Effect of anti-interferon-γ and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse

Biostatistical Analysis.

1975 • 10,200 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

EXACERBATIONS OF MULTIPLE SCLEROSIS IN PATIENTS TREATED WITH GAMMA INTERFERON

1987 • 1,062 citations

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Large Scale Preparation of Myelin Basic Protein from Central Nervous Tissue of Several Mammalian Species

1972 • 949 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

1988 • 731 citations

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis.

1990 • 692 citations

Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes.

1981 • 592 citations

Effect of interleukin 2, interferon-gamma, and mitogens on the production of tumor necrosis factors alpha and beta.

1985 • 492 citations

Thymoma production of T cell growth factor (Interleukin 2).

1980 • 487 citations

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma.

1988 • 432 citations

Biology of disease. Analysis of autoimmune demyelination: its impact upon multiple sclerosis.

1984 • 424 citations

Protective effect of transforming growth factor beta 1 on experimental autoimmune diseases in mice.

1991 • 400 citations

Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1.

1991 • 385 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

Interferon-gamma induces enhanced expression of Ia and H-2 antigens on B lymphoid, macrophage, and myeloid cell lines.

1983 • 228 citations

Unsuspected Multiple Sclerosis

1983 • 217 citations

Interferons as macrophage-activating factors. III. Preferential effects of interferon-gamma on the interleukin 1 secretory potential of fresh or aged human monocytes.

1985 • 217 citations

Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats

1990 • 207 citations

Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice.

1985 • 194 citations

Inhibition of B lymphocyte activation by interferon-gamma.

1987 • 164 citations

Hyperinducibility of Ia antigen on astrocytes correlates with strain-specific susceptibility to experimental autoimmune encephalomyelitis.

1987 • 163 citations

Anti-interleukin 2 receptor antibody suppresses murine diabetic insulitis and lupus nephritis.

1988 • 141 citations

The role of interferon‐gamma in the pathogenesis of experimental autoimmune disease of the peripheral nervous system

1990 • 120 citations

Interaction between myelin basic protein-sensitized T lymphocytes and murine cerebral vascular endothelial cells.

1986 • 117 citations

Orally inducible immune unresponsiveness is abrogated by IFN-gamma treatment.

1990 • 113 citations

Heterogeneous effects of IFN-gamma in adjuvant arthritis.

1989 • 109 citations

Regulation of murine in vivo lgG and lgE responses by a monoclonal anti-IL-4 receptor antibody

1991 • 79 citations

γ‐Interferon‐Induced Activation of Latent Transforming Growth Factor‐β by Human Monocytes

1990 • 73 citations

Suppression of Experimental Allergic Encephalomyelitis by Interferon

1982 • 71 citations

Production of BSF-1 during an in vivo, T-dependent immune response.

1986 • 51 citations

Anti-interleukin 2 receptor antibody suppresses delayed-type hypersensitivity to foreign and syngeneic antigens.

1986 • 39 citations

In vivotreatment of rats with monoclonal antibodies against gamma interferon: effects on experimental allergic neuritis

1989 • 37 citations

Molecular and cellular determinants of neuroimmunologic inflammatory disease.

1982 • 30 citations

Expression of 20-alpha-hydroxysteroid dehydrogenase in mouse macrophages, hemopoietic cells, and cell lines and its induction by colony-stimulating factors.

1985 • 26 citations

Chronic relapsing necrotizing encephalomyelitis produced by myelin basic protein in mice.

1987 • 18 citations

Suppression of chronic-relapsing experimental allergic encephalomyelitis in strain-13 guinea pigs by administration of liposome-associated myelin basic protein

1984 • 13 citations