Comparison of p53 and DNA content abnormalities in adenocarcinoma of the oesophagus and gastric cardia

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

1994 • 3,536 citations

Rising Incidence of Adenocarcinoma of the Esophagus and nGastric Cardia

1991 • 2,278 citations

Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry.

1983 • 2,066 citations

The 1993–94 Généthon human genetic linkage map

1994 • 1,870 citations

The p53-mdm-2 autoregulatory feedback loop.

1993 • 1,795 citations

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

1991 • 1,525 citations

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1992 • 1,358 citations

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

1992 • 1,117 citations

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.

1990 • 1,080 citations

Barrett's esophagus

1987 • 710 citations

Structural aspects of the p53 protein in relation to gene evolution.

1990 • 618 citations

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1992 • 567 citations

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein.

1991 • 544 citations

Rising incidence of adenocarcinoma of the esophagus and gastric cardia

1991 • 531 citations

Adenocarcinoma and Barrett's esophagus. An overrated risk?

1984 • 442 citations

Increasing incidence of adenocarcinoma of the gastric cardia and adjacent sites

1990 • 400 citations

The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13).

1986 • 371 citations

p53 expression and prognosis in gastric carcinoma

1992 • 333 citations

Barrett's esophagus

1987 • 282 citations

p53 alteration in gastric precancerous lesions.

1994 • 229 citations

Barrett's metaplasia and adenocarcinoma of the esophagus and gastroesophageal junction

1983 • 225 citations

Clinical, Epidemiologic and Morphologic Comparison Between Adenocarcinomas Arising in Barrett's Esophageal Mucosa and in the Gastric Cardia

1984 • 221 citations

Loss of heterozygosity involves multiple tumor suppressor genes in human esophageal cancers.

1992 • 215 citations

Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas

1992 • 197 citations

p53 Mutation in gastric cancer: A genetic model for carcinogenesis is common to gastric and colorectal cancer

1993 • 195 citations

Comparative features of esophageal and gastric adenocarcinomas: Recent changes in type and frequency

1986 • 177 citations

TP53 gene mutations and p53 protein immunoreactivity in malignant and premalignant Barrett's esophagus

1994 • 172 citations

p53 Mutations in Barrett's adenocarcinoma and high-grade dysplasia

1994 • 146 citations

Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma.

1993 • 146 citations

17p allelic losses in diploid cells of patients with Barrett's esophagus who develop aneuploidy.

1994 • 142 citations

17p allelic deletions and p53 protein overexpression in Barrett's adenocarcinoma.

1991 • 138 citations

Mutations of the K-ras and p53 genes in gastric adenocarcinomas from a high-incidence region around Florence, Italy.

1995 • 128 citations

The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma

1992 • 120 citations

Prognostic value of DNA ploidy and cerbB-2 oncoprotein overexpression in adenocarcinoma of Barrett's esophagus

1994 • 120 citations

Base transitions are the most frequent genetic changes at P53 in gastric cancer.

1993 • 105 citations

Stabilised p53 facilitates aneuploid clonal divergence in colorectal cancer.

1993 • 102 citations

Barrett's esophagus. Correlation between mucin histochemistry, flow cytometry, and histologic diagnosis for predicting increased cancer risk.

1988 • 97 citations

Accumulation of p53 protein in normal, dysplastic, and neoplastic Barrett's oesophagus

1995 • 84 citations

A study of stabilisation of p53 protein versus point mutation in colorectal carcinoma.

1994 • 77 citations

Base transitions at CpG dinucleotides in the p53 gene are common in esophageal adenocarcinoma.

1995 • 77 citations

Overexpression of p53 protein in Barrett's syndrome with malignant transformation.

1993 • 76 citations

Adenocarcinoma arising in Barrett's oesophagus: evidence for the participation of p53 dysfunction in the dysplasia/carcinoma sequence.

1994 • 61 citations

P53 mutations in gastric carcinomas

1992 • 53 citations

Loss of heterozygosity and K-ras gene mutations in gastric cancer

1993 • 53 citations

Over expression of the p53 tumor suppressor gene product in esophageal and gastric carcinomas

1994 • 32 citations

Mutational Spectrometry in Animal Toxicity Testing

1990 • 29 citations

DNA ploidy in early gastric carcinoma (T1): a flow cytometric study of 100 European cases.

1993 • 26 citations

The Value of Flow Cytometric Analysis in Patients With Gastric Cancer

1993 • 26 citations

Dinucleotide repeat polymorphism at the D17S514 locus

1991 • 20 citations

Changing Patterns in Gastric Carcinoma

1989 • 13 citations

Independent clinical and flow cytometric prognostic factors for the survival of patients with stage I gastric cancer

1992 • 10 citations

Mutational Spectrometry In Animal Toxicity Testing

1990 • 2 citations