Phosphoinositide 3‐phosphatase segregates from phosphatidylinositol 3‐kinase in EGF‐stimulated A431 cells and fails to in vitro hydrolyse phosphatidylinositol(3,4,5)trisphosphate

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Oncogenes and signal transduction

1991 • 2,816 citations

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1993 • 966 citations

Phosphatidylinositol 3-Kinase Encoded by Yeast VPS 34 Gene Essential for Protein Sorting

1993 • 909 citations

Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunit

1992 • 692 citations

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

1987 • 670 citations

Role of Phosphatidylinositol Kinase in PDGF Receptor Signal Transduction

1989 • 516 citations

Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils

1991 • 488 citations

Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands

1985 • 450 citations

A differential location of phosphoinositide kinases, diacylglycerol kinase, and phospholipase C in the nuclear matrix.

1992 • 278 citations

Polyphosphoinositides Produced by Phosphatidylinositol 3-Kinase Are Poor Substrates for Phospholipases C from Rat Liver and Bovine Brain

1989 • 238 citations

Phosphorylation of middle T by pp60c-src: A switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesis

1989 • 178 citations

Phosphoinositide 3-kinase: A new effector in signal transduction?

1991 • 166 citations

Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils?

1990 • 153 citations

Interaction between the epidermal growth factor receptor and phosphoinositide kinases.

1991 • 130 citations

Phosphatidyl-inositol 3-kinase: a key enzyme in diverse signalling processes

1992 • 99 citations

Tyrosine kinases and phosphoinositide metabolism in thrombin-stimulated human platelets

1993 • 63 citations

The novel inositol lipid phosphatidylinositol 3,4-bisphosphate is produced by human blood platelets upon thrombin stimulation

1990 • 61 citations

Isolation and characterization of two 3-phosphatases that hydrolyze both phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.

1991 • 47 citations

Relationship between phosphoinositide kinase activities and protein tyrosine phosphorylation in plasma membranes from A431 cells

1990 • 46 citations

The Discovery of a 3-Phosphomonoesterase That Hydrolyzes Phosphatidylinositol 3-Phosphate in NIH 3T3 Cells

1989 • 45 citations

Anti-phosphotyrosine immunoprecipitation of phosphatidylinositol 3′ kinase activity in different cell types after exposure to epidermal growth factor

1990 • 20 citations