Studies on the mechanism of uncoupling by amine local anesthetics. Evidence for mitochondrial proton transport mediated by lipophilic ion pairs.

Partition coefficients and their uses

1971 • 4,444 citations

[73] Spectrophotometric and turbidimetric methods for measuring proteins

1957 • 3,309 citations

The membrane actions of anesthetics and tranquilizers.

1972 • 2,194 citations

Regulation of Metabolic Processes in Mitochondria

1967 • 1,182 citations

The interaction of highly active uncouplers with mitochondria

1981 • 302 citations

Reaction of Local Anesthetics with Phospholipids

1964 • 259 citations

Chloride‐Hydroxide Exchange across Mitochondrial, Erythrocyte and Artificial Lipid Membranes Mediated by Trialkyl‐ and Triphenyltin Compounds

1970 • 249 citations

β-Adrenoceptor Antagonists: New Drugs and New Indications

1981 • 231 citations

Some observations on the photometric estimation of mitochondrial volume

1958 • 175 citations

Inhibition and activation of calcium transport in mitochondria. Effect of lanthanides and local anesthetic drugs

1969 • 170 citations

On the mechanism of regulation of the mitochondrial K+/H+ exchanger.

1980 • 160 citations

Cation binding to submitochondrial particles

1968 • 143 citations

The displacement of membrane calcium by a local anesthetic (chlorpromazine)

1969 • 140 citations

The effect of local anesthetics on the hydrolysis of free and membrane-bound phospholipids catalyzed by various phospholipases

1972 • 112 citations

Quinine inhibition of Na+ and K+ transport provides evidence for two cation/H+ exchangers in rat liver mitochondria.

1982 • 103 citations

The control of Ca2+ release from heart mitochondria.

1981 • 95 citations

Multiple sites of inhibition of mitochondrial electron transport by local anesthetics

1981 • 91 citations

On the mechanism of A23187-induced potassium efflux in rat liver mitochondria.

1980 • 84 citations

Oil-Water Partitioning of Chlorpromazine and Other Phenothiazine Derivatives Using Dodecane and n-Octanol

1970 • 78 citations

Mechanism of uncoupling in mitochondria: uncouplers as ionophores for cycling cations and protons.

1976 • 77 citations

Ion pair extraction of pharmaceutical amines. Role of dipolar solvating agents in extraction of dextromethorphan

1967 • 69 citations

Effect of Catecholamines and Adrenergic Blocking Agents on Oxidative Phosphorylation in Rat Heart Mitochondria

1966 • 66 citations

Enhancement of Gastrointestinal Absorption of a Quaternary Ammonium Compound by Trichloroacetate

1969 • 60 citations

Inhibition of Ca2+ efflux from mitochondria by nupercaine and tetracaine

1979 • 50 citations

Lipid-protein interactions in mitochondria

1975 • 42 citations

On the mechanism of action of anesthetics. Direct inhibition of mitochondrial F1-ATPase by N-butanol and tetracaine

1981 • 42 citations

Uncouplers and the molecular mechanism of uncoupling in mitochondria.

1977 • 42 citations

Inhibition of K+ transport in liver mitochondria

1967 • 39 citations

EFFECT OF PROGESTERONE ON OXIDATIVE PHOSPHORYLATION

1956 • 38 citations

Mechanism of 3,5-di-tert-butyl-4-hydroxybenzylidenemalononitrile-mediated proton uptake in liposomes. Kinetics of proton uptake compensated by valinomycin-induced k+-efflux

1978 • 37 citations

Lidocaine Effects on Brain Mitochondrial Metabolism in Vitro

1975 • 32 citations

Some effects of local anesthetics on isolated mitochondria.

1969 • 30 citations

Action of propranolol on mitochondrial functions—effects on energized ion fluxes in the presence of valinomycin

1975 • 28 citations

Action of local anaesthetics on passive and energy-linked ion translocation in the inner mitochondrial membrane

1972 • 27 citations

Complex formation between the uncoupler carbonyl cyanide p-trifluoromethoxyphenylhydrazone (FCCP) and valinomycin in the presence of potassium.

1978 • 26 citations

Chlordimeform: Uncoupling activity against rat liver mitochondria

1973 • 26 citations

The action of Nupercaine on calcium efflux from rat liver mitochondria

1980 • 26 citations

Energy-Dependent contraction of swollen heart mitochondria—Activation by butacaine

1979 • 24 citations

Effects of quinidine and propranolol on energy transduction in beef heart mitochondria

1979 • 19 citations

Inhibition of mitochondrial anion permeability by local anaesthetics

1978 • 17 citations

The effects of miconazole on rat liver mitochondria

1977 • 16 citations

Effective enhancement of valinomycin-mediated potassium uptake in organic phase by uncouplers of oxidative phosphorylation detected by proton NMR

1981 • 15 citations

Inhibition by local anaesthetics of anion transport in isolated rat heart mitochondria

1979 • 14 citations

The effect of ketamine hydrochloride, a non-barbiturate parenteral anaesthetic on oxidative phosphorylation in rat liver mitochondria

1981 • 12 citations

The interaction of organic cations with the mitochondrial membrane

1976 • 11 citations

The effect of butacaine on adenine nucleotide binding and translocation in rat liver mitochondria

1975 • 11 citations

Local anesthetic activity of 2-piperazinecarboxanilides

1972 • 10 citations

The determination of partition coefficient data using the “AKUFVE” method

1974 • 10 citations

Inhibition of mitochondrial swelling by 19-nor-ethynyltestosterone acetate and other steroids

1971 • 10 citations

Action of propranolol on mitochondrial functions—effects on non-energized ion fluxes

1975 • 8 citations

Progesterone stimulates energy-dependent contraction of swollen heart mitochondria

1981 • 7 citations