Anxiolytic potential of sulpiride, clozapine and derivatives in the open-field test

Tests for emotionality in rats and mice: A review

1973 • 1,561 citations

Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines

1981 • 509 citations

Animal models for the study of anti-anxiety agents: A review

1985 • 457 citations

Two independent behavioral dimensions in open-field performance.

1967 • 431 citations

Action of drugs of abuse on brain reward systems

1980 • 330 citations

Haloperidol-induced catalepsy is mediated by postsynaptic dopamine receptors

1980 • 311 citations

Agranulocytosis during treatment with clozapine

1977 • 229 citations

Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine

1975 • 206 citations

Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: Evidence for two different mechanisms of action

1978 • 198 citations

Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons

1985 • 196 citations

Dopamine receptor antagonism by the novel antianxiety drug, buspirone

1983 • 159 citations

Disinhibitory effects of buspirone and low doses of sulpiride and haloperidol in two experimental anxiety models in rats: Possible role of dopamine

1986 • 143 citations

Pharmacologic Treatment of Agitation Associated With Dementia

1986 • 123 citations

Dopamine and antianxiety activity

1982 • 114 citations

The Benzodiazepines: From molecular biology to clinical practice

1983 • 112 citations

Effect of single and repeated administration of clozapine on the metabolism of dopamine and noradrenaline in the brain of the rat

1974 • 96 citations

Effects of single and long-term haloperidol administration on open field behavior of rats

1981 • 93 citations

Low-Dose Neuroleptic Regimens in the Treatment of Borderline Patients

1979 • 92 citations

The Affective disorders

1983 • 89 citations

Chemistry and Pharmacology of the 1,4-Benzodiazepines

1974 • 87 citations

Clozapine—A serotonin antagonist?

1984 • 81 citations

Dopamine D2 receptors and dopamine metabolismRelationship between biochemical and behavioural effects of substituted benzamide drugs

1986 • 70 citations

The involvement of nigral serotonin innervation in the control of punishment-induced behavioral inhibition in rats

1983 • 56 citations

Studies on the interaction between cerebral 5‐hydroxytryptamine and γ‐aminobutyric acid in the mode of action of diazepam in the rat

1983 • 54 citations

Diazepam-induced decrease in histamine turnover in mouse brain

1986 • 54 citations

Use of DRL in differentiating anxiolytic and neuroleptic properties of CNS drugs

1977 • 50 citations

Changes in ambulatory activities and muscle relaxation in rats after repeated doses of diazepam

1982 • 50 citations

Effects of repeated administration of chlordiazepoxide on spontaneous locomotor activity in mice

1979 • 50 citations

Effects of acute diazepam and clobazam on spontaneous locomotor activity and central amine metabolism in rats

1977 • 50 citations

No cross-tolerance between the stimulatory and depressant actions of benzodiazepines in mice

1985 • 45 citations

An analysis of drug effects in mice exposed to a simple novel environment

1972 • 42 citations

Haloperidol-induced emotional defecation: a possible model for neuroleptic anxiety syndrome

1987 • 42 citations

Stimulation of rat spontaneous locomotion by low doses of haloperidol and (−)-sulpiride: Importance of animal selection and measurement technique

1983 • 35 citations

Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission

1986 • 35 citations

Clozapine in the treatment of schizophrenic patients: an international multicenter trial.

1987 • 33 citations

EFFECTS OF METHYLPHENIDYLACETATE AND CHLORPROMAZINE ON CERTAIN COMPONENTS OF GENERAL ACTIVITY¹

1959 • 30 citations

Synthesis of clozapine analogs and their affinity for clozapine and spiroperidol binding sites in rat brain

1981 • 27 citations

A comparison of the effects of RO15,1788 and chlordiazepoxide on hot-plate latencies, acoustic startle, and locomotor activity

1986 • 25 citations

Effects of 5-hydroxytryptamine on defecation in open-field behavior in rats

1980 • 24 citations

Acute thioridazine stimulates mesolimbic but not nigrostriatal dopamine release: demonstration by in vivo electrochemistry

1987 • 23 citations

A comparison of clozapine, chlorpromazine, and thioridazine upon DRL performance in the squirrel monkey

1979 • 22 citations

Assessment of Low Dosage Haloperidol in Anxiety States

1971 • 19 citations

An automatic device for measuring speed of movement and time spent at rest: Its application to testing dopaminergic drugs

1986 • 16 citations

Effects of the administration of two doses of sulpiride on the behaviour of the rat

1976 • 16 citations

Chlordiazepoxide effects on reactions to novelty and activity with and without prior drug experience

1975 • 15 citations

The effects of some atypical neuroleptics on apomorphine-induced behaviors as a measure of their relative potencies in blocking presynaptic versus postsynaptic dopamine receptors

1986 • 14 citations

Neurobehavioral evidence for mesolimbic specificity of action by clozapine: studies using electrical intracranial self-stimulation.

1983 • 14 citations

Potentiation of the effects of chlorpromazine on exploration in the rat by a prior experience of the drug

1973 • 14 citations

Underrecognized and Underresearched Side Effects of Neuroleptics

1989 • 14 citations

Effects of N-(ethyl-2 pyrrolidinyl-methyl)-2-methoxy-5-sulfamoil-benzamide (sulpyrid) on the central nervous system in rats and mice

1972 • 13 citations

A biphasic effect of chlordiazepoxide on animal locomotor activity

1984 • 13 citations

Haloperidol produces increased defecation in rats in habituated environments

1987 • 13 citations

Cataleptogenic potency of the antipsychotic drugs is inversely correlated with neuronal activity in the amygdaloid complex of the rat

1983 • 12 citations

Operant Conditioning and Haloperidol-Induced Hypokinetic Effects

1987 • 11 citations

A microgram dose of diazepam produces specific inhibition of ambulation in the rat

1985 • 10 citations

[Action of some psychotropic drugs on emotional defecation in mice].

1970 • 9 citations

Lack of effects of apomorphine, haloperidol and clozapine on the synthesis and utilization of brain GABA

1987 • 6 citations

The involvement of monoaminergic and GABAergic systems in locomotor inhibition produced by clobazam and diazepam in rats.

1982 • 4 citations

Action du sulpiride sur le comportement operant chez l'animal

1975 • 2 citations

Same or different?. An exploration of the behavioral effects of benzamides

2011 • 1 citations