Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist

Learned helplessness: Theory and evidence.

1976 • 2,255 citations

Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study

1983 • 1,954 citations

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

1984 • 1,490 citations

The validity of animal models of depression

1984 • 1,365 citations

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1990 • 1,362 citations

Physiology and pharmacology of corticotropin-releasing factor.

1991 • 1,138 citations

Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus

1983 • 595 citations

Alterations in corticotropin-releasing factor-like immunoreactivity in discrete rat brain regions after acute and chronic stress

1986 • 466 citations

Depression: The predisposing influence of stress

1982 • 431 citations

The role of the amygdala in fear-potentiated startle: implications for animal models of anxiety

1992 • 425 citations

Modifications of the Serotonin System by Antidepressant Treatments

1987 • 413 citations

Specificity of the learned helplessness model of depression

1982 • 383 citations

CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors.

1996 • 375 citations

Long-term antidepressant administration alters corticotropin-releasing hormone, tyrosine hydroxylase, and mineralocorticoid receptor gene expression in rat brain. Therapeutic implications.

1991 • 338 citations

The Locus Coeruleus as a Site for Integrating Corticotropin‐Releasing Factor and Noradrenergic Mediation of Stress Responsesa

1993 • 297 citations

Neuropeptide Concentrations in the Cerebrospinal Fluid of Depressed Patients Treated with Electroconvulsive Therapy

1991 • 253 citations

The antidepressants fluoxetine, idazoxan and phenelzine alter corticotropin-releasing hormone and tyrosine hydroxylase mRNA levels in rat brain: therapeutic implications

1992 • 238 citations

The Role of Corticotropin‐Releasing Factor in Behavioural Responses to Stress

2007 • 235 citations

Psychological stress-induced accelerated colonic transit in rats involves hypothalamic corticotropin-releasing factor

1993 • 166 citations

Corticotropin-Releasing Factor: Evidence for a Neurotransmitter Role in the Locus ceruleus during Hemodynamic Stress

1988 • 157 citations

Reversal of learned helplessness by imipramine.

1979 • 153 citations

Desmethylimipramine (DMI) counteracts learned helplessness in rats

1979 • 98 citations

Chronic desipramine and fluoxetine differentially affect extracellular dopamine in the rat prefrontal cortex

1996 • 89 citations

Stress, antidepressant drugs, and the locus coeruleus

1994 • 85 citations

Hypothalamic‐Pituitary‐Adrenal Axis and Suicide

1986 • 71 citations

Reevaluation of the regulation of beta-adrenergic receptor binding by desipramine treatment.

1989 • 55 citations

Melancholia in rodents: neurobiology and pharmacology.

1985 • 50 citations

Learned helplessness sensitizes hippocampal norepinephrine to mild restress

1994 • 43 citations

Effects of acute and chronic administration of desmethylimipramine on the content of norepinephrine and other monoamines in the rat brain

1973 • 39 citations

Treatment of the Irritable Bowel Syndrome

1991 • 24 citations

Reversal of learned helplessness by nortriptyline

1981 • 20 citations

Chronic imipramine treatment induces downregulation of alpha-2 receptors in rat's locus coeruleus and A2 region of the tractus solitarius

1995 • 15 citations

Deleted Work

1955 • 0 citations