Effect of Fasting on Insulin-Like Growth Factor (IGF)-IA and IGF-IB Messenger Ribonucleic Acids and Prehormones in Rat Liver*

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Fast and sensitive silver staining of DNA in polyacrylamide gels

1991 • 2,914 citations

Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

1989 • 1,796 citations

Nutritional Regulation of the Insulin-Like Growth Factors*

1994 • 1,537 citations

The nucleotide sequence of the rat cytoplasmic β–actin gene

1983 • 1,059 citations

[31] Use of protein A—bearing staphylococci for the immunoprecipitation and isolation of antigens from cells

1981 • 307 citations

Differential expression of alternative 5' untranslated regions in mRNAs encoding rat insulin-like growth factor I.

1987 • 292 citations

Mosaic evolution of the insulin-like growth factors. Organization, sequence, and expression of the rat insulin-like growth factor I gene.

1987 • 279 citations

Molecular Cloning of Rat Insulin-Like Growth Factor I Complementary Deoxyribonucleic Acids: Differential Messenger Ribonucleic Acid Processing and Regulation by Growth Hormone in Extrahepatic Tissues

1987 • 275 citations

Distribution and Regulation of Rat Insulin-Like Growth Factor I Messenger Ribonucleic Acids Encoding Alternative Carboxyterminal E-Peptides: Evidence for Differential Processing and Regulation in Liver

1988 • 224 citations

Regulation by fasting of rat insulin-like growth factor I and its receptor. Effects on gene expression and binding.

1989 • 208 citations

Effect of Fasting on Insulin-Like Growth Factor-I (IGF-I) and Growth Hormone Receptor mRNA Levels and IGF-I Gene Transcription in Rat Liver

1990 • 182 citations

Nutritional regulation of hormones and growth factors that control mammalian growth

1994 • 159 citations

Plasma somatomedin-C in fasted and refed rats: close relationship with changes in liver somatogenic but not lactogenic binding sites

1983 • 153 citations

Effect of Dietary Protein Deprivation on Insulin-Like Growth Factor (IGF)-I and -II, IGF Binding Protein-2, and Serum Albumin Gene Expression in Rat*

1990 • 148 citations

Regulation of Start Site Usage in the Leader Exons of the Rat Insulin-Like Growth Factor-I Gene by Development, Fasting, and Diabetes

1991 • 141 citations

NUTRITIONALLY-INDUCED CHANGES IN HEPATIC INSULIN-LIKE GROWTH FACTOR I (IGF-I) GENE EXPRESSION IN RATS.

1987 • 140 citations

Regulation of Somatomedin-C/Insulin-Like Growth Factor I by Nutrients

1986 • 132 citations

Serum Concentrations of Insulin-Like Growth Factor II Are Not Changed by Short Term Fasting And Refeeding*

1988 • 125 citations

Differential regulation of transcription initiation from insulin-like growth factor-I (IGF-I) leader exons and of tissue IGF-I expression in response to changed growth hormone and nutritional status in sheep.

1993 • 121 citations

Failure of Insulin-Like Growth Factor-I (IGF-I) Infusion to Promote Growth in Protein-Restricted Rats Despite Normalization of Serum IGF-I Concentrations*

1991 • 112 citations

Tissue and Development Specific Regulation of a Complex Family of Rat Insulin-Like Growth Factor I Messenger Ribonucleic Acids

1988 • 111 citations

Isolation of Rat Testis cDNAs Encoding an Insulin-Like Growth Factor I Precursor

1987 • 105 citations

Reduced serum concentrations of insulin-like growth factor-I (IGF-I) in protein-restricted growing rats are accompanied by reduced IGF-I mRNA levels in liver and skeletal muscle

1991 • 95 citations

Evidence That Pretranslational and Translational Defects Decrease Serum Insulin-Like Growth Factor-I Concentrations during Dietary Protein Restriction*

1991 • 94 citations

Effect of dietary proteins on insulin-like growth factor-1 (IGF-1) messenger ribonucleic acid content in rat liver

1992 • 90 citations

The Size Heterogeneity of Rat Insulin-Like Growth Factor-I mRNAs is Due Primarily to Differences in the Length of 3′-Untranslated Sequence

1989 • 73 citations

Growth Hormone and Nutrition

1992 • 73 citations

Alternative leader sequences in insulin-like growth factor I mRNAs modulate translational efficiency and encode multiple signal peptides.

1995 • 67 citations

The decreased plasma concentration of insulin-like growth factor-I in protein-restricted rats is not due to decreased numbers of growth hormone receptors on isolated hepatocytes

1990 • 67 citations

Specific Decrease in Liver Insulin-Like Growth Factor-I and Brain Insulin-Like Growth Factor-II Gene Expression in Energy-Restricted Rats

1991 • 65 citations

Decreased serum insulin-like growth factor I response to growth hormone in hypophysectomized rats fed a low protein diet: evidence for a postreceptor defect

1988 • 64 citations

Reduction of insulin-like growth factor-I (IGF-I) in protein-restricted rats is associated with differential regulation of IGF-binding protein messenger ribonucleic acids in liver and kidney, and peptides in liver and serum.

1994 • 64 citations

Alternative Splicing Produces Messenger RNAs Encoding Insulin-Like Growth Factor-I Prohormones that Are Differentially Glycosylatedin Vitro

1990 • 53 citations

Translational status of the insulin-like growth factor-I mRNAs in liver of protein-restricted rats

1992 • 37 citations

Multiple Transcription Start Sites in the Rat Insulin-Like Growth Factor-I Gene Give Rise to IGF-I mRNAs that Encode Different IGF-I Precursors and are Processed DifferentlyIn Vitvo

1993 • 32 citations

Structural Characterization of Exon 6 of the Rat IGF-I Gene

1992 • 29 citations

Differential polysomal localization of human insulin‐like‐growth‐factor‐2 mRNAs in cell lines and foetal liver

1994 • 29 citations

Effect of the Quantity and Nutritional Quality of Dietary Proteins on the Transcriptional Activity of Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-1 Genes

1993 • 11 citations