 citations

DNA Binding Specificity Determinants in MADS-Box Transcription Factors

1995 • 98 citations

The Mouse MRF4 Promoter Is trans-Activated Directly and Indirectly by Muscle-specific Transcription Factors

1995 • 93 citations

Multiple Changes in E2F Function and Regulation Occur upon Muscle Differentiation

1995 • 91 citations

Expression of the D-MEF2 transcription in the Drosophila brain suggests a role in neuronal cell differentiation.

1996 • 90 citations

Alterations in somite patterning of Myf-5-deficient mice: a possible role for FGF-4 and FGF-6

1996 • 85 citations

Characterization of transcription factor E2F complexes during muscle and neuronal differentiation.

1995 • 82 citations

Expression and activity of the retinoblastoma protein (pRB)-family proteins, p107 and p130, during L6 myoblast differentiation.

1995 • 79 citations

Coordinate positioning of MEF2 and myogenin binding sites

1996 • 74 citations

The dorsal neural tube organizes the dermamyotome and induces axial myocytes in the avian embryo

1996 • 73 citations

Myogenic Specification of Somites Is Mediated by Diffusible Factors

1995 • 64 citations

Lineage restriction of the myogenic conversion factor myf-5 in the brain

1995 • 57 citations

Quail MyoD Is Regulated by a Complex Array of cis-Acting Control Sequences

1995 • 21 citations