Nuclear factor-κB is upregulated in colorectal cancer

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Cancer statistics, 2000

2000 • 3,907 citations

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1998 • 2,698 citations

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB

2001 • 1,427 citations

How NF-κB is activated: the role of the IκB kinase (IKK) complex

1999 • 1,133 citations

Signal transduction through NF-κB

1998 • 1,103 citations

Caspases: the proteases of the apoptotic pathway

1998 • 1,048 citations

Constitutive Activation of NF-κB during Progression of Breast Cancer to Hormone-Independent Growth

1997 • 824 citations

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

1997 • 780 citations

Gemcitabine: metabolism, mechanisms of action, and self-potentiation.

1995 • 741 citations

DNA Damaging Agents Induce Expression of Fas Ligand and Subsequent Apoptosis in T Lymphocytes via the Activation of NF-κB and AP-1

1998 • 726 citations

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer.

1997 • 717 citations

The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells.

1999 • 640 citations

Transcriptional Cross Talk between NF-κB and p53

1999 • 590 citations

The transcription factor NF-κB: control of oncogenesis and cancer therapy resistance

2000 • 324 citations

Constitutive Activation of NF-κB in Primary Adult T-Cell Leukemia Cells

1999 • 292 citations

NF-κB to the rescue: RELs, apoptosis and cellular transformation

1999 • 276 citations

Activation of NF-κB by Antineoplastic Agents

1997 • 271 citations

Expression of a dominant-negative mutant inhibitor-kappaBalpha of nuclear factor-kappaB in human head and neck squamous cell carcinoma inhibits survival, proinflammatory cytokine expression, and tumor growth in vivo.

1999 • 265 citations

Inhibition of Nuclear Factor κB Activation Attenuates Apoptosis Resistance in Lymphoid Cells

1998 • 225 citations

Proteasome-Dependent Regulation of p21WAF1/CIP1Expression

1996 • 223 citations

NF-κB-mediated Induction of mdr1b Expression by Insulin in Rat Hepatoma Cells

1997 • 191 citations

Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation.

2000 • 160 citations

Nuclear factor-kappaB/IkappaB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells.

2000 • 159 citations

The role of NF-κB/IκB proteins in cancer: implications for novel treatment strategies

1999 • 129 citations

Regulation of NF-κB activity by IκB-related proteins in adenocarcinoma cells

1999 • 113 citations

Inhibition of NF-κB sensitizes non–small cell lung cancer cells to chemotherapy-induced apoptosis

2000 • 109 citations

Stable inhibition of nuclear factor kappaB in cancer cells does not increase sensitivity to cytotoxic drugs.

1999 • 88 citations

Caspase-3–Dependent Organ Apoptosis Early After Burn Injury

1999 • 67 citations

Introduction: Gemcitabine - Status of preclinical studies and perspectives for future clinical applications of this novel nucleoside analog

1995 • 16 citations

Apoptosis in cancer: therapeutic implications.

2000 • 14 citations