Lymphocytes from multiple sclerosis patients produce elevated levels of gamma interferonin vitro

Isolation of Lymphocytes, Granulocytes and Macrophages

1976 • 1,621 citations

Response of resting human peripheral blood natural killer cells to interleukin 2.

1984 • 616 citations

Recombinant interferon-gamma increases HLA-DR synthesis and expression.

1983 • 577 citations

Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets.

1983 • 483 citations

Activation of human macrophages. Comparison of other cytokines with interferon-gamma.

1984 • 362 citations

Suppressor cell function in multiple sclerosis: Correlation with clinical disease activity

1979 • 251 citations

Lymphokine enhances the expression and synthesis of Ia antigens on cultured mouse peritoneal macrophages.

1980 • 238 citations

γ-Interferon is one of several direct B cell-maturing lymphokines

1984 • 237 citations

Functional identity between murine γ Interferon and macrophage activating factor

1983 • 206 citations

Role of γ-interferon in antibody-producing responses

1984 • 203 citations

Interferon-γ induces the expression of H-2 and Ia antigens on brain cells

1984 • 182 citations

Regulation of murine macrophage Ia-antigen expression by products of activated spleen cells.

1980 • 162 citations

Cellular immune responses during complicated and uncomplicated measles virus infections of man

1984 • 145 citations

Use of monoclonal antibodies as sensitive and specific probes for biologically active human gamma-interferon.

1984 • 130 citations

Multiple sclerosis: Diagnostic usefulness of cerebrospinal fluid

1977 • 114 citations

γ Interferon induced by S. aureus protein A augments natural killing and ADCC

1981 • 112 citations

Interferon responses of leukocytes in multiple sclerosis

1981 • 95 citations

Human gamma interferon production by leukocytes induced with monoclonal antibodies recognizing T cells.

1981 • 85 citations

Decreased NK killing in patients with multiple sclerosis: an analysis on the level of the single effector cell in peripheral blood and cerebrospinal fluid in relation to the activity in the disease.

1982 • 83 citations

Endogenous and interferon-augmented natural killer cell activity of human peripheral blood mononuclear cells in vitro. Studies of patients with multiple sclerosis, systemic lupus erythematosus or rheumatoid arthritis.

1982 • 83 citations

Response to and production of interleukin 2 by peripheral blood and cerebrospinal fluid lymphocytes of patients with multiple sclerosis.

1984 • 71 citations

Oligoclonal immunoglobulin G in multiple sclerosis brains

1972 • 66 citations

Correction of defective macrophage differentiation in C3H/HeJ mice by an interferon-like molecule.

1982 • 65 citations

Abnormal regulation of IgG production in multiple sclerosis

1982 • 49 citations

Interferon production and natural killer (NK) activity in leukocyte cultures from multiple sclerosis patients

1983 • 43 citations

Defective immunoreguktion in multiple sclerosis

1980 • 38 citations

Mitogen-induced plasma cell differentiation in patients with multiple sclerosis.

1980 • 30 citations

The effect of recombinant alpha ₂ ‐interferon on defective natural killer cell activity in multiple sclerosis

1985 • 29 citations

Defective immunoregulation in multiple sclerosis.

1979 • 23 citations