Conservation of pericentromeric duplications of a 200-kb part of the human 21q22.1 region in primates

A new bacteriophage P1–derived vector for the propagation of large human DNA fragments

1994 • 857 citations

EVOLUTION FROM FISH TO MAMMALS BY GENE DUPLICATION

2009 • 709 citations

Evolution of the Vertebrate Genome as Reflected in Paralogous Chromosomal Regions in Man and the House Mouse

1993 • 475 citations

Molecular phylogeny of the hominoids: inferences from multiple independent DNA sequence data sets

1997 • 329 citations

Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome.

1989 • 261 citations

Evolution of the primate lineage leading to modern humans: Phylogenetic and demographic inferences from DNA sequences

1997 • 186 citations

Pattern and timing of evolutionary divergences among hominoids based on analyses of complete mtDNAs

1996 • 162 citations

Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries.

1991 • 160 citations

Duplication of a gene-rich cluster between 16p11.1 and Xq28: a novel pericentromeric-directed mechanism for paralogous genome evolution

1996 • 154 citations

Evolutionary rates of insertion and deletion in noncoding nucleotide sequences of primates.

1994 • 111 citations

Transcriptional Map of the 2.5-Mb CBR–ERG Region of Chromosome 21 Involved in Down Syndrome

1998 • 47 citations

Two Sequence-Ready Contigs Spanning the Two Copies of a 200-kb Duplication on Human 21q: Partial Sequence and Polymorphisms

1998 • 23 citations

Cloning and Characterization of a 135- to 500-kb Region of Homology on the Long Arm of Human Chromosome 21

1994 • 20 citations

A one-step efficient and specific non-radioactive non-fluorescent method for in situ hybridization of banded chromosomes

1990 • 19 citations

Simplified large-scale alkaline lysis preparation of plasmid DNA with minimal use of phenol.

1994 • 13 citations

Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21

1992 • 10 citations

Use of YAC fragmentation to delimit a duplicated region on human Chromosome 21

1996 • 9 citations

Physical mapping of chromosome 21 DNA markers in Alzheimer's disease region using somatic cell hybrids

1990 • 9 citations