Ubiquftin mRNA is a major stress-induced transcript in mammalian cells

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli

1984 • 1,608 citations

METALLOTHIONEIN

1986 • 1,606 citations

Dideoxy sequencing method using denatured plasmid templates

1986 • 1,537 citations

Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

1979 • 1,403 citations

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1987 • 850 citations

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

1987 • 731 citations

Differential induction of heat shock, SOS, and oxidation stress regulons and accumulation of nucleotides in Escherichia coli

1987 • 492 citations

Ubiquitin-Mediated Pathways for Intracellular Proteolysis

1987 • 409 citations

Ubiquitin is a heat shock protein in chicken embryo fibroblasts.

1985 • 392 citations

The immunochemical detection and quantitation of intracellular ubiquitin-protein conjugates.

1985 • 383 citations

The human ubiquitin multigene family: some genes contain multiple directly repeated ubiquitin coding sequences.

1985 • 355 citations

Complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells

1975 • 350 citations

Post-transcriptional control of myc and p53 expression during differentiation of the embryonal carcinoma cell line F9

1985 • 274 citations

Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts.

1986 • 215 citations

Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor.

1985 • 196 citations

The human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamily

1987 • 157 citations

Microinjection of ubiquitin: changes in protein degradation in HeLa cells subjected to heat-shock.

1987 • 145 citations

Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells

1971 • 143 citations

The Chicken Ubiquitin Gene Contains a Heat Shock Promoter and Expresses an Unstable mRNA in Heat-Shocked Cells

1986 • 137 citations

Induction of B2 RNA polymerase III transcription by heat shock: enrichment for heat shock induced sequences in rodent cells by hybridization subtraction

1986 • 131 citations

Molecular cloning of sequences encoding the human heat-shock proteins and their expression during hyperthermia

1986 • 129 citations

Ubiquitin Is a Heat Shock Protein in Chicken Embryo Fibroblasts

1985 • 105 citations

Ubiquitin has intrinsic proteolytic activity: implications for cellular regulation.

1987 • 92 citations

DNA damage and heat shock dually regulate genes in Saccharomyces cerevisiae.

1986 • 86 citations

Expression of the yeast UB14 gene increases in response to DNA-damaging agents and in meiosis.

1988 • 84 citations

Isolation, characterization, and amino acid sequence of a ubiquitin-like protein from insect eggs.

1982 • 72 citations

Induction of Metallothionein and Other mRNA Species by Carcinogens and Tumor Promoters in Primary Human Skin Fibroblasts

1986 • 50 citations

Transcriptional induction of the ubiquitin gene during herpes simplex virus infection is dependent upon the viral immediate-early protein ICP4

1987 • 41 citations

Recombination of parent and daughter strand DNA after UV-irradiation in mammalian cells

1983 • 34 citations

DNA Damage and Heat Shock Dually Regulate Genes in Saccharomyces cerevisiae

1986 • 32 citations

Expression of the Yeast UBI4 Gene Increases in Response to DNA-Damaging Agents and in Meiosis

1988 • 25 citations