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Influence of allelic polymorphism on the assembly and surface expression of class II MHC (Ia) molecules

Data up to Jan 2025

Published1985
Citations119
References44

Total Citations Per Year

Abstract

References (44)

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

Properties of Monoclonal Antibodies to Mouse Ig Allotypes, H-2, and Ia Antigens

1979 • 993 citations

The class II molecules of the human and murine major histocompatibility complex

1984 • 664 citations

A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication.

1981 • 531 citations

A BIOLOGICAL ROLE FOR THE MAJOR HISTOCOMPATIBILITY ANTIGENS

1975 • 488 citations

Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity.

1982 • 481 citations

A molecular map of the immune response region from the major histocompatibility complex of the mouse

1982 • 466 citations

Genes of the Major Histocompatibility Complex of the Mouse

1983 • 445 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

The Immune Response Genes of the Major Histocompatibility Complex

1978 • 382 citations

Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules.

1983 • 312 citations

Interleukin-induced increase in Ia expression by normal mouse B cells.

1984 • 293 citations

Quantitative variation in la antigen expression plays a central role in immune regulation

1984 • 270 citations

Immune Response(Ir)Genes of the Murine Major Histocompatibility Complex

1986 • 217 citations

Regions of allelic hypervariability in the murine Aα immune response gene

1983 • 185 citations

Structure of the murine immune response I-Aβ locus: Sequence of the I-Aβ gene and an adjacent β-chain second domain exon

1983 • 184 citations

The murine Eα immune response gene

1983 • 180 citations

Expression of H-2Dd and H-2Ld mouse major histocompatibility antigen genes in L cells after DNA-mediated gene transfer.

1983 • 144 citations

Murine I-Aβ Chain Polymorphism: Nucleotide Sequences of Three Allelic I-Aβ Genes

1983 • 139 citations

Polymorphism of the Mouse H‐2 Loci

1981 • 136 citations

The nucleotide sequence of the murine I-E beta b immune response gene: evidence for gene conversion events in class II genes of the major histocompatibility complex.

1984 • 131 citations

Immune response gene function correlates with the expression of an Ia antigen. II. A quantitative deficiency in A(e):E(a), complex expression causes a corresponding defect in antigen-presenting cell function

1982 • 115 citations

"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta.

1985 • 98 citations

Membrane Ia expression and antigen-presenting accessory cell function of L cells transfected with class II major histocompatibility complex genes.

1984 • 95 citations

Immune response gene function correlates with the expression of an Ia antigen. I. Preferential association of certain Ae and E alpha chains results in a quantitative deficiency in expression of an Ae:E alpha complex.

1982 • 87 citations

Studies Utilizing Murine T Cell Clones Ir Genes, Ia Antigens and MLR Stimulating Determinants

1981 • 87 citations

DNA Sequence of the Gene Encoding the EαIa Polypeptide of the BALB/c Mouse

1982 • 85 citations

Isolation and characterization of a cDNA clone for the murine I-E beta polypeptide chain.

1983 • 81 citations

Establishment of B cell hybridomas with B cell surface antigens.

1982 • 80 citations

The Eb beta gene may have acted as the donor gene in a gene conversion-like event generating the Abm 12 beta mutant.

1984 • 62 citations

Small subunit of I–A subregion antigens determines the allospecificity recognized by a monoclonal antibody

1980 • 60 citations

Functional expression of a transfected murine class II MHC gene

1983 • 59 citations

Molecular characterization of the recombination region of six murine major histocompatibility complex (MHC) I-region recombinants.

1984 • 59 citations

Expression of I–Ak class II genes in mouse L cells after DNA-mediated gene transfer

1983 • 58 citations

Interaction between I region loci influences the expression of a cell surface Ia antigen.

1980 • 55 citations

MAJOR HISTOCOMPATIBILITY ANTIGENS

1981 • 52 citations

Extensive polymorphism surrounding the murine Ia A beta chain gene.

1983 • 52 citations

T cell clones specific for hybrid I-A molecules. Discrimination with monoclonal anti-I-A (k) antibodies

1982 • 48 citations

HLA and Diseases: Involvement of More than One HLA‐Linked Determinant of Disease Susceptibility

1983 • 46 citations

Comparison of MHC genes among distantly related members of the genus Mus.

1985 • 35 citations

Differential expression of Ia glycoprotein complexes in F1 hybrid mice detected with alloreactive cloned T cell lines.

1982 • 34 citations

The beta 1 domain of the mouse E beta chain is important for restricted antigen presentation to helper T-cell hybridomas.

1985 • 29 citations

Cell surface expression of an in vitro recombinant class II/class I major histocompatibility complex gene product

1985 • 23 citations

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