Subversion of Cellular Autophagosomal Machinery by RNA Viruses

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

2015 • 15,801 citations

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

2000 • 6,302 citations

Mechanisms of Neuroprotective Action of Vitamin D₃

2004 • 5,057 citations

Development by Self-Digestion

2004 • 3,562 citations

Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages

2004 • 2,135 citations

Death by design: apoptosis, necrosis and autophagy

2004 • 1,330 citations

3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

1982 • 1,313 citations

Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells

2001 • 1,310 citations

Autophagy Defends Cells Against Invading Group A Streptococcus

2004 • 1,042 citations

The molecular machinery of autophagy: unanswered questions

2004 • 900 citations

Methods for monitoring autophagy

2004 • 882 citations

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

2000 • 873 citations

Autophagosome Formation in Mammalian Cells.

2002 • 845 citations

Escape of Intracellular Shigella from Autophagy

2004 • 798 citations

Studies on the mechanisms of autophagy: formation of the autophagic vacuole.

1990 • 789 citations

Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway

2001 • 705 citations

Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles.

1995 • 694 citations

Cloned Poliovirus Complementary DNA Is Infectious in Mammalian Cells

1981 • 686 citations

Phosphorylation of Ribosomal Protein S6 Is Inhibitory for Autophagy in Isolated Rat Hepatocytes

1995 • 654 citations

Regulation and role of autophagy in mammalian cells

2004 • 602 citations

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

1995 • 556 citations

Autophagy in the Eukaryotic Cell

2002 • 534 citations

The Molecular Mechanism of Autophagy

2003 • 519 citations

A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation

2001 • 511 citations

Remodeling the Endoplasmic Reticulum by Poliovirus Infection and by Individual Viral Proteins: an Autophagy-Like Origin for Virus-Induced Vesicles

2000 • 498 citations

Golgi dispersal during microtubule disruption: regeneration of Golgi stacks at peripheral endoplasmic reticulum exit sites.

1996 • 498 citations

Infectious HIV-1 assembles in late endosomes in primary macrophages

2003 • 477 citations

Autophagy: Many paths to the same end

2004 • 474 citations

Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

2003 • 448 citations

Vps27 recruits ESCRT machinery to endosomes during MVB sorting

2003 • 445 citations

Coronavirus Replication Complex Formation Utilizes Components of Cellular Autophagy

2004 • 441 citations

Cellular autophagy: surrender, avoidance and subversion by microorganisms

2004 • 435 citations

RNA Replication of Mouse Hepatitis Virus Takes Place at Double-Membrane Vesicles

2002 • 422 citations

Ultrastructural Characterization of SARS Coronavirus

2004 • 415 citations

Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure.

1995 • 387 citations

Cellular origin and ultrastructure of membranes induced during poliovirus infection

1996 • 376 citations

Autophagy, Cytoplasm-to-Vacuole Targeting Pathway, and Pexophagy in Yeast and Mammalian Cells

2000 • 359 citations

Studies on the mechanisms of autophagy: maturation of the autophagic vacuole.

1990 • 352 citations

Autophagosome Requires Specific Early Sec Proteins for Its Formation and NSF/SNARE for Vacuolar Fusion

2001 • 348 citations

Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A.

1995 • 324 citations

Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments

2000 • 311 citations

Membrane Rearrangement and Vesicle Induction by Recombinant Poliovirus 2C and 2BC in Human Cells

1994 • 309 citations

Electron microscopic study of the formation of poliovirus

1965 • 303 citations

Open Reading Frame 1a-Encoded Subunits of the Arterivirus Replicase Induce Endoplasmic Reticulum-Derived Double-Membrane Vesicles Which Carry the Viral Replication Complex

1999 • 287 citations

Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B

1994 • 278 citations

Association of polioviral proteins of the P2 genomic region with the viral replication complex and virus-induced membrane synthesis as visualized by electron microscopic immunocytochemistry and autoradiography

1987 • 274 citations

Post-translational Modifications of Three Members of the Human MAP1LC3 Family and Detection of a Novel Type of Modification for MAP1LC3B

2003 • 268 citations

Human Apg3p/Aut1p Homologue Is an Authentic E2 Enzyme for Multiple Substrates, GATE-16, GABARAP, and MAP-LC3, and Facilitates the Conjugation of hApg12p to hApg5p

2002 • 268 citations

Cell-Type-Dependent Targeting of Human Immunodeficiency Virus Type 1 Assembly to the Plasma Membrane and the Multivesicular Body

2004 • 260 citations

HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein

2003 • 248 citations

Autophagic programmed cell death in Drosophila

2003 • 223 citations

Cellular COPII Proteins Are Involved in Production of the Vesicles That Form the Poliovirus Replication Complex

2001 • 212 citations

Complete vesiculation of Golgi membranes and inhibition of protein transport by a novel sea sponge metabolite, ilimaquinone

