Cloning the interleukin 1 receptor from human T cells.

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 • 896 citations

Interleukin 1, a potential regulator of fibroblast proliferation.

1982 • 835 citations

Interleukin-1 Mitogenic Activity for Fibroblasts and Smooth Muscle Cells Is Due to PDGF-AA

1989 • 648 citations

Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1).

1981 • 614 citations

Protein Import into the Cell Nucleus

1986 • 544 citations

The cell surface receptors for interleukin-1α and interleukin-1β are identical

1986 • 422 citations

Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism

1988 • 413 citations

Detection and characterization of high affinity plasma membrane receptors for human interleukin 1.

1985 • 397 citations

Interleukin 1 alpha and interleukin 1 beta bind to the same receptor on T cells.

1986 • 286 citations

Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation.

1988 • 247 citations

Properties of a specific interleukin 1 (IL 1) receptor on human Epstein Barr virus-transformed B lymphocytes: identity of the receptor for IL 1-alpha and IL 1-beta.

1986 • 225 citations

Identification of a common class of high affinity receptors for both types of porcine interleukin-1 on connective tissue cells

1986 • 219 citations

Binding and internalization of interleukin 1 by T cells. Direct evidence for high- and low-affinity classes of interleukin 1 receptor.

1986 • 194 citations

The interleukin 1 receptor. Dynamics of interleukin 1 binding and internalization in T cells and fibroblasts.

1987 • 190 citations

Transmembrane signaling during interleukin 1-dependent T cell activation. Interactions of signal 1- and signal 2-type mediators with the phosphoinositide-dependent signal transduction mechanism.

1987 • 157 citations

Binding, internalization, and intracellular localization of interleukin-1 beta in human diploid fibroblasts.

1988 • 156 citations

Similarity between the interleukin 1 receptors on a murine T-lymphoma cell line and on a murine fibroblast cell line.

1986 • 144 citations

Interleukin‐1 regulation of hematopoietic growth factor production by human stromal fibroblasts

1988 • 136 citations

Identification of a high-affinity receptor for native human interleukin 1 beta and interleukin 1 alpha on normal human lung fibroblasts.

1987 • 132 citations

Interleukin-1 generates transmembrane signals from phospholipids through novel pathways in cultured rat mesangial cells.

1989 • 128 citations

A biochemical and kinetic analysis of the interleukin-1 receptor. Evidence for differences in molecular properties of IL-1 receptors.

1987 • 123 citations

Interleukin 1: more than a mediator between leukocytes

1988 • 120 citations

IL-1 and TNF transmodulate epidermal growth factor receptors by a protein kinase C-independent mechanism.

1989 • 116 citations

Retention of ligand binding activity by the extracellular domain of the IL-1 receptor.

1989 • 111 citations

T-cell interleukin 1 receptor cDNA expressed in Chinese hamster ovary cells regulates functional responses to interleukin 1.

1989 • 97 citations

Interleukin 1 and tumour necrosis factor increase phosphorylation of fibroblast proteins

1988 • 86 citations

Affinity purification and chemical analysis of the interleukin-1 receptor.

1988 • 86 citations

Purification and characterization of a cytosolic 65-kilodalton phosphoprotein in human leukocytes whose phosphorylation is augmented by stimulation with interleukin 1

1988 • 73 citations

Murine interleukin‐1 receptor: Differences in binding properties between fibroblastic and thymoma cells and evidence for a two‐chain receptor model

1987 • 56 citations

Murine interleukin 1 receptor. Direct identification by ligand blotting and purification to homogeneity of an interleukin 1-binding glycoprotein.

1988 • 48 citations

Interleukin 1 and the glomerular mesangium. III. IL-1-dependent stimulation of mesangial cell protein kinase activity

1988 • 40 citations

IL 1 expression in a clone of human T cells.

1987 • 38 citations

Identification of the plasma membrane receptor for interleukin‐1 on mouse thymoma cells

1987 • 33 citations

Interleukin 1 Induces Specific Phosphorylation of a 41 kDa Plasma Membrane Protein from the Human Tumor Cell Line K 562

1986 • 15 citations