Patch clamp and atomic force microscopy demonstrate TATA-binding protein (TBP) interactions with the nuclear pore complex

Atomic Force Microscope

1986 • 14,074 citations

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

From Molecules to Cells: Imaging Soft Samples with the Atomic Force Microscope

1992 • 886 citations

O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation

1988 • 884 citations

TBP, a universal eukaryotic transcription factor?

1993 • 642 citations

A protein-conducting channel in the endoplasmic reticulum

1991 • 613 citations

Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy.

1992 • 611 citations

Functional Domains and Upstream Activation Properties of Cloned Human TATA Binding Protein

1990 • 471 citations

Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.

1987 • 428 citations

Glycosylation of nuclear and cytoplasmic proteins. Purification and characterization of a uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase.

1992 • 420 citations

Transcription by RNA polymerase II: initiator‐directed formation of transcription‐competent complexes ¹

1992 • 412 citations

The basics of basal transcription by RNA polymerase II

1994 • 409 citations

Biological applications of atomic force microscopy

1994 • 399 citations

GLYCOSYLATION IN THE NUCLEUS AND CYTOPLASM

1989 • 380 citations

Counting polymers moving through a single ion channel

1994 • 368 citations

General Initiation Factors for RNA Polymerase II

1993 • 346 citations

Commitment and activation at pol II promoters: A tail of protein-protein interactions

1990 • 332 citations

Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway.

1987 • 330 citations

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box

1989 • 303 citations

Special Issue: Dynamics of Molecular Systems

1990 • 255 citations

Atomic Force Microscopy and Dissection of Gap Junctions

1991 • 241 citations

Growth Factors Proto-Oncogenes and Plasticity of the Cardiac Phenotype

1991 • 228 citations

Signal peptides open protein-conducting channels in E. coli

1992 • 216 citations

Drug-metabolizing enzymes in ligand-modulated transcription

1994 • 207 citations

1.9 Å resolution refined structure of TBP recognizing the minor groove of TATAAAAG

1994 • 206 citations

Biological Applications of Scanning Probe Microscopes

1991 • 202 citations

Atomic force microscopy for high-resolution imaging in cell biology

1992 • 202 citations

Putative nuclear localization signals (NLS) in protein transcription factors

1994 • 199 citations

Architectural Transcription Factors

1994 • 187 citations

Glycosylation of nuclear and cytoplasmic proteins is ubiquitous and dynamic

1992 • 183 citations

The TATA-Binding Protein: a General Transcription Factor in Eukaryotes and Archaebacteria

1994 • 183 citations

Structure of the extracellular surface of the gap junction by atomic force microscopy

1993 • 170 citations

Molecular cloning of Drosophila TFIID subunits

1994 • 114 citations

Increased Recruitment of TATA-Binding Protein to the Promoter by Transcriptional Activation Domains in Vivo

1994 • 114 citations

Transcription factor (TF) IIB and TFIIA can independently increase the affinity of the TATA-binding protein for DNA.

1994 • 112 citations

2.1 Å resolution refined structure of a TATA box-binding protein (TBP)

1994 • 102 citations

Nuclear pore complex: structure, function, and regulation.

1991 • 97 citations

Phenotype suppression: A postulated molecular mechanism for mediating the relationship of proliferation and differentiation by Fos/Jun interactions at AP‐1 sites in steroid responsive promoter elements of tissue‐specific genes

1991 • 89 citations

The role of activators in assembly of RNA polymerase II transcription complexes

1994 • 86 citations

Imaging nuclear pores of aldosterone-sensitive kidney cells by atomic force microscopy.

1994 • 78 citations

The ion channel behavior of the nuclear pore complex

1995 • 74 citations

Biological applications of scanning probe microscopies

1994 • 73 citations

Duality of TBP, the Universal Transcription Factor

1994 • 71 citations

Multichannel recordings from membranes which contain gap junctions

1992 • 66 citations

Towards understanding the three-dimensional structure of the nuclear pore complex at the molecular level

1994 • 65 citations

Imaging the lamellipodium of migrating epithelial cells in vivo by atomic force microscopy

1993 • 46 citations

Multimerization of the mouse TATA-binding protein (TBP) driven by its C-terminal conserved domain

1994 • 44 citations

Nuclear ion channels in cardiac myocytes

1992 • 43 citations

Atomic force microscopy of cloned nicotinic acetylcholine receptor expressed in Xenopus oocytes.

1993 • 38 citations

Multichannel recordings from membranes which contain gap junctions. II. Substates and conductance shifts

1993 • 38 citations

Structure and activation dynamics of RBL-2H3 cells observed with scanning force microscopy

1994 • 36 citations

Nuclear electrophysiology

1994 • 34 citations

Imaging of reconstituted biological channels at molecular resolution by atomic force microscopy

1993 • 33 citations

Patch clamp detection of transcription factor translocation along the nuclear pore complex channel

1995 • 32 citations

Nuclear pore complex ion channels (Review)

1994 • 31 citations

Restricted ion flow at the nuclear envelope of cardiac myocytes

1993 • 30 citations

Coactivators and TAFs: A New Class of Eukaryotic Transcription Factors That Connect Activators to the Basal Machinery

1993 • 25 citations

Transcription factors: A new frontier in pharmaceutical development?

1994 • 14 citations

Nucleotide Sequence of a Fragment of HeLa-cell Mitochondrial DNA Containing the Precisely Localized Origin of Replication

1979 • 13 citations

Open states of nuclear envelope ion channels in cardiac myocytes

1994 • 12 citations

Highly sensitive control of transcriptional activity by factor heterodimerization

1994 • 10 citations

Polymer tubules prepared

1993 • 8 citations

Mechanism of DNA-drug interactions

1994 • 7 citations