Guidance of circumferentially growing axons by the floor plate in the vertebrate central nervous system

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

1996 • 1,253 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor

1996 • 982 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene

1997 • 764 citations

Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons

1988 • 739 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

Mutations affecting growth cone guidance in drosophila: Genes necessary for guidance toward or away from the midline

1993 • 677 citations

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1995 • 566 citations

Organization of hindbrain segments in the zebrafish embryo

1990 • 516 citations

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

1997 • 511 citations

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans

1992 • 503 citations

Sernaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord

1995 • 492 citations

UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues

1996 • 491 citations

The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system

1991 • 432 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

1997 • 372 citations

Earliest sensory nerve fibres are guided to peripheral targets by attractants other than nerve growth factor

1983 • 356 citations

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension

1995 • 352 citations

Axonin-1, Nr-CAM, and Ng-CAM play different roles in the in vivo guidance of chick commissural neurons

1995 • 325 citations

Mutations affecting development of the midline and general body shape during zebrafish embryogenesis

1996 • 287 citations

commissureless Controls Growth Cone Guidance across the CNS Midline in Drosophila and Encodes a Novel Membrane Protein

1996 • 260 citations

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

1993 • 237 citations

Motor Axon Subpopulations Respond Differentially to the Chemorepellents Netrin-1 and Semaphorin D

1997 • 237 citations

Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant

1990 • 227 citations

A family of molecules related to collapsin in the embryonic chick nervous system

1995 • 225 citations

The Role of the Floor Plate in Axon Guidance

1995 • 218 citations

Guidance of commissural growth cones at the floor plate in embryonic rat spinal cord

1990 • 210 citations

Interference with Axonin-1 and NrCAM Interactions Unmasks a Floor-Plate Activity Inhibitory for Commissural Axons

1997 • 187 citations

Control of dorsoventral pattern in vertebrate neural development: induction and polarizing properties of the floor plate

1991 • 177 citations

Patterning the Brain of the Zebrafish Embryo

1993 • 169 citations

Role of the floor plate in axonal patterning in the zebrafish CNS

1992 • 169 citations

Perturbation of neuronal differentiation and axon guidance in the spinal cord of mouse embryos lacking a floor plate: analysis of Danforth’s shorttail mutation

1991 • 168 citations

Tissue explants affecting extension and orientation of axons in cultured chick embryo ganglia*1

1977 • 158 citations

Segmental repetition of neuronal phenotype sets in the chick embryo hindbrain

1993 • 156 citations

Axonal trajectories and distribution of GABAergic spinal neurons in wildtype and mutant zebrafish lacking floor plate cells

1992 • 125 citations

Guidance of Circumferentially Growing Axons by Netrin-Dependent and -Independent Floor Plate Chemotropism in the Vertebrate Brain

1996 • 122 citations

Pathfinding by identified growth cones in the spinal cord of zebrafish embryos

1990 • 112 citations

Neuroanatomical and functional analysis of neural tube formation in notochordless Xenopus embryos; laterality of the ventral spinal cord is lost

1991 • 105 citations

Growth cone guidance by floor plate cells in the spinal cord of zebrafish embryos

1992 • 101 citations

Guidance of cerebellofugal axons in the rat embryo: Directed growth toward the floor plate and subsequent elongation along the longitudinal axis

1995 • 100 citations

Growth cone dynamics during the migration of an identified commissural growth cone

1993 • 99 citations

Midline signaling in the primordium of the zebrafish anterior central nervous system.

1994 • 98 citations

Chemorepulsion of developing motor axons by the floor plate

1995 • 98 citations

Identification of early developing axon projections from spinal interneurons in the chick embryo with a neuron specific β-tubulin antibody: evidence for a new ‘pioneer’ pathway in the spinal cord

1990 • 93 citations

Guidance of Developing Axons by Diffusible Chemoattractants

1990 • 80 citations

Floor plate chemoattracts crossed axons and chemorepels uncrossed axons in the vertebrate brain

1995 • 71 citations

Expression of a lacZ transgene reveals floor plate cell morphology and macromolecular transfer to commissural axons

1993 • 59 citations

An experimental analysis of in vivo guidance cues used by axons of spinal interneurons in the chick embryo: evidence for chemotropism and related guidance mechanisms

1991 • 53 citations

The avian tectobulbar tract: development, explant culture, and effects of antibodies on the pattern of neurite outgrowth

1990 • 49 citations

Cell-cell interactions during the migration of an identified commissural growth cone in the embryonic grasshopper

1993 • 44 citations

The development of brain stem projections to the spinal cord in the chicken embryo

1993 • 33 citations

Axonal outgrowth within the abnormal scaffold of brain tracts in a zebrafish mutant

1994 • 29 citations

The notochord and floor plate guide growth cones in the zebrafish spinal cord

1995 • 28 citations

Early development of efferent projections from the chick tectum

1995 • 13 citations

Guidance of cerebellar plate axons at the floor plate: Experimental manipulation using whole-mount in vitro preparation

1994 • 4 citations

1106 Cerebellofugal Axons Change Responsiveness to a Floor Plate-Derived Chemoattractant After Crossing the Floor Plate

1996 • 3 citations