Contrasting effects of alpha, beta, and gamma interferons on nonspecific suppressor function in multiple sclerosis

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Treatment of multiple sclerosis with gamma interferon

1987 • 739 citations

Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).

1988 • 680 citations

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

1985 • 440 citations

Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: Do cytokines trigger off exacerbations?

1988 • 404 citations

Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

1988 • 392 citations

In Vivo Activated T Lymphocytes in the Peripheral Blood and Cerebrospinal Fluid of Patients with Multiple Sclerosis

1985 • 307 citations

Regulation of T‐Cell Activation; Differences among T‐Cell Subsets

1989 • 271 citations

Antagonistic effect of interferon-beta on the interferon-gamma-induced expression of Ia antigen in murine macrophages.

1985 • 207 citations

Three distinct classes of regulatory cytokines control endothelial cell MHC antigen expression. Interactions with immune gamma interferon differentiate the effects of tumor necrosis factor and lymphotoxin from those of leukocyte alpha and fibroblast beta interferons.

1988 • 142 citations

Contrasting effect of alpha/beta- and gamma-interferons on expression of macrophage Ia antigens.

1986 • 138 citations

Systemic alpha‐interferon therapy of multiple sclerosis

1984 • 128 citations

Interfer beta augments supperssor cell function in multiple sclerosis

1990 • 120 citations

Detection of in Vivo Stimulated Cerebrospinal-Fluid Lymphocytes by Flow Cytometry in Patients with Multiple Sclerosis

1980 • 111 citations

Interferon-β impairs induction of HLA-DR antigen expression in cultured adult human astrocytes

1989 • 98 citations

The distribution of interleukin-2 receptor bearing lymphocytes in multiple sclerosis: evidence for a key role of activated lymphocytes.

1985 • 97 citations

Interferon responses of leukocytes in multiple sclerosis

1981 • 95 citations

Lymphocytes from multiple sclerosis patients produce elevated levels of gamma interferonin vitro

1985 • 94 citations

Intrathecally Administered Natural Human Fibroblast Interferon Reduces Exacerbations of Multiple Sclerosis

1987 • 79 citations

Systemic lymphoblastoid interferon therapy in chronic progressive multiple Sclerosis. I. Clinical and MRI evaluation

1990 • 77 citations

Cytotoxic activity and interferon production by lymphocytes from patients with multiple sclerosis.

1981 • 74 citations

Systemic Recombinant -2Interferon Therapy in Relapsing Multiple Sclerosis

1986 • 73 citations

Suppressor cell function in multiple sclerosis.

1978 • 67 citations

Characterization of three monoclonal antibodies that recognize the interferon alpha 2 receptor.

1990 • 55 citations

Activation of a suppressor T-cell pathway by interferon.

1982 • 54 citations

Suppressor T cell activation by human leukocyte interferon.

1983 • 53 citations

Activated T lymphocytes in patients with multiple sclerosis

1983 • 51 citations

Multiple sclerosis: Activated cells in cerebrospinal fluid in acute exacerbations

1985 • 28 citations

Activated suppressor cell function in multiple sclerosis — clinical correlations☆

1988 • 23 citations

Interferon production by lymphocytes from multiple sclerosis and non‐MS patients

1983 • 21 citations

Interferon production by cultured peripheral leucocytes of MS patients.

1984 • 19 citations

Interferon induction, 2′-5′ oligo A synthetase and lymphocyte subpopulations in out-patients with multiple sclerosis in a longitudinal study

1986 • 8 citations