Adhesion molecules mediating neutrophil migration to arthritis in vivo and across endothelium and connective tissue barriers in vitro

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration

1995 • 1,525 citations

Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro.

1989 • 1,115 citations

α4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1995 • 1,018 citations

The selecting: vascular adhesion molecules

1995 • 954 citations

The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.

1995 • 716 citations

Leukocyte Trafficking Mediated by Selectin-Carbohydrate Interactions

1995 • 648 citations

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization.

1989 • 627 citations

Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells [published erratum appears in Blood 1990 Dec 1;76(11):2420]

1990 • 540 citations

A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo

1987 • 525 citations

Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies.

1986 • 423 citations

Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP-140).

1992 • 385 citations

Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA‐1 subunit‐specific monoclonal antibodies

1991 • 233 citations

Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA-4. Correlation with distinct alpha 4 epitopes

1991 • 231 citations

Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody. A likely role for VLA-4 in vivo.

1991 • 211 citations

The role of PECAM-1 (CD31) in leukocyte emigration: studies in vitro and in vivo

1995 • 183 citations

A novel β ₁ ‐dependent adhesion pathway on neutrophils: a mechanism invoked by dihydrocytochalasin B or endothelial transmigration

1995 • 180 citations

VLA-4 integrin can mediate CD11/CD18-independent transendothelial migration of human monocytes.

1993 • 163 citations

Monoclonal Antibodies to the Leukocyte Membrane CD18 Glycoprotein Complex and to Intercellular Adhesion Molecule-1 Inhibit Leukocyte-Endothelial Adhesion in Rabbits

1991 • 153 citations

The alpha 4-integrin supports leukocyte rolling and adhesion in chronically inflamed postcapillary venules in vivo.

1996 • 148 citations

Rat blood neutrophils express very late antigen 4 and it mediates migration to arthritic joint and dermal inflammation.

1996 • 141 citations

Monocytes use either CD11/CD18 or VLA-4 to migrate across human endothelium in vitro.

1994 • 128 citations

Insights into Selectin Function from Knockout Mice

1997 • 123 citations

Effect of a new monoclonal antibody, TA-2, that inhibits lymphocyte adherence to cytokine stimulated endothelium in the rat.

1991 • 116 citations

The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat.

1992 • 98 citations

CD11/CD18-independent neutrophil adherence to laminin is mediated by the integrin VLA-6

1992 • 93 citations

Divalent cation substitution reveals CD18- and very late antigen-dependent pathways that mediate human neutrophil adherence to fibronectin.

1992 • 88 citations

Characterization of rat LECAM‐1 (L‐selectin) by the use of monoclonal antibodies and evidence for the presence of soluble LECAM‐1 in rat sera

1993 • 84 citations

CD11/CD18-independent transendothelial migration of human polymorphonuclear leukocytes and monocytes: involvement of distinct and unique mechanisms

1995 • 83 citations

Genetic manipulation of vascular adhesion molecules in mice.

1996 • 72 citations

Characterization of a Novel Adhesion Function Blocking Monoclonal Antibody to Rat/Mouse P-Selectin Generated in the P-Selectin-Deficient Mouse

1997 • 67 citations

Treatment of established adjuvant arthritis in rats with monoclonal antibody to CD18 and very late activation antigen‐4 integrins suppresses neutrophil and T‐lymphocyte migration to the joints and improves clinical disease

1996 • 65 citations

Second Generation Monoclonal Antibodies to the Human Integrin α⁶β₄

1990 • 61 citations

Migration of Human Polymorphonuclear Leukocytes through a Synovial Fibroblast Barrier Is Mediated by both β2 (CD11/CD18) Integrins and the β1 (CD29) Integrins VLA-5 and VLA-6

1995 • 57 citations

A blocking monoclonal antibody to endothelial-leukocyte adhesion molecule-1 (ELAM1)

1990 • 54 citations

Inhibition of lymphocyte endothelial adhesion and in vivo lymphocyte migration to cutaneous inflammation by TA-3, a new monoclonal antibody to rat LFA-1.

1992 • 54 citations

The role of E‐ and P‐selectin in neutrophil and monocyte migration in adjuvant‐induced arthritis in the rat

1997 • 47 citations

β₂ (CD18) and β₁ (CD29) integrin mechanisms in migration of human polymorphonuclear leucocytes and monocytes through lung fibroblast barriers: shared and distinct mechanisms

1997 • 47 citations

The β1 integrin, very late activation antigen‐4 on human neutrophils can contribute to neutrophil migration through connective tissue fibroblast barriers

1997 • 45 citations

Mac‐1 (CD11b/CD18) is the predominant β₂ (CD18) integrin mediating human neutrophil migration through synovial and dermal fibroblast barriers

1996 • 40 citations

Generation and Characterization of a Novel Adhesion Function Blocking Monoclonal Antibody Recognizing Both Rat and Mouse E-Selectin

1997 • 38 citations

A Major Portion of Polymorphonuclear Leukocyte and T Lymphocyte Migration to Arthritic Joints in the Rat Is via LFA-1/MAC-1-Independent Mechanisms

1993 • 36 citations

Role of E‐ and P‐selectin in migration of monocytes and polymorphonuclear leucocytes to cytokine and chemoattractant‐induced cutaneous inflammation in the rat

1997 • 29 citations