Functional analysis of influenza-specific helper T cell clones in vivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin.

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

DISQUISITIONS ON ORIGINAL ANTIGENIC SIN

1966 • 568 citations

Complete replacement of serum by albumin, transferrin, and soybean lipid in cultures of lipopolysaccharide-reactive B lymphocytes.

1978 • 535 citations

Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus

1978 • 528 citations

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination

1985 • 522 citations

Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors.

1984 • 422 citations

Factors Affecting B-Cell Growth and Differentiation

1985 • 354 citations

Studies on the capacity of B cells to serve as antigen-presenting cells.

1981 • 349 citations

Crystalline Antigen from the Influenza Virus Envelope

1972 • 346 citations

Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas.

1982 • 252 citations

Use of Monoclonal Anti-mouse Immunoglobulin to Detect Mouse Antibodies

1981 • 252 citations

Interleukin 2 receptors on human B cells. Implications for the role of interleukin 2 in human B cell function.

1985 • 249 citations

Antigenic variation in three distinct determinants of an influenza type A haemagglutinin molecule

1979 • 203 citations

Role of γ-interferon in antibody-producing responses

1984 • 203 citations

Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells.

1982 • 202 citations

Antigen presentation by normal B cells, B cell tumors, and macrophages: functional and biochemical comparison.

1982 • 199 citations

Host Defenses Against Influenza Virus: The Role of Anti-Hemagglutinin Antibody

1975 • 183 citations

Antigen presentation by resting B cells. Radiosensitivity of the antigen-presentation function and two distinct pathways of T cell activation.

1984 • 182 citations

B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor.

1981 • 159 citations

Major histocompatibility complex-restricted, polyclonal B cell responses resulting from helper T cell recognition of antiimmunoglobulin presented by small B lymphocytes.

1985 • 154 citations

Major histocompatibility complex-restricted antigen presentation to antigen-reactive T cells by B lymphocyte tumor cells.

1981 • 153 citations

Thymus dependence of viral antigens

1975 • 145 citations

CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE

1971 • 140 citations

T cells primed by influenza virion internal components can cooperate in the antibody response to haemagglutinin

1979 • 125 citations

ANTIBODY RESPONSES TO ANTIGENIC DETERMINANTS OF INFLUENZA VIRUS HEMAGGLUTININ

1974 • 122 citations

Culture supernatants of a stimulated T-cell line have helper activity that acts synergistically with interleukin 2 in the response of B cells to antigen.

1981 • 119 citations

Regulatory Mechanisms in the Immune Response to Cell-surface Antigens

1977 • 118 citations

Cytotoxic T Cells in the Lungs of Mice Infected with an Influenza A Virus

1978 • 115 citations

H‐2‐unrestricted polyclonal maturation without replication of small B cells induced by antigen‐activated T cell help factors

1980 • 112 citations

Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis.

1984 • 106 citations

Antigen presentation by human B cells: T cell proliferation induced by Epstein Barr virus B lymphoblastoid cells.

1982 • 103 citations

"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta.

1985 • 98 citations

Influenza Virus Infection in Nude Mice

1976 • 87 citations

Lack of mature B cells in nude mice with X-linked immune deficiency.

1982 • 83 citations

Role of the major histocompatibility complex in T cell activation of B cell subpopulations. lyb-5(+) and lyb-5(-) B cell subpopulations differ in their requirement for major histocompatibility complex-restricted T cell recognition

1981 • 82 citations

The Recovery of Mice from Influenza Virus Infection: Adoptive Transfer of Immunity with Immune T Lymphocytes

1978 • 81 citations

In vitro influenza virus-specific antibody production in man: antigen-specific and HLA-restricted induction of helper activity mediated by cloned human T lymphocytes.

1982 • 75 citations

Influenza A specific cytotoxic T-cell clones that do not recognize viral glycoproteins

1982 • 74 citations

Selective reconstitution of nude mice with long-term cultured and cloned specific helper T cells

1980 • 73 citations

IMMUNE RESPONSES TO INFLUENZA VIRUS IN THE MOUSE, AND THEIR ROLE IN CONTROL OF THE INFECTION

1979 • 69 citations

Role of T-cell function in recovery from murine influenza infection

1979 • 63 citations

Cytotoxic T-memory cells in virus infection and the specificity of helper T cells.

1982 • 58 citations

Evidence that cytotoxic T cells are part of the host's response to influenza pneumonia.

1978 • 55 citations

Role of antigen-specific B cells in the induction of SRBC-specific T cell proliferation.

1984 • 48 citations

Murine TH response to influenza virus: recognition of hemagglutinin, neuraminidase, matrix, and nucleoproteins.

1985 • 46 citations

Monoclonal Antibodies against Influenza Virus

1980 • 38 citations

The recognition specificity of a murine helper T cell for hemagglutinin of influenza virus A/PR/8/34.

1983 • 36 citations

Cell cooperation in antibody responses to influenza virus. I. Priming of helper T cells by internal components of the virion

1980 • 33 citations

Influenza viruses are T cell-independent B cell mitogens

1984 • 33 citations

Factors Affecting B-Cell Growth and Differentiation

1985 • 25 citations

Cellular interactions involved in T-dependent B-cell activation

1982 • 22 citations

Influenza Virus-Specific Murine T Cell Hybridomas Which Recognize Virus Hemagglutinin in Conjunction with H-2d and Display Helper Functions for B Cells

1982 • 14 citations

Structure of Influenza Virus

1974 • 5 citations