Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Nucleotide sequence of the rightward operator of phage lambda.

1975 • 2,068 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

NUCLEOSIDE-PHOSPHORYLASE DEFICIENCY IN A CHILD WITH SEVERELY DEFECTIVE T-CELL IMMUNITY AND NORMAL B-CELL IMMUNITY

1975 • 855 citations

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

1977 • 416 citations

Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum

1984 • 263 citations

Biochemistry of Diseases of Immunodevelopment

1981 • 242 citations

Site-specific polyadenylation in a cell-free reaction

1984 • 223 citations

Abnormal Purine Metabolism and Purine Overproduction in a Patient Deficient in Purine Nucleoside Phosphorylase

1976 • 175 citations

Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: Genetic model for immunodeficiency disease

1979 • 158 citations

A possible nucleotide-binding domain in the tertiary fold of phosphoribosyltransferases.

1983 • 137 citations

Purine Nucleoside Phosphorylase from Human Erythrocytes

1969 • 101 citations

Purification and characterization of human erythrocyte purine nucleoside phosphorylase and its subunits.

1978 • 87 citations

Cloning of human purine-nucleoside phosphorylase cDNA sequences by complementation in Escherichia coli.

1983 • 74 citations

A patient with nucleoside phosphorylase deficiency, selective T-cell deficiency, and autoimmune hemolytic anemia

1978 • 49 citations

A new form of nucleoside phosphorylase deficiency in two brothers with defective T-cell function

1978 • 48 citations

An abnormal form of purine nucleoside phosphorylase in a family with a child with severe defective T-cell-and normal B-cell immunity

1976 • 37 citations

Selective severe cellular immunodeficiency

1976 • 32 citations

Characterization of mutant subunits of human purine nucleoside phosphorylase.

1978 • 31 citations

Crystallization and preliminary X-ray investigation of human erythrocytic purine nucleoside phosphorylase.

1981 • 23 citations

Submolecular characterization of a mutant human purine-nucleoside phosphorylase.

1980 • 10 citations