1993 • 210 citations

Leucine Limitation Induces Autophagy and Activation of Lysosome-dependent Proteolysis in C2C12 Myotubes through a Mammalian Target of Rapamycin-independent Signaling Pathway

2000 • 198 citations

Regulation of Translational Effectors by Amino Acid and Mammalian Target of Rapamycin Signaling Pathways

1999 • 197 citations

Functional Coupling between Replication and Packaging of Poliovirus Replicon RNA

1999 • 197 citations

Non-structural proteins 2 and 3 interact to modify host cell membranes during the formation of the arterivirus replication complex

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Bacterial interactions with the autophagic pathway

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Inhibition of poliovirus RNA synthesis by brefeldin A

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HIV‐1 Egress is Gated Through Late Endosomal Membranes

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Induction of Autophagy Causes Dramatic Changes in the Subcellular Distribution of GFP‐Rab24

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COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI.

1996 • 168 citations

Visualization and Functional Analysis of RNA-Dependent RNA Polymerase Lattices

2002 • 167 citations

Formation of the Poliovirus Replication Complex Requires Coupled Viral Translation, Vesicle Production, and Viral RNA Synthesis

2000 • 166 citations

Inhibition of endoplasmic reticulum-to-Golgi traffic by poliovirus protein 3A: genetic and ultrastructural analysis

1997 • 163 citations

Purification and characterization of autophagosomes from rat hepatocytes

1998 • 162 citations

Inhibition of Autophagy in Mitotic Animal Cells

2002 • 161 citations

Poliovirus 2C protein determinants of membrane binding and rearrangements in mammalian cells

1997 • 161 citations

The Human Endosomal Sorting Complex Required for Transport (ESCRT-I) and Its Role in HIV-1 Budding

2004 • 160 citations

Aspects of the synthesis of poliovirus RNA and the formation of virus particles

1966 • 159 citations

Induction of Membrane Proliferation by Poliovirus Proteins 2C and 2BC

1995 • 130 citations

Involvement of membrane traffic in the replication of poliovirus genomes: Effects of brefeldin A

1992 • 128 citations

A Physico-chemical Sub-grouping of the Mammalian Picornaviruses

1973 • 124 citations

Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy

2000 • 117 citations

Murine Cytomegalovirus CC Chemokine Homolog MCK-2 (m131-129) Is a Determinant of Dissemination That Increases Inflammation at Initial Sites of Infection

2001 • 114 citations

Cargo Can Modulate COPII Vesicle Formation from the Endoplasmic Reticulum

1999 • 110 citations

The Lysosomotropic Agent Monodansylcadaverine Also Acts as a Solvent Polarity Probe

2000 • 105 citations

The Early Secretory Pathway Contributes to Autophagy in Yeast.

2003 • 100 citations

Differential Requirements for COPI Coats in Formation of Replication Complexes among Three Genera of Picornaviridae

2002 • 100 citations

Persistent poliovirus infection of human neuroblastoma cells.

1989 • 96 citations

Evidence that Dot-dependent and -independent factors isolate the Legionella pneumophila phagosome from the endocytic network in mouse macrophages

2001 • 96 citations

Tsg101 Control of Human Immunodeficiency Virus Type 1 Gag Trafficking and Release

2003 • 93 citations

Engineered Retargeting of Viral RNA Replication Complexes to an Alternative Intracellular Membrane

2003 • 84 citations

Analysis of the Intracellular Fate of Legionella pneumophila Mutants^a

1996 • 69 citations

Vectorial release of poliovirus from polarized human intestinal epithelial cells

1993 • 67 citations

Caspase Cleavage of the Nonstructural Protein NS1 Mediates Replication of Aleutian Mink Disease Parvovirus

2003 • 57 citations

Persistent Infection of Human Erythroblastoid Cells by Poliovirus

1993 • 51 citations

Association of poliovirus proteins with the endoplasmic reticulum

1984 • 50 citations

Expression of Mutated Poliovirus Receptors in Human Neuroblastoma Cells Persistently Infected with Poliovirus

2000 • 39 citations

An Alternate Pathway for Recruiting Template RNA to the Brome Mosaic Virus RNA Replication Complex

2003 • 37 citations

Autophagy and Nuclear Changes in FM3A Breast Tumor Cells after Epirubicin, Medroxyprogesterone and Tamoxifen Treatment in vitro

2001 • 35 citations

Poliovirus subviral particles associated with progeny RNA in the replication complex

1995 • 31 citations

Persistent Echovirus Infection of Mouse Cells Expressing the Viral Receptor VLA-2

1997 • 25 citations

Localization of Escherichia coli RNA polymerase binding sites on bacteriophage S13 and 0X174 DNAs by electron microscopy

1979 • 20 citations

Identification of Autolysosomes Directly Associated with Proteolysis on the Density Gradients in Isolated Rat Hepatocytes

1998 • 10 citations

Variability in the integrity of human enteroviruses exposed to various simulatedin vivoenvironments

1998 • 9 citations