Duplication of a gene-rich cluster between 16p11.1 and Xq28: a novel pericentromeric-directed mechanism for paralogous genome evolution

Evolution by gene duplication

1970 • 5,849 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

High resolution of human evolutionary trees with polymorphic microsatellites

1994 • 1,868 citations

Molecular drive: a cohesive mode of species evolution

1982 • 1,579 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

1989 • 939 citations

A sodium-potassium switch in the formation of four-stranded G4-DNA

1990 • 789 citations

The evolution of genes: the chicken preproinsulin gene

1980 • 725 citations

EVOLUTION FROM FISH TO MAMMALS BY GENE DUPLICATION

2009 • 709 citations

Locating protein-coding regions in human DNA sequences by a multiple sensor-neural network approach.

1991 • 665 citations

Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs.

1995 • 600 citations

Archetypal organization of the amphioxus Hox gene cluster

1994 • 574 citations

Evolution of the Vertebrate Genome as Reflected in Paralogous Chromosomal Regions in Man and the House Mouse

1993 • 475 citations

Gene number, noise reduction and biological complexity

1995 • 462 citations

Recombination at the human α-globin gene cluster: Sequence features and topological constraints

1987 • 345 citations

A sequence assembly and editing program for efficient management of large projects

1991 • 322 citations

Circular DNA is excised by immunoglobulin class switch recombination

1990 • 244 citations

DNA Sequences Mediating Class Switching in α-Immunoglobulins

1980 • 243 citations

Switch circular DNA formed in cytokine-treated mouse splenocytes: Evidence for intramolecular DNA deletion in immunoglobulin class switching

1990 • 240 citations

Hypervariable minisatellite DNA is a hotspot for homologous recombination in human cells

1990 • 226 citations

Evolution of the differential regulation of duplicate genes after polyploidization

1979 • 208 citations

Potential genetic functions of tandem repeated DNA sequence blocks in the human genome are based on a highly conserved ?chromatin folding code?

1990 • 207 citations

Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire

1994 • 199 citations

Characterization of a highly unstable mouse minisatellite locus: Evidence for somatic mutation during early development

1989 • 196 citations

Evolution of the insulin superfamily: cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus.

1990 • 192 citations

Isolation of a GCC repeat showing expansion in FRAXF, a fragile site distal to FRAXA and FRAXE

1994 • 167 citations

Cloning, pharmacological characterization, and genomic localization of the human creatine transporter.

1994 • 147 citations

Report of the committee on the genetic constitution of chromosomes 10, 11, and 12

1987 • 146 citations

Gene duplication in tetraploid fish: model for gene silencing at unlinked duplicated loci.

1978 • 141 citations

Formation of large deletions by illegitimate recombination in the HPRT gene of primary human fibroblasts.

1993 • 135 citations

Physical mapping of human chromosomes by repetitive sequence fingerprinting.

1990 • 132 citations

The Cloning and Expression of a Human Creatine Transporter

1994 • 131 citations

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

1993 • 130 citations

Diversification of the Wnt gene family on the ancestral lineage of vertebrates.

1992 • 127 citations

The human minisatellite consensus at breakpoints of oncogene translocations

1990 • 111 citations

Isolation and characterization of a MAGE gene family in the Xp21.3 region.

1995 • 106 citations

Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements.

1988 • 96 citations

DNA turnover and the molecular clock

1987 • 94 citations

Genomic Organization of the Adrenoleukodystrophy Gene

1994 • 80 citations

Complete nucleotide sequence of the rabbit β-like globin gene cluster

1989 • 73 citations

Report of the sixth international workshop on X chromosome mapping 1995

1995 • 72 citations

The Pregnancy-Specific Glycoprotein (PSG) Gene Cluster on Human Chromosome 19: Fine Structure of the 11 PSG Genes and Identification of 6 New Genes Forming a Third Subgroup within the Carcinoembryonic Antigen (CEA) Family

1994 • 71 citations

Extensive cross-homology between the long and the short arm of chromosome 16 may explain leukemic inversions and translocations

1992 • 64 citations

Structure and Expression of the Human Lysyl Hydroxylase Gene (PLOD): Introns 9 and 16 Contain Alu Sequences at the Sites of Recombination in Ehlers-Danlos Syndrome Type VI Patients

1994 • 59 citations

A simple and rapid preparation of M13 sequencing templates for manual and automated dideoxy sequencing

1987 • 55 citations

Evaluation of a cosmid contig physical map of human chromosome 16

1992 • 54 citations

Construction and characterization of partial digest DNA libraries made from flow-sorted human chromosome 16

1993 • 47 citations

A novel human DNA polymorphism resulting from transfer of DNA from chromosome 6 to chromosome 16

1990 • 45 citations

Duplication in the hypoxanthine phosphoribosyl-transferase gene caused by Alu-Alu recombination in a patient with Lesch Nyhan syndrome

1993 • 43 citations

Optimization of asymmetric polymerase chain reaction for rapid fluorescent DNA sequencing.

1990 • 40 citations

The Gene Clusters ARC and COR on Chromosomes 5 and 10, Respectively, of Saccharomyces cerevisiae Share a Common Ancestry

1993 • 38 citations

The complete murine immunoglobulin class switch region of the alpha heavy chain gene-hierarchic repetitive structure and recombination breakpoints.

1993 • 31 citations

Chromosome 16-specific repetitive DNA sequences that map to chromosomal regions known to undergo breakage/ rearrangement in leukemia cells

1992 • 25 citations

A New Human Gene (DXS1357E) with Ubiquitous Expression, Located in Xq28 Adjacent to the Adrenoleukodystrophy Gene

1994 • 24 citations

Isolation of chromosome-specific genes by reciprocal probing of arrayed cDNA and cosmid libraries

1995 • 19 citations

Large-Scale Sequencing Library Production: An Adapter-Based Strategy

1993 • 19 citations

A simple protocol for the automation of DNA cycle sequencing reactions and polymerase chain reactions

1992 • 18 citations

Discovering sequence similarity by the algorithmic significance method.

1993 • 18 citations

PCR Based Strategies for Gap Closure in Large-scale Sequencing Projects

1994 • 16 citations

The human myoglobin gene: a third dispersed globin locus in the human genome

1984 • 14 citations

Targeting and Regulation of Immunoglobulin Gene Somatic Hypermutation and lsotype Switch Recombination

1995 • 14 citations

A 2.3-Mb Yeast Artificial Chromosome Contig Spanning from Gabra3 to G6pd on the Mouse X Chromosome

1994 • 14 citations

Comparative mapping of a gorilla-derived alpha satellite DNA clone on great ape and human chromosomes

1991 • 14 citations

Organization and Expression of Homeobox Genes in Mouse and Man^a

1989 • 11 citations