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Defective interleukin-2 induction of lymphokine-activatedkiller (LAK) activity in peripheral blood T lymphocytesof patients with monoclonal gammopathies

Data up to Jan 2025

Published1990
Citations25
References30

Total Citations Per Year

Abstract

References (30)

Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens.

1983 • 852 citations

Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.

1986 • 698 citations

Novel Interleukin-2 Receptor Subunit Detected by Cross-Linking Under High-Affinity Conditions

1986 • 585 citations

Natural Cytotoxic Reactivity of Human Lymphocytes Against a Myeloid Cell Line: Characterization of Effector Cells

1977 • 493 citations

Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.

1986 • 477 citations

Lymphokine-activated killer cells. Analysis of progenitors and effectors.

1986 • 403 citations

Effects of natural and recombinant IL 2 on regulation of IFN gamma production and natural killer activity: lack of involvement of the Tac antigen for these immunoregulatory effects.

1984 • 310 citations

Characterization of a phenotypically distinct subpopulation of Leu-2+ cells that suppresses T cell proliferative responses.

1983 • 251 citations

Morphologic and phenotypic features of the subpopulation of Leu-2+ cells that suppresses B cell differentiation.

1984 • 196 citations

Interleukin 2-activated human killer cells are derived from phenotypically heterogeneous precursors.

1986 • 166 citations

Alloantigen-specific cytotoxic and suppressor T lymphocytes are derived from phenotypically distinct precursors.

1983 • 151 citations

Characterization of human lymphocyte subpopulations: Alloreactive cytotoxic T-lymphocyte precursor and effector cells are phenotypically distinct from Leu 2+ suppressor cells

1984 • 112 citations

Unmaintained remissions in multiple myeloma

1978 • 96 citations

Low plasma cell 3(H) thymidine incorporation in monoclonal gammopathy of undetermined significance (MGUS), smouldering myeloma and remission phase myeloma: a reliable indicator of patients not requiring therapy

1984 • 93 citations

Activated idiotype-reactive cells in suppressor/cytotoxic subpopulations of monoclonal gammopathies: correlation with diagnosis and disease status

1988 • 66 citations

The human myeloma cell line LP-1: a versatile model in which to study early plasma-cell differentiation and c-myc activation

1989 • 59 citations

Strong natural killer (NK) cell activity in bone marrow of myeloma patients: Accelerated maturation of bone marrow NK cells and their interaction with other bone marrow cells

1984 • 57 citations

CD11 molecule defines two types of suppressor cells within the T8+ population

1988 • 50 citations

Activated idiotype-reactive cells in suppressor/cytotoxic subpopulations of monoclonal gammopathies: correlation with diagnosis and disease status

1988 • 49 citations

Recombinant interferon alfa-2b (INTRON A) as post-induction therapy for responding multiple myeloma patients. M84 protocol

1988 • 45 citations

CD8+CD11b+ peripheral blood T lymphocytes contain lymphokine‐activated killer cell precursors

1989 • 43 citations

Defective generation of alloreactive cytotoxic T lymphocytes (CTL) in human monoclonal gammopathies.

1988 • 41 citations

Major histocompatibility complex-unrestricted cytolytic activity of human T cells. Analysis of precursor frequency and effector phenotype.

1987 • 40 citations

Differential expression of ecto-5' nucleotidase activity by functionally and phenotypically distinct subpopulations of human Leu-2+/T8+ lymphocytes.

1986 • 28 citations

The generation of alloreactive cytotoxic T lymphocytes requires the expression of ecto-5'nucleotidase activity.

1988 • 24 citations

Surface markers and cytotoxic activities of lymphocytes in monoclonal gammopathy of undetermined significance and untreated multiple myeloma

1987 • 21 citations

Multiple myeloma: ecto-5' nucleotidase deficiency of suppressor/cytotoxic (CD8) lymphocytes is a marker for the expansion of suppressor T cells.

1987 • 17 citations

Emergence of activated lymphocytes in CD4 and CD8 subpopulations of multiple myeloma: correlation with the expansion of suppressor T-cells (CD8+ OKM1+) and ecto-5'nucleotidase deficiency.

1988 • 11 citations

Long Unmaintained Remission in Multiple Myeloma

1986 • 7 citations

Biochemical evidence for the presence of abnormal B lymphocytes in the peripheral blood of multiple myeloma patients.

1987 • 1 citations

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Defective interleukin-2 induction of lymphokine-activatedkiller (LAK) activity in… (1990) – Clinical & Experimental Immunology | Metascience Observatory Explorer