A Heterozygous Deletion of the Autoimmune Regulator (AIRE1) Gene, Autoimmune Thyroid Disease, and Type 1 Diabetes: No Evidence for Association¹

Positional cloning of the APECED gene

1997 • 1,385 citations

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1997 • 1,155 citations

Clinical Variation of Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED) in a Series of 68 Patients

1990 • 1,041 citations

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

1996 • 794 citations

CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population.

1995 • 426 citations

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

1997 • 408 citations

CTLA4 Alanine-17 Confers Genetic Susceptibility to Graves’ Disease and to Type 1 Diabetes Mellitus¹

1997 • 408 citations

A search for type 1 diabetes susceptibility genes in families from the United Kingdom

1998 • 329 citations

A CTLA‐4 gene polymorphism is associated with both Graves' disease and autoimmune hypothyroidism

1997 • 261 citations

Codon 17 Polymorphism of the Cytotoxic T Lymphocyte Antigen 4 Gene in Hashimoto’s Thyroiditis and Addison’s Disease1

1997 • 242 citations

Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17α-hydroxylase

1992 • 201 citations

A Common and Recurrent 13-bp Deletion in the Autoimmune Regulator Gene in British Kindreds with Autoimmune Polyendocrinopathy Type 1

1998 • 198 citations

Autoantibodies to cytochrome P450 enzymes P450scc, P450c17, and P450c21 in autoimmune polyglandular disease types I and II and in isolated Addison's disease.

1994 • 182 citations

Gene defect behind APECED: a new clue to autoimmunity

1998 • 154 citations

The Development of Graves’ Disease and theCTLA-4Gene on Chromosome 2q33¹

1999 • 154 citations

From genome to aetiology in a multifactorial disease, type 1 diabetes

1999 • 143 citations

Linkage Disequilibrium between the Human Leukocyte Antigen Class II Region of the Major Histocompatibility Complex and Graves’ Disease: Replication Using a Population Case Control and Family-Based Study1

1998 • 140 citations

Autoantibodies against Aromatic<scp>l</scp>-Amino Acid Decarboxylase in Autoimmune Polyendocrine Syndrome Type I¹

1997 • 124 citations

Genetic Susceptibility to the Development of Autoimmune Disease

1997 • 115 citations

Linkage Analysis of Candidate Genes in Autoimmune Thyroid Disease. II. Selected Gender-Related Genes and the X-Chromosome

1998 • 109 citations

A cytotoxic T lymphocyte antigen‐4 (CTLA‐4) gene polymorphism is associated with autoimmune Addison's disease in English patients

1998 • 109 citations

A New Graves Disease–Susceptibility Locus Maps To Chromosome 20q11.2

1998 • 102 citations

Autoantibodies against a novel 51 kDa islet antigen and glutamate decarboxylase isoforms in autoimmune polyendocrine syndrome type I

1994 • 61 citations

Linkage Analysis of Candidate Genes in Autoimmune Thyroid Disease. II. Selected Gender-Related Genes and the X-Chromosome1

1998 • 52 citations

Linkage Analysis of Candidate Genes in Autoimmune Thyroid Disease. III. Detailed Analysis of Chromosome 14 Localizes Graves’ Disease-1 (GD-1) Close to Multinodular Goiter-1 (MNG-1)¹

1998 • 46 citations