Nimodipine Pretreatment Improves Cerebral Blood Flow and Reduces Brain Edema in Conscious Rats Subjected to Focal Cerebral Ischemia

Thresholds in cerebral ischemia - the ischemic penumbra.

1981 • 2,780 citations

Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

1987 • 1,821 citations

The Importance of Beta, the Type II Error and Sample Size in the Design and Interpretation of the Randomized Control Trial

1978 • 1,634 citations

Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis

1989 • 1,237 citations

Cerebral Arterial Spasm – A Controlled Trial of Nimodipine in Patients with Subarachnoid Hemorrhage

1983 • 1,148 citations

Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial.

1989 • 1,087 citations

Moderate hyperglycemia augments ischemic brain damage

1982 • 730 citations

Nimodipine treatment in poor-grade aneurysm patients

1988 • 527 citations

Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries

1988 • 488 citations

A Controlled Trial of Nimodipine in Acute Ischemic Stroke

1988 • 423 citations

The Quantification of Cerebral Infarction following Focal Ischemia in the Rat: Influence of Strain, Arterial Pressure, Blood Glucose Concentration, and Age

1988 • 393 citations

Principles of the design and operation of generic osmotic pumps for the delivery of semisolid or liquid drug formulations

1976 • 365 citations

Experimental brain infarcts in cats. II. Ischemic brain edema.

1980 • 363 citations

The importance of brain temperature in cerebral ischemic injury.

1989 • 318 citations

Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia.

1987 • 302 citations

Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat. I. Local cerebral blood flow and glucose utilization.

1980 • 294 citations

Prevention of vasospasm in subarachnoid haemorrhage. A controlled study with nimodipine

1986 • 282 citations

Stroke: Pathophysiology, Diagnosis, and Management

1986 • 262 citations

Pharmacological basis for the use of nimodipine in central nervous system disorders

1989 • 248 citations

Cerebral microcirculation and metabolism

1982 • 227 citations

The effects of a calcium antagonist, nimodipine, upon physiological responses of the cerebral vasculature and its possible influence upon focal cerebral ischaemia.

1982 • 195 citations

Effect of nimodipine on the outcome of patients after aneurysmal subarachnoid hemorrhage and surgery

1988 • 181 citations

Hyperglycemia Increases Infarct Size in Collaterally Perfused but Not End-Arterial Vascular Territories

1988 • 178 citations

Effect of pretreatment with the calcium antagonist nimodipine on local cerebral blood flow and histopathology after middle cerebral artery occlusion

1985 • 173 citations

Extracellular pH, Potassium, and Calcium Activities in Progressive Ischaemia of Rat Cortex

1984 • 168 citations

Focal cerebral ischemia in the rat: Topography of hemodynamic and histopathological changes

1984 • 157 citations

Middle cerebral artery occlusion in the young rat.

1982 • 150 citations

THE MICROVASCULATURE AND MICROCIRCULATION OF THE CEREBRAL CORTEX AFTER ARTERIAL OCCLUSION

1967 • 147 citations

Nimodipine and the Haemodynamic and Histopathological Consequences of Middle Cerebral Artery Occlusion in the Rat

1986 • 147 citations

Brain blood flow in the conscious and anesthetized rat

1973 • 143 citations

Regional brain blood flow in the conscious gerbil.

1978 • 134 citations

Differential outcome to middle cerebral artery occlusion in spontaneously hypertensive stroke-prone rats (SHRSP) and Wistar Kyoto (WKY) rats.

1983 • 128 citations

Selective Gene Expression in Focal Cerebral Ischemia

1986 • 123 citations

Different susceptibilities to cerebral infarction in spontaneously hypertensive (SHR) and normotensive Sprague-Dawley rats.

1986 • 120 citations

Nimodipine attenuates both increase in cytosolic free calcium and histologic damage following focal cerebral ischemia and reperfusion in cats.

1989 • 120 citations

Effect of nimodipine on intracellular brain pH, cortical blood flow, and EEG in experimental focal cerebral ischemia

1986 • 113 citations

Selective Central Nervous System Calcium Channel Blockers—a New Class of Anticonvulsant Agents

1986 • 108 citations

Pharmacology of Nimodipine

1988 • 106 citations

Continuous Nimodipine Treatment Attenuates Cortical Infarction in Rats Subjected to 24 Hours of Focal Cerebral Ischemia

1990 • 97 citations

Effect of the NMDA Antagonist MK-801 on Local Cerebral Blood Flow in Focal Cerebral Ischaemia in the Rat

1989 • 93 citations

Effect of the Calcium Antagonist Nimodipine on Local Cerebral Blood Flow: Relationship to Arterial Blood Pressure

1984 • 85 citations

An Evaluation of Errors in the Determination of Blood Flow by the Indicator Fractionation and Tissue Equilibration (Kety) Methods

1984 • 78 citations

Rate-Controlled Delivery Systems in Drug and Hormone Research

1984 • 72 citations

Inhibition of electrically induced seizures by a dihydropyridine calcium channel blocker

1986 • 71 citations

Cerebral Acidosis in Focal Ischemia: II. Nimodipine and Verapamil Normalize Cerebral pH following Middle Cerebral Artery Occlusion in the Rat

1986 • 71 citations

Acute Thrombotic Infarction Suppresses Metabolic Activation of Ipsilateral Somatosensory Cortex: Evidence for Functional Diaschisis

1989 • 65 citations

Effects of Cerebral Ischemia in Various Strains of Rats.

1965 • 62 citations

Cerebral infarction after middle cerebral artery occlusion in progenies of spontaneously stroke-prone and normal rats.

1984 • 62 citations

"Low perfusion hyperemia" following middle cerebral arterial occlusion in cats of different age groups.

1980 • 58 citations

Comparison of radio-labeled butanol and iodoantipyrine as cerebral blood flow markers

1981 • 52 citations

Calcium channel blockers correct acidosis in ischemic rat brain without altering cerebral blood flow.

1988 • 40 citations

Focal Cerebral Infarction

1988 • 31 citations

Are the Vascular Effects of Naloxone Attributable to the Preservatives Methyl- and Propylparaben?

1983 • 30 citations

Effects of nimodipine on cerebral blood flow in conscious rat.

1986 • 29 citations

Nimodipine Prevents Hyperglycemia-Induced Cerebral Acidosis in Middle Cerebral Artery Occluded Rats

1989 • 28 citations

Nifedipine and Nimodipine: Effect on Blood Pressure and Regional Cerebral Blood Flow in Conscious Normotensive and Hypertensive Rats

1985 • 24 citations

THE ADDITION OF NITROUS OXIDE TO HALOTHANE DECREASES RENAL AND SPLANCHNIC FLOW AND INCREASES CEREBRAL BLOOD FLOW IN RATS

1986 • 23 citations

Cellular Calcium Metabolism, Seizures, and Ischemia

1986 • 21 citations

Bimodal treatment with nimodipine and low‐molecular‐weight dextran for focal cerebral ischemia in the rat

1989 • 19 citations

Ischemic Vasoconstriction and Parenchymal Brain pH

1988 • 13 citations

Nimodipine

1985 • 9 citations