Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils?

Inositol phosphates and cell signalling

1989 • 4,058 citations

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

1989 • 933 citations

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

1985 • 824 citations

Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate

1987 • 624 citations

The Actin-Binding Protein Profilin Binds to PIP ₂ and Inhibits Its Hydrolysis by Phospholipase C

1990 • 472 citations

From signal to pseudopod

1989 • 460 citations

Chemoattractant receptor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in human polymorphonuclear leukocyte membranes. Requirement for a guanine nucleotide regulatory protein.

1985 • 358 citations

An inositol tetrakisphosphate-containing phospholipid in activated neutrophils

1988 • 292 citations

Signal transduction and cytoskeletal activation in the neutrophil.

1987 • 282 citations

Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils

1989 • 256 citations

Human platelets form 3-phosphorylated phosphoinositides in response to alpha-thrombin, U46619, or GTP gamma S.

1990 • 204 citations

Gelsolin-Polyphosphoinositide Interaction

1989 • 200 citations

The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil.

1984 • 178 citations

Relationship of actin polymerization and depolymerization to light scattering in human neutrophils: dependence on receptor occupancy and intracellular Ca++.

1985 • 178 citations

Specificity of the interaction between phosphatidylinositol 4,5‐bisphosphate and the profilin:actin complex

1988 • 168 citations

Reversible binding of actin to gelsolin and profilin in human platelet extracts.

1987 • 162 citations

Association of gelsolin with actin filaments and cell membranes of macrophages and platelets.

1989 • 151 citations

Evidence that the phosphatidylinositol cycle is linked to cell motility

1988 • 131 citations

Pieces in the actin-severing protein puzzle

1988 • 112 citations

Characterization of platelet extracts before and after stimulation with respect to the possible role of profilactin as microfilament precursor

1981 • 100 citations

The effect of divalent cations on the interaction between calf spleen profilin and different actins

1988 • 84 citations

Increased breakdown of phosphatidylinositol 4,5-bisphosphate is not an initiating factor for actin assembly in human neutrophils.

1988 • 58 citations

A High-Yield, High-Purity Elutriation Method for Preparing Human Granulocytes Demonstrating Enhanced Experimental Lifetimes

1987 • 43 citations

Methionine modification in cytochrome-c peroxidase

1988 • 19 citations

Kinetics and amplification in neutrophil activation and adaptation.

1990 • 14 citations